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Carlos Alfonso Valenzuela Bonomo

INTA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

METABOLISMO DE ACIDOS GRASOS; ANTIOXIDANTES Y ESTRES OXIDATIVO; TECNOLOGIA DE MATERIAS GRASAS; Metabolismo de cidos grasos poliinsaturados; Efectos citoprotectores de Ã¡cidos grasos poliinsaturados omega-3 de origen; Propiedades funcionales de aceites vegetales; metabolismo de acidos grasos; antioxidantes y estres oxidativo; tecnologias en materias grasas

Boquímico, UNIVERSIDAD DE CHILE. Chile, 1970

Profesor Titular Full Time

UNIVERSIDAD DE CHILE

INTA

Santiago, Chile

1972 - A la fecha


Iron-induced pro-oxidant and pro-lipogenic responses in relation to impaired synthesis and accretion of long-chain polyunsaturated fatty acids in rat hepatic and extrahepatic tissues Valenzuela, Rodrigo; Rincón-Cervera, Miguel Ángel; Echeverría, Francisca; Barrera, Cynthia; Espinosa, Alejandra; Hernández-Rodas, María Catalina; Ortiz, Macarena; Valenzuela, Alfonso; Videla, Luis A. Article ISI SCOPUS NUTRITION (2018)
Comparison of fatty acid profiles of dried and raw by-products from cultured and wild fishes Rincón-Cervera, Miguel Ángel; Villarreal-Rubio, María Beatriz; Valenzuela, Rodrigo; Valenzuela, Alfonso Article ISI SCOPUS EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY (2017)
Hydroxytyrosol prevents reduction in liver activity of Delta-5 and Delta-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice Valenzuela, Rodrigo; Echeverria, Francisca; Ortiz, Macarena; Rincón-Cervera, Miguel Ángel; Espinosa, Alejandra; Hernandez-Rodas, María Catalina; Illesca, Paola; Valenzuela, Alfonso; Videla, Luis A. Article ISI SCOPUS LIPIDS IN HEALTH AND DISEASE (2017)
Liver Protective Effects of Extra Virgin Olive Oil: Interaction between Its Chemical Composition and the Cell-signaling Pathways Involved in Protection Soto-Alarcon, Sandra A.; Valenzuela, Rodrigo; Valenzuela, Alfonso; Videla, Luis A. Article Endocrine, Metabolic & Immune Disorders - Drug Targets (2017)
Molecular adaptations underlying the beneficial effects of hydroxytyrosol in the pathogenic alterations induced by a high-fat diet in mouse liver: PPAR-alpha and Nrf2 activation, and NF-kappa B down-regulation Valenzuela, Rodrigo; Illesca, Paola; Echeverría, Francisca; Espinosa, Alejandra; Rincón-Cervera, Miguel Ángel; Ortiz, Macarena; Hernandez-Rodas, María Catalina; Valenzuela, Alfonso; Videla, Luis A. Article ISI SCOPUS FOOD FUNCTION (2017)
Effect of water availability on growth efficiency in water use and content of omega-3 in two genotypes of chia established in the Mediterranean arid zone of Chile Silva H, Garrido M, Baginsky C, Valenzuela A,Valenzuela C, et al Article ISI AGRICULTURAL WATER MANAGEMENT (2016)
Extra virgin olive oil reduces liver oxidative stress and tissue depletion of long-chain polyunsaturated fatty acids produced by a high saturated fat diet in mice Valenzuela R.; Hernandez-Rodas, M.C.; Espinosa, A.; Rincón M.A.; Romero, N; Barrera C.; Marambio, M; Vivero J.; Valenzuela A. Article ISI SCOPUS Grasas y Aceites (2016)
Vegetable oils rich in alpha linolenic acid increment hepatic n-3 LCPUFA, modulating the fatty acid metabolism and antioxidant response in rats Rincón-Cervera, Miguel Ángel; Valenzuela, Rodrigo; Hernandez-Rodas, María Catalina; Barrera, Cynthia; Espinosa, Alejandra; Marambio, Macarena; Valenzuela, Alfonso Article ISI SCOPUS PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2016)
Modification of Docosahexaenoic Acid Composition of Milk from Nursing Women Who Received Alpha Linolenic Acid from Chia Oil during Gestation and Nursing Valenzuela R.; Bascunan, KA; Chamorro R.; Barrera C.; Sandoval, J; Puigrredon C.; Parraguez, G.; Orellana P.; González V.; Valenzuela A. Article ISI SCOPUS NUTRIENTS (2015)
Alpha linolenic acid (ALA) from Rosa canina, sacha inchi and chia oils may increase ALA accretion and its conversion into n-3 LCPUFA in diverse tissues of the rat Valenzuela R.; Barrera C.; Gonzalez-Astorga, M; Sanhueza, J; Valenzuela A. Article ISI SCOPUS FOOD FUNCTION (2014)
Polyunsaturated Fatty Acid Composition of Maternal Diet and Erythrocyte Phospholipid Status in Chilean Pregnant Women Bascunan, KA; Valenzuela R.; Chamorro R.; Valencia, A; Barrera C.; Puigrredon C.; Sandoval, J; Valenzuela A. Article ISI SCOPUS Nutrients (2014)
Vegetable oils rich in alpha linolenic acid allow a higher accretion of n-3 LCPUFA in the plasma, liver and adipose tissue of the rat Valenzuela R.; Barrera C.; Ayala, JM.; Sanhueza, J; Valenzuela A. Article ISI SCOPUS GRASAS Y ACEITES (2014)
Bioconversion of alpha-linolenic acid to n-3 LCPUFA and expression of PPAR-alpha, acyl coenzyme A oxidase 1 and carnitine acyl transferase I are incremented after feeding rats with alpha-linolenic acid-rich oils Gonzalez-Manan, D; Tapia, G; Gormaz J.G.; D'Espessailles A.; Espinosa, A.; Masson L.; Varela, P; Valenzuela A.; Valenzuela R. Article ISI SCOPUS Food and Function (2012)
Cholesterol metabolism: increasingly complex Sanhueza, J; Valenzuela R.; Valenzuela A. Article ISI SCOPUS Grasas y Aceites (2012)
The oleic acid esterification of policosanol increases its bioavailability and hypocholesterolemic action in rats Haim, D; Valenzuela A.; Branes M.C.; Fuenzalida, M; Videla, L.A. Article ISI SCOPUS Grasas y Aceites (2012)
Supplementing female rats with DHA-lysophosphatidylcholine increases docosahexaenoic acid and acetylcholine contents in the brain and improves the memory and learning capabilities of the pups Valenzuela A.; Nieto S.; Sanhueza, J; Morgado, N; Rojas I.; Zanartu, P Article ISI SCOPUS Grasas y Aceites (2010)
Trace quantification of 1-octacosanol and 1-triacontanol and their main metabolites in plasma by liquid-liquid extraction coupled with gas chromatography-mass spectrometry Haim, D; Berríos M; Valenzuela A.; Videla LA. Article ISI SCOPUS JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2009)
Comparative effect of fish oil feeding and other dietary fatty acids on plasma lipoproteins, biliary lipids, and hepatic expression of proteins involved in reverse cholesterol transport in the rat Morgado, N; Rigotti, A.; Valenzuela A. Article ISI SCOPUS ANNALS OF NUTRITION AND METABOLISM (2005)
Effect of supplementation with docosahexaenoic acid ethyl ester and sn-2 docosahexaenyl monoacylglyceride on plasma and erythrocyte fatty acids in rats Valenzuela A.; Valenzuela, V.; Sanhueza, J; Nieto S. Article ISI SCOPUS ANNALS OF NUTRITION AND METABOLISM (2005)
Tissue accretion and milk content of docosahexaenoic acid in female rats after supplementation with different docosahexaenoic acid sources Valenzuela A.; Nieto S.; Sanhueza, J; Nunez, MJ; Ferrer, C. Article ISI SCOPUS ANNALS OF NUTRITION AND METABOLISM (2005)
ACIDO DOCOSAHEXAENOICO (DHA), DESARROLLO CEREBRAL, MEMORIA Y APRENDIZAJE: LA IMPORTANCIA DE LA SUPLEMENTACIÓN PERINATAL Sanhueza, Julio; Nieto, Susana; Valenzuela, Alfonso Article SCIELO REVISTA CHILENA DE NUTRICION (2004)
Inhibitory action of conventional food-grade natural antioxidants and of natural antioxidants of new development on the thermal-induced oxidation of cholesterol Valenzuela A.; Sanhueza, J; Alonso P.; Corbari A.; Nieto S. Article ISI SCOPUS INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION (2004)
Supplementation of female rats with alpha-linolenic acid or docosahexaenoic acid leads to the same omega-6/omega-3 LC-PUFA accretion in mother tissues and in fetal and newborn brains Valenzuela A.; von Bernhardi R.; Valenzuela, V.; Ramirez G.; Alarcon, R; Sanhueza, J; Nieto S. Article ISI SCOPUS ANNALS OF NUTRITION AND METABOLISM (2004)
Effect of the degree of hydrogenation of fish oil on the enzymatic activity and on the fatty acid composition of hepatic microsomes from young and aged rats Morgado, N; Sanhueza, J; Nieto S.; Valenzuela A. Article ISI SCOPUS ANNALS OF NUTRITION AND METABOLISM (2003)
Differential inhibitory effect of alpha-, beta-, gamma-, and delta-tocopherols on the metal-induced oxidation of cholesterol in unilamellar phospholipid-cholesterol liposomes Valenzuela A.; Sanhueza, J; Nieto S. Article ISI SCOPUS JOURNAL OF FOOD SCIENCE (2002)
Effect of synthetic antioxidants on cholesterol stability during the thermal-induced oxidation of a polyunsaturated vegetable oil Valenzuela A.; Sanhueza, J; Nieto S. Article ISI SCOPUS JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY (2002)
Marine oils: The health benefits of n-3 fatty acids Uauy R.; Valenzuela A. Article ISI NUTRITION (2000)
Thermal stability of some commercial synthetic antioxidants Sanhueza, J; Nieto S.; Valenzuela A. Article ISI SCOPUS JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY (2000)


LCP metabolism and endogenous bioequivalence of intermediates in the formation of DHA and AA using deuterated precursors Llanos, AR; Mena, P; Valenzuela A.; Salem, N.; Uauy R. Abstract ISI PEDIATRIC RESEARCH (2003)


Chia: an atractive source of essential n-3 alpha linolenic acid for human nutrition. Metabolic aspects. Valenzuela R, Valenzuela A BookSection (2017)
Resent trends in research on bioactive lipids: How to enhance dietary DHA bioavailability in humans Rincon MA, Valenzuela R, Valenzuela A. BookSection (2017)


Docosahexaenoic acid (DHA), a fundamental fatty acid for the brain: New dietary sources Echeverría F.; Valenzuela R.; Catalina Hernandez-Rodas M.; Valenzuela A. Review ISI SCOPUS PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2017)
Stearic acid: a possible substitute for trans fatty acids from industrial origin Valenzuela A.; Delplanque B.; Tavella, M Review ISI SCOPUS Grasas y Aceites (2011)
Docosahexaenoic acid (DHA), an essential fatty acid for the proper functioning of neuronal cells: their role in mood disorders Valenzuela A. Review ISI SCOPUS GRASAS Y ACEITES (2009)
Docosahexaenoic acid (DHA), essentiality and requirements: why and how to provide supplementatlion Valenzuela A.; Sanhueza, BJ; Nieto S. Review ISI GRASAS Y ACEITES (2006)
Cholesterol oxidized products in foods: Potential health hazards and the role of antioxidants in prevention Valenzuela A.; Sanhueza, J; Nieto S. Review ISI SCOPUS GRASAS Y ACEITES (2004)
Cholesterol oxidation: Health hazard and the role of antioxidants in prevention Valenzuela A.; Sanhueza, J; Nieto S. Review ISI SCIELO BIOLOGICAL RESEARCH (2003)
Natural antioxidants in functional foods: from food safety to health benefits Valenzuela A.; Sanhueza, J; Nieto S. Review ISI GRASAS Y ACEITES (2003)
Docosahexanoic acid (DNA) in fetal development and infant nutrition Valenzuela A.; Nieto, MS Review ISI REVISTA MEDICA DE CHILE (2001)