Systemic vasculitis associated with Fasciola hepatica infection

Llanos, C.; Soto L.; Sabugo, F; Gallegos I.; Valenzuela, O; Verdaguer J.; Cuchacovich M.

Abstract

We report the case of a 50-year-old man who presented with systemic vasculitis associated with Fasciola hepatica infection. The patient presented with severe skin, kidney, spleen, ophthalmic, and neurological compromise. An immunological examination for primary vasculitis was negative and other infections were discounted by microbiological and serological analyses. The patient was treated with steroids without clinical response. The Fasciola hepatica infection was confirmed by the presence of specific immunoglobulin G (IgG) serum antibodies detected by a quantitative enzyme-linked immunosorbent assay (ELISA) with an optical density (OD) of 0.483 OD units (normal value <0.170 OD units) and a high-titre complement fixation (1/80 dilution). The patient received treatment with triclabendazole and all symptoms and systemic manifestations resolved within weeks. Hence, this previously unreported vasculitis-associated infection, if identified opportunely, can be treated and cured. © 2006 Taylor & Francis on license from Scandinavian Rheumatology Research Foundation.

Más información

Título según WOS: Systemic vasculitis associated with Fasciola hepatica infection
Título según SCOPUS: Systemic vasculitis associated with Fasciola hepatica infection
Título de la Revista: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
Volumen: 35
Asunto: 2
Editorial: TAYLOR & FRANCIS LTD
Fecha de publicación: 2006-01-01
Página de inicio: 143
Página final: 146
Idioma: English
DOI/URL:

10.1080/03009740500303231

Identificador: 10.1080/03009740500303231
Notas: ISI, SCOPUS