Hasanchez_picture_2018.jpg_thumb90

HELMUTH ALBERTO SANCHEZ RIQUELME

INVESTIGADOR JOVEN

CENTRO INTERDISCIPLINARIO DE NEUROCIENCIAS DE VALPARAISO

VALPARAISO, Chile

Líneas de Investigación


FISIOLOGIA; NEUROCIENCIAS; BIOFISICA

Educación

  •  DOCTORADO en CIENCIAS BIOLOGICAS, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2008
  •  LICENCIATURA en CS.BIOLOGICAS, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2000

Experiencia Académica

  •   INVESTIGADOR ASOCIADO Full Time

    ALBERT EINSTEIN COLLEGE OF MEDICINE

    Estados Unidos

    Enero 2015 - Enero 2016

Experiencia Profesional

  •   POSTDOCTORADO Full Time

    ALBERT EINSTEIN COLLEGE OF MEDICINE

    Estados Unidos

    Enero 2008 - Enero 2015


Tipos de Producción
 

Article (9)

Syndromic deafness mutations at Asn 14 differentially alter the open stability of Cx26 hemichannels
Aberrant Cx26 hemichannels and keratitis-ichthyosis-deafness syndrome: insights into syndromic hearing loss
Altered Inhibition of Cx26 Hemichannels by pH and Zn2+ in the A40V Mutation Associated with Keratitis-Ichthyosis-Deafness Syndrome
The D50N mutation and syndromic deafness: Altered Cx26 hemichannel properties caused by effects on the pore and intersubunit interactions
Mechanism of inhibition of connexin channels by the quinine derivative N-benzylquininium
Regulation of Intercellular Calcium Signaling Through Calcium Interactions with Connexin-Based Channels
Connexin 43 hemichannels mediate the Ca2+ influx induced by extracellular alkalinization
Differentially altered Ca(2+) regulation and Ca(2+) permeability in Cx26 hemichannels formed by the A40V and G45E mutations that cause keratitis ichthyosis deafness syndrome
Metabolic inhibition increases activity of connexin-32 hemichannels permeable to Ca2+ in transfected HeLa cells

Abstract (2)

Cx43 hemichannels in HeLa cells expressing Cx43 or Cx43-EGFP and in cultured astrocytes under control conditions and during metabolic inhibition
Metabolic inhibition induces dephosphorylation and opening of gap junction hemichannels formed by connexin43

Review (1)

Redox-mediated regulation of connexin proteins; focus on nitric oxide

Grant (1)

IDENTIFICACION DE MUTACIONES CAUSANTES DE SORDERA CONGENITA

Nil Class (0)

13
HELMUTH SANCHEZ

INVESTIGADOR JOVEN

Laboratorio de Conexinas y Panexinas

CENTRO INTERDISCIPLINARIO DE NEUROCIENCIAS DE VALPARAISO

VALPARAISO, Chile

2
Juan Orellana

Assistant Professor

Departamento de Neurología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Juan Saez

Professor

Physiology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Isaac Garcia

Profesor Adjunto

Instituto de Neurociencias

Universidad de Valparaiso

Valparaiso, Chile

1
Juan Sáez

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Vania Figueroa

Profesor Asistente

Instituto de Ciencias de la Salud

Universidad de O’Higgins

Rancagua, Chile

1
Agustin Martinez

Profesor Titular

Instituto de Neurociencia

UNIVERSIDAD DE VALPARAÍSO, CENTRO INTERDISCIPLINARIO DE NEUROCIENCIAS DE VALPARAÍSO

Valparaíso, Chile