Mesenchymal stem cells-secretome provides protection in neonatal hypoxia-reoxygenation. Mechanisms and translational studies

Morales, Paola; Herrera-Marschitz, Mario; Ezquer, Fernando; Quintanilla, Maria Elena; Israel, Yedy.; Valdés, José Luis

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Fecha de publicación: 2019
Año de Inicio/Término: 2019-2022
Financiamiento/Sponsor: CONICYT-FONDECYT
URL: https://post.conicyt.cl/frontend.php/es/version/5b8d4233d64ab9385570c270.html?date=1551286178.467
DOI:

ID:Fondecyt 1190562

Notas: The aim of this study is to determine whether the administration of preconditioned human MSC-secretome activates the Nrf2 and the ALDH2 pathways, reducing oxidative stress, neuroinflammation and cell death, preventing the motor, behavioral and cognitive disabilities induced by perinatal asphyxia.