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Francisco Javier Olivares Silva

Pharmacology PhD(c)

Universidad de Chile

Santiago, Chile

Líneas de Investigación


Cardiac fibroblasts and inflammation; Specialized pro-resolving mediators and cardiac function

Educación

  •  Pharmaceutical Chemist, UNIVERSIDAD DE CHILE. Chile, 2016
  •  BSc Pharmaceutical Sciences, UNIVERSIDAD DE CHILE. Chile, 2015
  •  Phd in Pharmacology, UNIVERSIDAD DE CHILE. Chile, 2021

Experiencia Académica

  •   Undergraduate Teaching Assistant (Toxicology) Part Time

    UNIVERSIDAD DE CHILE

    Faculty of Chemical Sciences and Pharmacy

    Santiago, Chile

    2016 - 2016

  •   Undergraduate Teaching Assistant (Medicinal Chemistry I) Part Time

    UNIVERSIDAD DE CHILE

    Faculty of Chemical Sciences and Pharmacy

    Santiago, Chile

    2019 - 2020

Premios y Distinciones

  •   Beca SOFARCHI

    SOCIEDAD DE FARMACOLOGIA DE CHILE

    Chile, 2016

    The Chilean Society of Pharmacology, through its board of directors, opened a call for the SOFARCHI 2016 Scholarship for undergraduate and master students who were sponsored by active members of our society. The objective was to provide financial aid so that students could finance part of their expenses during the development of the XXXVIII congress.


 

Article (6)

TGF-β1 decreases CHOP expression and prevents cardiac fibroblast apoptosis induced by endoplasmic reticulum stress

Olivares-Silva, F.; Espitia-Corredor, J.; Letelier, A.; Vivar, R.; Parra-Flores, P.; Olmedo, I.; Montenegro, J.; Pardo-Jiménez, V.; Díaz-Araya, G.

Article
Toxicology In Vitro  (2021)

In cardiac fibroblasts, interferon-beta attenuates differentiation, collagen synthesis, and TGF-β1-induced collagen gel contraction

Bolivar, S.; Espitia-Corredor, J.A.; Olivares-Silva, F.; Valenzuela, P.; Humeres, C.; Anfossi, R.; Castro, E.; Vivar, R.; Salas-Hernández, A.; Pardo-Jiménez, V.; Díaz-Araya, G.

Article
Cytokine  (2020)

Expression and function of TLR4-induced B1R bradykinin receptor on cardiac fibroblasts

Munoz-Rodriguez, Claudia; Fernandez, Samuel; Miguel Osorio, Jose; Olivares, Francisco; Anfossi, Renatto; Bolivar, Samir; Humeres, Claudio; Boza, Pia; Vivar, Raul; Pardo-Jimenez, Viviana; Hemmings, Karen E.; Turner, Neil A.; Diaz-Araya, Guillermo

Article ISI SCOPUS
TOXICOLOGY AND APPLIED PHARMACOLOGY  (2018)

Heparan sulfate potentiates leukocyte adhesion on cardiac fibroblast by enhancing Vcam-1 and Icam-1 expression

Olivares-Silva, Francisco; Landaeta, Rodolfo; Aranguiz, Pablo; Bolivar, Samir; Humeres, Claudio; Anfossi, Renatto; Vivar, Raul; Boza, Pia; Munoz, Claudia; Pardo-Jimenez, Viviana; Peiro, Concepcion; Sanchez-Ferrer, Carlos F.; Diaz-Araya, Guillermo

Article ISI SCOPUS
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE  (2018)

IFN-beta Plays Both Pro- and Anti-inflammatory Roles in the Rat Cardiac Fibroblast Through Differential STAT Protein Activation

Bolivar, Samir; Anfossi, Renatto; Humeres, Claudio; Vivar, Raul; Boza, Pia; Munoz, Claudia; Pardo-Jimenez, Viviana; Olivares-Silva, Francisco; Diaz-Araya, Guillermo

Article ISI SCOPUS
FRONTIERS IN PHARMACOLOGY  (2018)

Cardiac fibroblast cytokine profiles induced by proinflammatory or profibrotic stimuli promote monocyte recruitment and modulate macrophage M1/M2 balance in vitro

Humeres, C; Vivar, R; Boza, P; Munoz, C; Bolivar, S; Anfossi, R; Osorio, JM; Olivares-Silva, F; Garcia, L; Diaz-Araya, G

Article ISI SCOPUS
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY  (2016)

ConferencePoster (3)

Resolvin D1 prevents cardiac hypertrophy and fibrosis in Angiotensin II-infused C57BL/6 mice

Olivares-Silva, Francisco; De Gregorio, Nicole; Sánchez-Ferrer, Carlos; Díaz-Araya Guillermo

ConferencePoster
 (2019)

Resolvin D1 decreases ICAM-1 and VCAM-1 expression on cardiac fibrolasts, induced by heparan sulfate

Velarde Víctor; Olivares-Silva, Francisco; Díaz-Araya Guillermo

ConferencePoster
 (2017)

Heparan sulfate increases leukocytes adhesion to cardiac fibroblasts through the TLR4 receptor

Olivares-Silva, Francisco; Anfossi Renato; Osorio José; Muñoz, Claudia; Bolívar Samir; Humeres, Claudio; Díaz-Araya Guillermo

ConferencePoster
 (2016)

9
Francisco Olivares

Pharmacology PhD(c)

Department of Pharmaceutical and Toxicological Chemistry

Universidad de Chile

Santiago, Chile

4
Claudia Muñoz

Postdoctorado

Universidad de Chile

Santiago, Chile

4
Renatto Anfossi

Coordinador de Investigación

Unidad de Investigación

Hospital Regional Libertador Bernardo O'Higgins

Rancagua, Chile

4
Guillermo Díaz

Académico

Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

3
Raúl Vivar

Profesor Asistente

Universidad de Chile

Santiago, Chile

1
Viviana Pardo

Profesional docente

Química Farmacológica y Toxicológica

Universidad de Chile

Santiago, Chile

1
Pablo Aránguiz

Postdoctorado

Fisiología y Biofísica

Universidad de Chile

Santiago, Chile