Man

Susan Marcela Bueno Ramirez

Profesor Asociado

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Líneas de Investigación


Enfermedades infecciosas; Microbiología; Inmunologia; Microbiota; Métodos de diagnóstico; Probióticos; Neumonía; Microorganismos Patógenos; Interacción hospedero-patógeno; Genética molecular; Vacunas; Transferencia lateral de genes; Inflamación

Educación

  •  Licenciado en Tecnología Médica, Universidad de Chile. Chile, 1999
  •  Tecnólogo Médico, Mención Laboratorio Clínico, Banco de Sangre y Hematología, Universidad de Chile. Chile, 1999
  •  Doctor en Ciencias Biomédicas, Universidad de Chile. Chile, 2004

Experiencia Académica

  •   Profesor Asistente Full Time

    Pontificia Universidad Católica de Chile

    Ciencias Biológicas

    Santiago, Chile

    2007 - 2013

  •   Profesor Asociado Full Time

    Pontificia Universidad Católica de Chile

    Ciencias Biológicas

    Santiago, Chile

    2013 - 2021

  •   Profesor Visitante Other

    Universidad de Nantes

    Nantes, Francia

    2013 - A la fecha

  •   Adjunct Associate Research Professor of Microbiology & Immunology Other

    INDIANA UNIVERSITY

    Facultad de Medicina de South Bend

    South Bend, Estados Unidos

    2020 - A la fecha

  •   Profesora Titular Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Facultad de Ciencias Biológicas

    Santiago, Chile

    2021 - A la fecha

  •   Investigadora Visitante Other

    NEW YORK UNIVERSITY

    New York, Estados Unidos

    2010 - 2010

  •   Entrenamiento Postdoctoral (Visitante) Other

    ALBERT EINSTEIN COLLEGE OF MEDICINE

    Bronx, Estados Unidos

    2005 - 2005

  •   Profesor Titular Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Ciencias Biológicas

    Santiago, Chile

    2021 - A la fecha

  •   Profesora asociada adjunta de investigación en microbiología e inmunología Part Time

    INDIANA UNIVERSITY

    Indiana, Estados Unidos

    2020 - A la fecha

Experiencia Profesional

  •   Posdoctoral Internship Full Time

    Albert Einstein College of Medicine

    New York, Estados Unidos

    2005 - 2005

  •   Visiting Research Full Time

    Albert Einstein College of Medicine

    New York, Estados Unidos

    2008 - 2009

  •   Visiting Research Full Time

    New York University

    New York, Estados Unidos

    2010 - 2010

  •   Posdoctoral Researcher Full Time

    Pontificia Universidad Católica de Chile

    Santiago, Chile

    2004 - 2007

Formación de Capital Humano


Undergraduate and Master thesis
- Daniela Araya, Pontificia Universidad Católica de Chile, Research Unit BIO296 to obtain the licentiate degree in Biology (completed in August 2009).
- Rodrigo Lizana, Universidad Andrés Bello, thesis to obtain the degree of Master of Biochemistry (completed in March 2010).
- Tania Quiroz, Universidad de Santiago, thesis on Biochemistry (completed in May 2010).
- Daniela Pizarro, Pontificia Universidad Católica de Chile, Research Unit BIO296 to obtain the degree of Biologist (completed in August 2011).
- Francisco Javier Salazar Echegarai, Master's Degree candidate, Universidad de Chile (Graduation date July 2014)
- Abner Espinoza, Research Unit BIO296 to obtain the licentiate degree in Biology (completed in December 2011). Pontificia Universidad Católica de Chile
- Valentina Sebastián, Research Unit BIO296 to obtain the licentiate degree in Biology (Graduation date August 2012). Pontificia Universidad Católica de Chile
- Hernán Peñaloza, Research Unit BIO296 to obtain the licentiate degree in Biology (Graduation date December 2012). Pontificia Universidad Católica de Chile
- Geraldyne Salazar, Thesis on Biochemistry (Graduation date August 2015). Universidad de Valparaíso.
- Bárbara Schultz, Research Unit BIO296 to obtain the licentiate degree in Biology (Graduation date December 2012). Pontificia Universidad Católica de Chile
- Carolina Paduro, Research Unit BIO296 to obtain the licentiate degree in Biology. Title: Evaluación del efecto de la inmunización de ratones IL-10-/con cepas mutantes de Salmonella Typhimurium en el inicio y severidad de IBD. Research Unit finished in December 2014. Pontificia Universidad Católica de Chile
- Isidora Suazo, Research Unit BIO296 to obtain the licentiate degree in Biology. Title: “Role of IL-10 in the early inflammatory response of the central nervous system against infection with Streptococcus pneumoniae”. Research Unit finished in July 2015. Pontificia Universidad Católica de Chile
- Lorena Navarrete, Research Unit BIO296 to obtain the licentiate degree in Biology. Title: Frequency of excision of ROD21 during phases of growth in vitro of Salmonella Enteritidis. Research Unit finished in July 2015. Pontificia Universidad Católica de Chile
- Omar Vallejos, Research Unit BIO296 to obtain the licentiate degree in Biology. Title: Role of the enzyme Hemoxygenase-1 in the severity of infection caused by Salmonella enterica serovar Typhimurium. Research Unit Finished, December 2016. Pontificia Universidad Católica de Chile
- Loreani Noguera, Research Unit BIO296 to obtain the licentiate degree in Biochemistry. Title: Role of SEN1993 protein in the excision of pathogenicity island ROD21 in Salmonella. Research Unit Finished, December 2016. Pontificia Universidad Católica de Chile
- Diego Ulloa, Research Unit BIO296 to obtain the licentiate degree in Biology. Title: Búsqueda de elementos genéticos móviles posiblemente asociados a la virulencia de Klebsiella pneumoniae ST258. Research Unit finished in July 2017. Pontificia Universidad Católica de Chile
- Fernanda Balmaceda, Research Unit BIO296 to obtain the licentiate degree in Biochemistry. Title: Induction of interleukin 10 in neutrophils by Salmonella Typhimurium. Research Unit finished in July 2018. Pontificia Universidad Católica de Chile
-Loreani Noguera, Thesis to obtain the degree of Biochemist. Title: Characterization of host adaptation in Gram positive bacteria of clinical importance: Staphylococcus aureus and Streptococcus pneumoniae. Graduation date March 2019. Pontificia Universidad Católica de Chile
- Pedro Silva, Thesis to obtain the degree of Biochemist. Characterization of Salmonella enterica serovar Typhimurium dissemination in a double KO Tmem176a and Tmem176b murine model. Graduation date August 2019. Pontificia Universidad Católica de Chile
- Daniela Moreno, Research Unit BIO296 to obtain the licentiate degree in Biochemistry. Title: Standardization of an in vitro model of persistence of Salmonella Typhimurium in macrophages. Research Unit finished in December 2019. Pontificia Universidad Católica de Chile
- Guillermo Hoppe, Research Unit BIO296 to obtain the licentiate degree in Biochemistry. Title: In silico characterization of the gene backbone and encoded proteins of Enterobacteriaceae-associated ROD21-like genomic islands. Research Unit finished in December 2020. Pontificia Universidad Católica de Chile.
- Daniela Moreno, Thesis to obtain the degree of Biochemist. Title: In vitro evaluation of survival of Salmonella enterica serovar Typhimurium in RAW264.7 cells against different treatments that modulate heme oxygenase-1 activity. Graduation date: August 2021. Pontificia Universidad Católica de Chile.
- Guillermo Hoppe, Thesis to obtain the degree of Biochemist. Title: Characterization of SEN1990, a putative transcriptional regulator from the MarR family encoded in the pathogenicity island ROD21. Graduation date: Pending. Pontificia Universidad Católica de Chile.
- Francisca Román, Research Unit BIO296 to obtain the licentiate degree in Biochemistry. Title: Evaluation of the role of MDSC in infection with human metapneumovirus. Research Unit finished in June 2021. Pontificia Universidad Católica de Chile.
- Javiera Sepúlveda, Research Unit BIO296 to obtain the licentiate degree in Biochemistry. Title: Effect of gut microbiota dysbiosis on the severity of hMPV infection in the lung. Research Unit finished in December 2021. Pontificia Universidad Católica de Chile.
- Eduardo Catalán, Research Unit BIO296 to obtain the licentiate degree in Biology. Title: Evaluation of the effects of respiratory tract infection with metapneumovirus on the microbiota. Research Unit finished in June 2022. Pontificia Universidad Católica de Chile.
- Pablo Reyes, Research Unit BIO296 to obtain the licentiate degree in Biochemistry. Title: Characterization of chuS expression and its relationship with carbon monoxide release in Escherichia coli Nissle 1917. Research Unit finished in December 2022. Pontificia Universidad Católica de Chile.
- Yohana Martínez, Research Unit BIO296 to obtain the licentiate degree in Biochemistry. Title: Characterization of the humoral and cellular immune response in mice immunized with recombinant RBD peptides from the Omicron variant of SARS-CoV-2. Research Unit finished in December 2022. Pontificia Universidad Católica de Chile.
- Sofía Campos, Research Unit BIO296 to obtain the licentiate degree in Biology. Title: Evaluation of the anti-inflammatory potential of acetic acid bacteria isolated from Chilean apple cider vinegar. Research Unit finished in December 2022. Pontificia Universidad Católica de Chile.
- Valentina Scaff, Research Unit BIO296 to obtain the licentiate degree in Biochemistry. Title: Inflammatory bowel disease course: RhoA/RHO kinase as a key player in the interplay between vitamin D status and both gut endothelial dysfunction and intestinal microbiota. Research Unit finished in December 2022. Pontificia Universidad Católica de Chile.
- Franco Bassi, Research Unit BIO296 to obtain the licentiate degree in Biochemistry. Title: Evaluation of the safety and protection of an attenuated bacterial vaccine against an infection caused by Salmonella enterica serovar Enteritidis in a mouse model. Research Unit finished in December 2022. Pontificia Universidad Católica de Chile.
- Camila Pardo, Research Unit BIO296 to obtain the licentiate degree in Biology. Title: Salmonella enterica serovars Typhimurium and Enteritidis induce differential release of METs from macrophages. Research Unit finished in December 2022. Pontificia Universidad Católica de Chile.
- María José Cristi, Research Unit BIO296 to obtain the licentiate degree in Biology. Title: Evaluation of the formation of NETs by the gasdermin pathway by infection of two serovars of Salmonella enterica. Research Unit finished in December 2022. Pontificia Universidad Católica de Chile.
- Tomás González, Research Unit BIO296 to obtain the licentiate degree in Biology. Title: Role of IL-17A in secondary viral infections. Research Unit finished in December 2022. Pontificia Universidad Católica de Chile.
- Matías Cuevas, Research Unit BIO296 to obtain the licentiate degree in Biology. Title: Contribution of the SOS response on the excision of the ROD21 pathogenicity island of Salmonella enterica serovar Enteritidis. Research Unit finished in December 2022. Pontificia Universidad Católica de Chile.
- Javiera Sepúlveda, Thesis to obtain the degree of Biochemist. Title: Evaluation of the effects of respiratory tract infection with metapneumovirus on the microbiota and intestinal inflammation in early and late stages. Graduation date: April 2023. Pontificia Universidad Católica de Chile.
- Francisca Román, Thesis to obtain the degree of Biochemist. Title: Analysis of the conservation in Spike protein sequences in SARS-CoV-2 variants and their relevance for universal immunization against the virus. Graduation date: September 2023. Pontificia Universidad Católica de Chile.
- Lucas Vásquez, Unit BIO296 to obtain the licentiate degree in Biochemistry. Title: Construction of a mutant strain Salmonella enterica serovar Enteritidis PT4 ?ROD21 and determination of its effect on bacterial growth and plasmid maintenance. Research Unit finished in December 2023. Pontificia Universidad Católica de Chile.
- Allison Salazar, Unit BIO296 to obtain the licentiate degree in Biology. Title: Correlation between thyroid hormone levels and the immune response after CoronaVac® vaccination. Research Unit finished in December 2023. Pontificia Universidad Católica de Chile.
- Pascal Salas, Unit BIO296 to obtain the licentiate degree in Biochemistry. Title: Utilizing CRISPR/Cas9 system for PmrA gene deletion in Klebsiella pneumoniae and Gibson Assembly for pUC19_?aroA plasmid construction. Research Unit finished in December 2023. Pontificia Universidad Católica de Chile.
- Pablo Reyes, Thesis to obtain the degree of Biochemist. Title: Evaluation of ChuS’ impact on Escherichia coli Nissle 1917’s ability to reduce inflammation in the context of inflammatory bowel disease. Graduation date: Pending. Pontificia Universidad Católica de Chile.
- Franco Bassi, Thesis to obtain the degree of Biochemist. Title: Evaluation of a potential live attenuated vaccine candidate against Salmonella enterica serovar Enteritidis in a murine model. Graduation date: Pending. Pontificia Universidad Católica de Chile.
- Valentina Scaff, Thesis to obtain the degree of Biochemist. Title: Evaluation of dietary supplementation with vitamin D for reducing inflammation in inflammatory bowel diseases. Graduation date: Pending. Pontificia Universidad Católica de Chile.

PhD thesis
- Hugo Tobar, thesis to obtain the degree of PhD in Biological Sciences, major in Molecular Genetics and Microbiology, Pontificia Universidad Católica de Chile (qualify exam approved in September 2009. Thesis title: “Escisión de la Isla de Patogenicidad ROD21 y su impacto en la virulencia de Salmonella enterica serovar Enteritidis”. Graduated, December 2012.
- Sebastián Riquelme, thesis to obtain the degree of PhD in Biological Sciences, major in Molecular Genetics and Microbiology, Pontificia Universidad Católica de Chile. Thesis title: “The role of the carbon monoxide-producing enzyme heme-oxygenase 1 in the immunogenicity of dendritic cells”. Graduated, August 2015.
- Pamela Nieto, thesis to obtain the degree of PhD in Biological Sciences, major in Molecular Genetics and Microbiology, Pontificia Universidad Católica de Chile. Qualify exam approved in August 2011. Thesis title: ‘‘Thyroid hormone deficiency during pregnancy and its effects on the T cell response against a Streptococcus pneumoniae infection in the offspring’’. Graduated, November 2015.
- Catalina Pardo-Roa, thesis to obtain the degree of PhD in Biological Sciences, major in Molecular Genetics and Microbiology, Pontificia Universidad Católica de Chile. Qualify exam approved in April 2015. Thesis title: “in vivo evaluation of unstable ROD21 pathogenicity island excision of Salmonella Enteritidis in the regulation of its genes expression during different stages of the infection cycle”. Graduated, July 2018.
- Hernán Peñaloza, thesis to obtain the degree of PhD in Biological Sciences, major in Molecular Genetics and Microbiology, Pontificia Universidad Católica de Chile. Qualify exam approved in June 4th, 2015. Thesis title: “Neutrophils contribution to the modulation of the airways immune response at early stage of bacterial infection”. Graduated, August 2018.
- Loni Berkowitz, thesis to obtain the degree of PhD in Medical Sciences, School of Medicine, Pontificia Universidad Católica de Chile. Qualify exam approved in October 3th, 2015. Thesis title: “Effect of cigarette smoking on the functionality of Paneth cells and their importance in the development and progression of Crohn's Disease”. Graduated, November 2018.
- Valentina Sebastian, thesis to obtain the degree of PhD in Biological Sciences, major in Molecular Genetics and Microbiology, Pontificia Universidad Católica de Chile. Qualify exam approved in June 4th, 2015. Thesis title: “Heme Oxygenase 1 (HMOX1) contribution to modulating the severity of Salmonella enterica serovar Typhimurium infection in mice”. Graduated, December 2019.
- Irenice Coronado, thesis to obtain the degree of PhD in Biological Sciences, major in Molecular Genetics and Microbiology, Pontificia Universidad Católica de Chile. Qualify exam approved in June 2nd, 2015. Thesis title: “Characterization of bacterial heme oxygenase ChuS of probiotic strain E. coli Nissle 1917 and its potential therapeutic uses”. Graduated, April 2020.
- Liliana González, thesis to obtain the degree of PhD in Biological Sciences, major in Molecular Genetics and Microbiology, Pontificia Universidad Católica de Chile. Qualify exam approved in October 24th, 2017. Thesis title: “Evaluation of the ability of neutrophils to induce anti-inflammatory responses in the airways through the recognition of molecular patterns of Streptococcus pneumoniae”. Thesis project in progress. Estimated date of thesis defense: August 2020.
- Bárbara Schultz, thesis to obtain the degree of PhD in Biological Sciences, major in Molecular Genetics and Microbiology, Pontificia Universidad Católica de Chile. Qualify exam approved in June 28th, 2017. Thesis title: “Role of Ly6G+ cell during systemic infection caused by Salmonella enterica serovar Typhimurium in mice”. Thesis project in progress. Estimated date of thesis defense: December 2020.
- Alejandro Piña, thesis to obtain the degree of PhD in Biological Sciences, major in Molecular Genetics and Microbiology, Pontificia Universidad Católica de Chile. Qualify exam approved in June 14th, 2017. Thesis title: “Chromosomal Excision Regulation of the Salmonella enterica serovar Enteritidis Pathogenicity Island ROD21”. Thesis project in progress. Estimated date of thesis defense: December 2020.
- Orlando Acevedo, thesis to obtain the degree of PhD in Biological Sciences, major in Molecular Genetics and Microbiology, Pontificia Universidad Católica de Chile. Qualify exam approved in August 8th, 2017. Thesis title: “Contribution of Fc gamma receptor III to immunity against respiratory infectious agents”. Thesis project in progress. Estimated date of thesis defense: December 2020.
- Isidora Suazo, thesis to obtain the degree of PhD in Biological Sciences, major in Molecular Genetics and Microbiology, Pontificia Universidad Católica de Chile. Qualify exam approved in August 7th, 2019. Thesis title: ‘‘Virulence regulation in Salmonella enterica serovar Enteritidis by pathogenicity island excision’’. Estimated date of thesis defense: December 2022.
- Pedro Silva, thesis to obtain the degree of PhD in Biological Sciences, major in Physiology, Pontificia Universidad Católica de Chile. Qualify exam approved on August 13th, 2021. Thesis title: ‘‘Characterization of neutrophil subpopulations produced in response to Streptococcus pneumoniae infection in a murine model’’. Estimated date of thesis defense: December 2024.
- Omar Vallejos, thesis to obtain the degree of PhD in Biological Sciences, major in Molecular Genetics and Microbiology, Pontificia Universidad Católica de Chile. Qualify exam: pending. Thesis title: ‘‘ Development of a probiotic bacterial formulation with anti-inflammatory properties to prevent and treat inflammatory, autoimmune and infectious diseases’’. Estimated date of thesis defense: December 2026.


Difusión y Transferencia


-Organización Actividad de Proyección al Medio Externo: Ciclo de Cine Científico con la película Epidemia, 4 funciones para alumnos de 4to medio (aproximadamente 535 estudiantes y profesores), Pontificia Universidad Católica de Chile, Instituto Milenio de Inmunología e Inmunoterapia. 20 y 21 de agosto del 2015, Quintero – Chile.
-Organización Actividad de Proyección al Medio Externo: Ciclo de Cine Científico con la película Epidemia, 3 funciones para alumnos de 4to medio (aproximadamente 350 estudiantes y profesores), Pontificia Universidad Católica de Chile, Instituto Milenio de Inmunología e Inmunoterapia. 2 y 3 de noviembre del 2015, Antofagasta – Chile.
-Organización Actividad de Proyección al Medio Externo: Ciclo de Charlas Científicas: Agente Infecciosos y Sistema Inmune para alumnos de 3ro y 4to medio (aproximadamente 100 estudiantes y profesores), Liceo Andrés Sabella, Pontificia Universidad Católica de Chile, Instituto Milenio de Inmunología e Inmunoterapia. 4 de noviembre del 2015, Antofagasta, Chile.
-Participación en X Fiesta de la Ciencia y la Tecnología de EXPLORA, Stand del Laboratorio de Patogénesis Microbiana, Octubre 2016 en el Museo Interactivo Mirador, Santiago, Chile.
-Participación en XI Fiesta de la Ciencia y la Tecnología de EXPLORA, Encargado Stand del Laboratorio de Patogénesis Microbiana, Octubre 2017 en el Parque Metropolitano, Santiago, Chile.
-Charla sobre Vacunas en Escuela Municipal Violeta Parra de La Pintana. 14 de Noviembre de 2018.
-Charla “Equilibrio entre el Intestino y Sistema Inmune: Rol de los microorganismos”, Bloque “Conciencia del cuerpo”, Congreso Futuro 2018, Santiago, Chile. https://www.youtube.com/watch?v=koGvo-rZ9wQ
-Participación en XII Fiesta de la Ciencia y la Tecnología de EXPLORA, Encargado del Stand del Laboratorio de Patogénesis Microbiana, Octubre 2018 en el Parque Metropolitano, Santiago, Chile.
-Participación en bloque “Guatita llena, corazón contento” Programa “Por la Razón y la Ciencia”, 2019 (https://www.youtube.com/watch?v=PFDIgogLvsQ).
-Organización Ciclo Cine Científico 2019. Exhibición de películas “Food as Medicine” y “Contagio”. 22 y 23 de Julio del 2019, Cine Centro de Extensión, Pontificia Universidad Católica de Chile.
-Participación en Mesa de conversación: Corazón de lechuga – Feria de Autores de Santiago (FAS). 28 de Septiembre del 2019. Centro Cultural Gabriela Mistral, Santiago, Chile.
-Participación en XIII Fiesta de la Ciencia y la Tecnología de EXPLORA, Encargado del Stand del Laboratorio de Patogénesis Microbiana, Octubre 2019 en el Parque Metropolitano, Santiago, Chile.


Premios y Distinciones

  •   Country Liaison to Chile

    American Society of Microbiology

    Estados Unidos, 2011

    N/A

  •   Premio Nacional de Innovación Avonni categoría Salud

    Foro Innovación

    Chile, 2018

    N/A

  •   Premio al Patentamiento. II Concurso de Propiedad Intelectual

    Pontificia Universidad Católica de Chile

    Chile, 2010

    N/A

  •   Premio a la mejor tesis de Tecnología Médica, Mención Bioanálisis Clínico, Hematología y Banco de Sangre

    Universidad de Chile

    Chile, 1998

    N/A

  •   Tercer lugar en II Concurso de Inventos Patentados PROSUR (Patente Anticuerpos monoclonales anti-Virus Respiratorio Sincicial)

    PROSUR / INAPI-Chile / OMPI

    Chile, 2019

    Propiedad Industrial Latinoamericana (PROSUR), Instituto Nacional de Propiedad Intelectual (INAPI-Chile) y Organización Mundial de la Propiedad Intelectual (OMPI)

  •   Nombramiento Adjunct Associate Research Professor of Microbiology & Immunology

    Escuela de Medicina en South Bend, Universidad de Indiana

    Estados Unidos, 2020

    N/A

  •   Premio 100 Mujeres Líderes 2020, Categoría Salud

    DIARIO EL MERCURIO

    Chile, 2020

    Premio 100 Mujeres Líderes 2020, Categoría Salud

  •   2020 Women Leaders in Health Award

    Global Health Chile

    Chile, 2020

    Premio Mujeres Líderes en Salud 2020

  •   Protagonista 2030

    DIARIO EL MERCURIO

    Chile, 2021

    2030 Protagonist

  •   Expertscape World Expert in Pneumovirinae

    Expertscape

    Chile, 2021

    Expertscape World Expert in Pneumovirinae

  •   Mujer en I+D e Innovación 2022

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2023

    Mujer en I+D e Innovación 2022. Dirección de Transferencia y Desarrollo, Vicerrectoría de Investigación, Pontificia Universidad Católica de Chile


 

Article (148)

Differential Severe Acute Respiratory Syndrome Coronavirus 2-Specific Humoral Response in Inactivated Virus-Vaccinated, Convalescent, and Breakthrough-Infected Subjects
Gut microbiota short-chain fatty acids and their impact on the host thyroid function and diseases
Heme Oxygenase-1 Expression in Dendritic Cells Contributes to Protective Immunity against Herpes Simplex Virus Skin Infection
Humoral and cellular response induced by a second booster of an inactivated SARS-CoV-2 vaccine in adults
Impact of homologous and heterologous boosters in neutralizing antibodies titers against SARS-CoV-2 Omicron in solid-organ transplant recipients
Is there a role for herpes simplex virus type 1 in multiple sclerosis?
New Developments and Challenges in Antibody-Based Therapies for the Respiratory Syncytial Virus
Novel evidence on sepsis-inducing pathogens: from laboratory to bedside
SEN1990 is a predicted winged helix-turn-helix protein involved in the pathogenicity of <i>Salmonella enterica</i> serovar Enteritidis and the expression of the gene <i>oafB</i> in the SPI-17
A Booster Dose of CoronaVac Increases Neutralizing Antibodies and T Cells that Recognize Delta and Omicron Variants of Concern
BCG vaccination induces cross-protective immunity against pathogenic microorganisms
BCG-Based Vaccines Elicit Antigen-Specific Adaptive and Trained Immunity against SARS-CoV-2 and Andes orthohantavirus
Bioinformatic and experimental characterization of SEN1998: a conserved gene carried by the Enterobacteriaceae-associated ROD21-like family of genomic islands
Differences in the immune response elicited by two immunization schedules with an inactivated SARS-CoV-2 vaccine in a randomized phase 3 clinical trial
Distal Consequences of Mucosal Infections in Intestinal and Lung Inflammation
Identification of biomarkers for disease severity in nasopharyngeal secretions of infants with upper or lower respiratory tract viral infections
Inactivated Vaccine-Induced SARS-CoV-2 Variant-Specific Immunity in Children
Increased Heme Oxygenase 1 Expression upon a Primary Exposure to the Respiratory Syncytial Virus and a Secondary Mycobacterium bovis Infection
Limited Heme Oxygenase Contribution to Modulating the Severity of Salmonella enterica serovar Typhimurium Infection
Modulation of Immune Cells as a Therapy for Cutaneous Lupus Erythematosus
Non-capsular based immunization approaches to prevent Streptococcus pneumoniae infection
Pharmacological Inhibition of IRE-1 Alpha Activity in Herpes Simplex Virus Type 1 and Type 2-Infected Dendritic Cells Enhances T Cell Activation
Reduced Immune Response to Inactivated Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine in a Cohort of Immunocompromised Patients in Chile
Safety and Non-Inferiority Evaluation of Two Immunization Schedules with an Inactivated SARS-CoV-2 Vaccine in Adults: A Randomized Clinical Trial
SARS-CoV-2 vaccine booster in solid organ transplant recipients previously immunised with inactivated versus mRNA vaccines: A prospective cohort study
Activation of regulator ArcA in the presence of hypochlorite in Salmonella enterica serovar Typhimurium
Asymptomatic Herpes Simplex Virus Type 1 Infection Causes an Earlier Onset and More Severe Experimental Autoimmune Encephalomyelitis
Characterization of the Anti-Inflammatory Capacity of IL-10-Producing Neutrophils in Response to Streptococcus pneumoniae Infection
Crosstalk Between Epithelial Cells, Neurons and Immune Mediators in HSV-1 Skin Infection
Effective Treatment against ESBL-Producing Klebsiella pneumoniae through Synergism of the Photodynamic Activity of Re (I) Compounds with Beta-Lactams
IL-10-Dependent Amelioration of Chronic Inflammatory Disease by Microdose Subcutaneous Delivery of a Prototypic Immunoregulatory Small Molecule
Immune Profile and Clinical Outcome of Breakthrough Cases After Vaccination With an Inactivated SARS-CoV-2 Vaccine
Induction of Protective Immunity by a Single Low Dose of a Master Cell Bank cGMP-rBCG-P Vaccine Against the Human Metapneumovirus in Mice
Modulation of Endosome Function, Vesicle Trafficking and Autophagy by Human Herpesviruses
New Insights on the Early Interaction Between Typhoid and Non-typhoid Salmonella Serovars and the Host Cells
Recognition of Variants of Concern by Antibodies and T Cells Induced by a SARS-CoV-2 Inactivated Vaccine
Safety and Immunogenicity of an Inactivated Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine in a Subgroup of Healthy Adults in Chile
Thyroid Gene Mutations in Pregnant and Breastfeeding Women Diagnosed With Transient Congenital Hypothyroidism: Implications for the Offspring's Health
Antibody development for preventing the human respiratory syncytial virus pathology
Contribution of hypoxia inducible factor-1 during viral infections
Could BCG Vaccination Induce Protective Trained Immunity for SARS-CoV-2?
Innate Immune Components That Regulate the Pathogenesis and Resolution of hRSV and hMPV Infections
L-Arginine Enhances Intracellular Killing of Carbapenem-Resistant Klebsiella pneumoniae ST258 by Murine Neutrophils
Naturally Derived Heme-Oxygenase 1 Inducers and Their Therapeutic Application to Immune-Mediated Diseases
Pharmacological management of human respiratory syncytial virus infection
Safety and immunogenicity evaluation of recombinant BCG vaccine against respiratory syncytial virus in a randomized, double-blind, placebo-controlled phase I clinical trial
The impact of the micronutrient iodine in health and diseases
The Role of Dendritic Cells During Infections Caused by Highly Prevalent Viruses
Cytokines in the Respiratory Airway as Biomarkers of Severity and Prognosis for Respiratory Syncytial Virus Infection: An Update
Interleukin-10 Produced by Myeloid-Derived Suppressor Cells Provides Protection to Carbapenem-Resistant Klebsiella pneumoniae Sequence Type 258 by Enhancing Its Clearance in the Airways
Mucosal Exposure to Cigarette Components Induces Intestinal Inflammation and Alters Antimicrobial Response in Mice
Pathogenicity island excision during an infection by Salmonella enterica serovar Enteritidis is required for crossing the intestinal epithelial barrier in mice to cause systemic infection
The absence of interleukin 10 affects the morphology, differentiation, granule content and the production of cryptidin-4 in Paneth cells in mice
THE OFFSPRING GESTATED IN HYPOTHYROXINEMIA HAS HIGHER PARACELLULAR INTESTINAL PERMEABILITY AND SIGNS OF INTESTINAL INFLAMMATION
Assessing the Importance of Domestic Vaccine Manufacturing Centers=> An Overview of Immunization Programs, Vaccine Manufacture, and Distribution.
Clinical and microbiological response of mice to intranasal inoculation with Lactococcus lactis expressing Group A Streptococcus antigens, to be used as an anti-streptococcal vaccine
Comparative and phylogenetic analysis of a novel family of Enterobacteriaceae-associated genomic islands that share a conserved excision/integration module.
Evaluation of monoclonal antibodies that detect conserved proteins from Respiratory Syncytial Virus, Metapneumovirus and Adenovirus in human samples.
Gestational Hypothyroxinemia Affects Its Offspring With a Reduced Suppressive Capacity Impairing the Outcome of the Experimental Autoimmune Encephalomyelitis.
Gestational Hypothyroxinemia Imprints a Switch in the Capacity of Astrocytes and Microglial Cells of the Offspring to React in Inflammation.
Impact of Cigarette Smoking on the Gastrointestinal Tract Inflammation=> Opposing Effects in Crohn's Disease and Ulcerative Colitis.
Interleukin 10 modulation of neutrophil subsets infiltrating lungs during infection.
Patterns of antibody response during natural hRSV infection=> insights for the development of new antibody-based therapies.
Persistent serovar Typhimurium Infection Increases the Susceptibility of Mice to Develop Intestinal Inflammation.
Protective immunity induced by an intranasal multivalent vaccine comprising 10 Lactococcus lactis strains expressing highly prevalent M-protein antigens derived from Group A Streptococcus
Recombinant BCG Vaccines Reduce Pneumovirus-Caused Airway Pathology by Inducing Protective Humoral Immunity
The role of myeloid-derived suppressor cells in chronic infectious diseases and the current methodology available for their study
Gene Deletion in Herpes Simplex Virus Type 2 Enhances Dendritic Cell Function and T Cell Activation.
A Herpes Simplex Virus Type 2 Deleted for Glycoprotein D Enables Dendritic Cells to Activate CD4 and CD8 T Cells.
A Potential Role of Infection in the Onset of Inflammatory Bowel Diseases.
A Potential Role of Salmonella Infection in the Onset of Inflammatory Bowel Diseases
A single, low dose of a cGMP recombinant BCG vaccine elicits protective T cell immunity against the human respiratory syncytial virus infection and prevents lung pathology in mice.
Aberrant T cell immunity triggered by human Respiratory Syncytial Virus and human Metapneumovirus infection.
Heme Oxygenase-1 Modulates Human Respiratory Syncytial Virus Replication and Lung Pathogenesis during Infection.
Imprinting of maternal thyroid hormones in the offspring
Innate immune cells for immunotherapy of autoimmune and cancer disorders.
Interleukin-10 Production by T and B Cells Is a Key Factor to Promote Systemic Serovar Typhimurium Infection in Mice.
Modulating the function of the immune system by thyroid hormones and thyrotropin.
Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors=> A Synergic Inhibition of Both Innate and Adaptive Immunity.
Acquired resistance to innate immune clearance promotes Klebsiella pneumoniae ST258 pulmonary infection
Gestational hypothyroidism improves the ability of the female offspring to clear streptococcus pneumoniae infection and to recover from pneumococcal pneumonia
Gestational Hypothyroxinemia Affects Glutamatergic Synaptic Protein Distribution and Neuronal Plasticity Through Neuron-Astrocyte Interplay.
Human Respiratory Syncytial Virus: Infection and Pathology.
Human Respiratory Syncytial Virus=> Infection and Pathology.
Immune Evasion by Herpes Simplex Viruses
Modulation of antigen processing by haem-oxygenase 1. Implications on inflammation and tolerance.
Modulation of Host Immunity by the Human Metapneumovirus.
Modulation of Host Immunity by the Human Metapneumovirus.
Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling.
Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling.
New insights about excisable pathogenicity islands in Salmonella and their contribution to virulence.
New insights on the viral and host factors contributing to the airway pathogenesis caused by the respiratory syncytial virus.
New insights on the viral and host factors contributing to the airway pathogenesis caused by the respiratory syncytial virus.
Opposing roles of IL-10 in acute bacterial infection.
Opposing roles of IL-10 in acute bacterial infection.
Carbon monoxide down-modulates Toll-like receptor 4/MD2 expression on innate immune cells and reduces endotoxic shock susceptibility
Carbon monoxide impairs mitochondria-dependent endosomal maturation and antigen presentation in dendritic cells
Elevated IL-3 and IL-12p40 levels in the lower airway of infants with RSV-induced bronchiolitis correlate with recurrent wheezing
Excess Iodide Induces an Acute Inhibition of the Sodium/Iodide Symporter in Thyroid Male Rat Cells by Increasing Reactive Oxygen Species
Gestational Hypothyroxinemia Affects Glutamatergic Synaptic Protein Distribution and Neuronal Plasticity Through Neuron-Astrocyte Interplay
Human metapneumovirus infection activates the TSLP pathway that drives excessive pulmonary inflammation and viral replication in mice
Interleukin-10 plays a key role in the modulation of neutrophils recruitment and lung inflammation during infection by Streptococcus pneumoniae
Toxin-Induced Necroptosis Is a Major Mechanism of Staphylococcus aureus Lung Damage
Understanding Lung Immunopathology Caused by the Human Metapneumovirus: Implications for Rational Vaccine Design
A Novel Live Vector Group A Streptococcal emm Type 9 Vaccine Delivered Intranasally Protects Mice against Challenge Infection with emm Type 9 Group A Streptococci
Conjugal transfer of the pathogenicity island ROD21 in Salmonella enterica serovar Enteritidis depends on environmental conditions
Conjugal transfer of the pathogenicity island ROD21 in Salmonella enterica serovar Enteritidis depends on environmental conditions.
Heme oxygenase-1 as a target for the design of gene and pharmaceutical therapies for autoimmune diseases
Immunization with a Recombinant Bacillus Calmette-Guerin Strain Confers Protective Th1 Immunity against the Human Metapneumovirus
Induction of protective effector immunity to prevent pathogenesis caused by the respiratory syncytial virus. Implications on therapy and vaccine design.
Induction of protective effector immunity to prevent pathogenesis caused by the respiratory syncytialvirus. Implications on therapy and vaccine design
Modulation of host adaptive immunity by hRSV proteins
Respiratory syncytial virus detection in cells and clinical samples by using three new monoclonal antibodies
Secretion of IL-16 through TNFR1 and calpain-caspase signaling contributes to MRSA pneumonia
Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells
Carbon monoxide decreases endosome-lysosome fusion and inhibits soluble antigen presentation by dendritic cells to T cells
Chromosomal excision of a new pathogenicity island modulates salmonella virulence in vivo
Gestational Hypothyroidism Increases the Severity of Experimental Autoimmune Encephalomyelitis in Adult Offspring
Human metapneumovirus infection induces expression of thymic stromal lymphopoetin and IL-33 in airway epithelial cells in vitro and lung infiltration of OX40L+DCs in vivo
Impaired learning resulting from Respiratory Syncytial Virus infection
Role of Salmonella enterica exposure in Chilean Crohn's disease patients
Understanding Respiratory Syncytial Virus Infection to Improve Treatment and Immunity
Genotipo y fenotipo de la enzima tiopurina metiltransferasa en población chilena
Hypothyroidism in the Adult Rat Causes Incremental Changes in Brain-Derived Neurotrophic Factor, Neuronal and Astrocyte Apoptosis, Gliosis, and Deterioration of Postsynaptic Density
IgG keeps virulent Salmonella from evading dendritic cell uptake
Phenotype and genotype of thiopurine methyltransferase in Chilean individuals
Excision of an Unstable Pathogenicity Island in Salmonella enterica Serovar Enteritidis Is Induced during Infection of Phagocytic Cells
Modulation of the dendritic cell-T-cell synapse to promote pathogen immunity and prevent autoimmunity
Deletion of a prophage-like element causes attenuation of Salmonella enterica serovar Enteritidis and promotes protective immunity
Efficient Lung Recruitment of Respiratory Syncytial Virus-Specific Th1 Cells Induced by Recombinant Bacillus Calmette-Guerin Promotes Virus Clearance and Protects from Infection
MECANISMOS MOLECULARES UTILIZADOS POR SALMONELLA PARA CAUSAR INFECCIONES DEL TRACTO DIGESTIVO
Salmonella pathogenicity island 1 differentially modulates bacterial entry to dendritic and non-phagocytic cells
Altered Chemokine Receptor Expression in Papillary Thyroid Cancer
Modulation of nuclear factor-kappa B activity can influence the susceptibility to systemic lupus erythematosus
Host immunity during RSV pathogenesis
Maternal hypothyroxinemia impairs spatial learning and synaptic nature and function in the offspring
Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG
Respiratory syncytial virus impairs T cell activation by preventing synapse assembly with dendritic cells
The capacity of Salmonella to survive inside dendritic cells and prevent antigen presentation to T cells is host specific
The half-life of the T-cell receptor/peptide-major histocompatibility complex interaction can modulate T-cell activation in response to bacterial challenge
Virulent Salmonella enterica serovar typhimurium evades adaptive immunity by preventing dendritic cells from activating T cells
Precise excision of the large pathogenicity island, SP17, in Salmonella enterica serovar Typhi
Precise Excision of the Large Pathogenicity Island, SPI7, in Salmonella enterica Serovar Typhi
Aspects of the predicted physiology of Acidithiobacillus ferrooxidans deduced from an analysis of its partial genome sequence
The Salmonella enterica sv. Typhimurium smvA, yddG and ompD (porin) genes are required for the efficient efflux of methyl viologen
IST1 insertional inactivation of the resB gene: Implications for phenotypic switching in Thiobacillus ferrooxidans
The use of insertion sequences to analyse gene function in Thiobacillus ferrooxidans: A case study involving cytochrome c-type biogenesis proteins in iron oxidation
IgG prevents subversion of dendritic cell phagocytosis by virulent Salmonella and restores antigen presentation to T cells

Abstract (4)

Contribution of neutrophils to IL-10 production during pneumococcal pneumonia and its impact on disease progression
THE OFFSPRING GESTATED IN HYPOTHYROXINEMIA COUNT WITH LESS FUNCTIONAL TREG CELLS DUE TO CD25 LOCALIZES IN THE INTRACELLULAR INCREASING THEIR AUTOIMMUNE RESPONSE DURING EAE.
Molecular Mechanism Associated to the Offspring's Cognitive Impairment due to Maternal Thyroid Hormones Deficiency during Gestation
The capacity of Salmonella to escape from antigen presentation in dendritic cells is restricted by serovar-host specificity

BookWhole (3)

Medicina en tu Cocina
Manual de Microbiología
Microorganismos y Enfermedades

ConferencePoster (30)

Actividad intracelular de Salmonella enterica serovar Typhimurium en células fagocíticas de ratón IL-10-/-
Carbon monoxide decreases endosome-lysosome fusion and inhibits soluble antigen presentation by dendritic cells
Dilucidando el mecanismo de Transferencia genética horizontal de la isla de patogenicidad ROD21 de Salmonella Enteritidis
Escisión de elementos genéticos inestables en Salmonella durante la infección de células fagocíticas
Estudio de elementos genéticos inestables en el cromosoma de Salmonella
Evaluación de la frecuencia de pérdida de regiones Inestables en Salmonella enterica serovar Enteritidis
Evaluación del rol de la infección por Salmonella en el inicio y severidad de la enfermedad inflamatoria intestinal.
EXCISION OF AN UNSTABLE GENETIC ELEMENT OF SALMONELLA ENTERICA SEROVAR ENTERITIDIS DURING INFECTION
Gestational hypothyroidism in mice makes female offspring more resistant to pneumococcal pneumonia.
Identificación de una isla de patogenicidad inestable en el cromosoma de Salmonella enterica serovar Enteritidis
Immunity against Salmonella enterica serovar Enteritidis is promoted by a Salmonella strain lacking a prophage-like element
Immunization with a recombinant BCG strain confers protective Th1 immunity against the human metapneumovirus
Impaired learning resulting from RSV infection
Inducción de inmunidad anti-Salmonella en ratones mediante la vacunación oral con una cepa de S. Enteritidis carente de un profago serovar-específico
Pathogen array reveals innate immune defense against molecular mimicry
Production of IL-10 during a Streptococcus pneumoniae infection prevents excessive inflammation in lungs.
Protective Immunity Against Salmonella in Mice can be Promoted by an Attenuated Mutant Strain of S. Enteritidis Lacking sopE and sodC Genes
Regulación de la función y expresión del simporter Na+/I- (NIS) por Ioduro- en células tiroideas
ROD21: Una isla de patogenicidad inestable con múltiples formas de escisión
Rol de la citoquina antinflamatoria IL-10 in la habilidad de Salmonella entérica serovar Typhimurium para causar infección sistémica en ratones
Rol de la exposición a Salmonella en pacientes chilenos con enfermedad de Crohn.
Rol de la producción de IL-10 en la severidad de una infección por Streptococcus pneumoniae en ratones
Role of pathogenicity island excision in Salmonella enterica
Role of the Pathogenicity Islands Excision in Bacterial Virulence: ROD21 of Salmonella enterica Serovar Enteritidis as an Example
Salmonella interference with host immunity
Salmonella pathogenicity island 1 differentially modulates bacterial entry to dendritic and non phagocytic cells
Survival & Cause-Specific Mortality of Chilean Inflammatory Bowel Disease Patients
Thyroid hormone deficiency during pregnancy and its effects on the offspring immune response against an infection: Evaluation in a murine model of pneumococcal pneumonia
Transfer of an Unstable Pathogenicity Island of Salmonella Enteritidis Occurs by Conjugation and it is Increased by Temperature and pH. American Society for Microbiology User Generated
Transferencia horizontal de elementos genéticos inestables presentes en el cromosoma de Salmonella enterica

ConferenceProceedingWhole (10)

A veces se debe perder para ganar: Rol de la pérdida de regiones génicas en la patogenicidad de Salmonella
Desarrollo de Vacuna anti-VRS en Chile
Elementos genéticos inestables en Salmonella y su rol en virulencia.
Exploiting unstable genetic elements in Salmonella to promote protective immunity
Identificación de genes involucrados en la virulencia de Salmonella y su uso en el diseño de nuevas vacunas
Impact of virulence genes acquired by lateral gene transfer in the immune response against Salmonella
Molecular Mechanisms used by Salmonella to interfere with DC function
Role of anti-inflammatory cytokines in the susceptibility of the host to bacterial infections
Unstable Pathogenicity Islands in Salmonella and their role in virulence.
Vacunas Viejas, vacunas nuevas: mecanismos de acción

Letter (1)

Epidemic Clostridium difficile Ribotype 027 in Chile

Patent (9)

Composición farmacéutica para aminorar los síntomas y enfermedad de la infección respiratoria causada por el metapneumovirus humano (hmpv), que comprende al menos un agente que neutraliza la función de las moléculas tslp, y/o tslpr, y/o ox40l y/o cd177, y un excipiente farmacéuticamente aceptable, y su uso
Anticuerpos Monoclonales específicos para el antígeno pIII de Adenovirus Humano (ADV), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por ADV
Anticuerpos Monoclonales específicos para el antígeno P del Virus Respiratorio Sincicial humano (VRSh), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por VRSh
Anticuerpos monoclonales para el antígeno M2-1 del virus respiratorio sincicial (VRS), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por VRS
Formulación inmunogénica que confiere protección contra la infección o patología causada por el virus respiratorio sincicial (VRS) que comprende una cepa recombinante atenuada de Mycobacterium; y uso de la formulación inmunogénica para preparar una vacuna
Uso de la nucleoproteína recombinante del Virus Respiratorio Sincicial Humano para la supresión de células T y su aplicación en inmunoterapias contra enfermedades autoinmunes
Uso de los marcadores moleculares IL-3, IL-33, IL-12p40 para caracterizar la severidad de infecciones respiratorias por virus respiratorio sincicial y metapneumovirus humano
Anticuerpos Monoclonales específicos para el antígeno M del Virus Metapneumovirus humano (hMPV), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por hMPV
Uso de BCG recombinante que expresa la proteína P de hMPV como vacuna que genera inmunidad protectora contra la infección del virus respiratorio Metapneumovirus

Proyecto (46)

Fabricación industrial de dispositivo médico para infecciones respiratorias bajo norma 13.485
Caracterización de la respuesta clínica e inmunológica gatilladas por una vacuna recombinante contra VRS basada en BCG en voluntarios sanos
Understanding the consequences of gestational hypothyroxinemia over intestinal regulatory T cells and the predisposition of the offspring to develop inflammatory bowel disease
Understanding the contribution of neutrophil-derived interleukin 10 to the disease caused by Streptococcus pneumoniae
Caracterización de una vacuna contra el virus respiratorio sincicial
Gestational hypothyroxinemia increases the transmigration of immune cells into the central nervous system of the Offspring. Implications on autoimmune disease susceptibility
Elucidating the mechanisms of pathogenicity used by the human Respiratory Syncytial Virus to prevent T cell activation and cause Central Nervous System inflammation.
Evaluación preclínica de una vacuna intranasal contra Streptococcus pyogenes, el agente causante de faringoamigdalitis, fiebre reumática y fascitis necrotizante
Validación de un método de diagnóstico de infección respiratoria viral en secreciones nasofaríngea
Validación de un método de diagnóstico de infección respiratoria viral en secreciones nasofaríngea
Consorcio Tecnológico en Biomedicina Clínico-Molecular=> GENERACIÓN DE HERRAMIENTAS INMUNOLÓGICAS PARA DIAGNOSTICAR INFECCIONES RESPIRATORIAS Y ANTICIPAR SU SEVERIDAD
Herramientas inmunológicas para diagnostico infecciones respiratorias
Kit de diagnóstico rápido para la detección de virus herpes simplex 1 y varicela zoster
ROLE OF INTERLEUKIN 10 (IL-10) IN THE ABILITY OF BACTERIAL PATHOGENS TO CAUSE SYSTEMIC INFECTIONS IN THE HOST.
"STUDY OF THE MATERNAL HYPOTHYROXINEMIA EFFECT ON THE OFFSPRING T CELL RESPONSE AGAINST CENTRAL NERVOUS SYSTEM ANTIGENS DURING EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS"
Go To Market 2013 IVD Test for respiratory tract infections
Role of Heme oxygenase-1 in acute and chronic Intestinal Inflamation: Infectious and Immune models
ROLE OF HEME OXYGENASE-1 IN ACUTE AND CHRONIC INTESTINAL INFLAMATION=> INFECTIOUS AND IMMUNE MODELS.
Study of the maternal hypothyroxinemia effect on the offspring T cell response against central nervous system antigens during experimental autoimmune encephalomyelitis
STUDYING THE CONTRIBUTION OF HUMAN RESPIRATORY SYNCYTIAL VIRUS IN THE REDUCED T-CELL IMMUNITY TO MYCOBACTERIUM TUBERCULOSIS AND SUSCEPTIBILITY TO TUBERCULOSIS DEVELOPMENT
Caracterización de una Vacuna Recombinante contra el Virus Respiratorio Sincicial
Development of fast immunochromatographic kits for detection of respiratory viruses that are important for public health
Kit de detección de virus respiratorios que incorpora un redictor de respuesta inmune del paciente para establecer su gravedad
Desarrollo de vacunas
EVALUATION OF THE ROLE PLAYED BY THYROID HORMONES DURING GESTATION IN THE SEVERITY OF INFECTIONS CAUSED BY STREPTOCOCCUS PNEUMONIAE
Evaluation of the role played by thyroid hormones during gestation in the severity of infections caused by streptococcus pneumoniae
IDENTIFICATION OF THE MECHANISMS USED BY THE RESPIRATORY SYNCYTIAL VIRUS (RSV) TO INTERFERE WITH THE FUNCTION OF DENDRITIC CELLS AND IMPAIR T CELL IMMUNITY IN THE HOST
Kit de detección de virus respiratorios que incorpora un predictor de respuesta inmune del paciente para establecer su gravedad
EVALUATION OF SALMONELLA ENTERICA CAPACITY TO PROMOTE INFLAMMATORY BOWEL DISEASE IN SUSCEPTIBLE HOST
Evaluation of Salmonella enterica capacity to promote inflammatory bowel disease in susceptible host
Evaluation of the role played by thyroid hormones during gestation in the severity of infections caused by Streptococcus pneumonia
Desarrollo de vacunas
Desarrollo de kits inmunocromatográficos rápidos para la detección de virus respiratorios de importancia en salud pública
Desarrollo de vacunas contra virus respiratorios
EVALUACION DE LA PLASTICIDAD GENETICA DE ENTEROBACTERIAS PATOGENAS DURANTE EL CICLO INFECTIVO Y SU IMPACTO EN VIRULENCIA.
Evaluacion de la plasticidad genetica de enterobacterias patogenas durante el ciclo infectivo y su impacto en virulencia.
Expresión diferencial de genes presentes en profagos de enterobacterias: implicancias en patogénesis
Expresión diferencial de genes presentes en profagos de enterobacterias=> implicancias en patogénesis
Young researcher
Development of a Recombinant Vaccine against the Respiratory Syncytial Virus
Generación de una vacuna recombinante contra el virus respiratorio sincicial
Identificacion de los mecanismos moleculares utilizados por Salmonella enterica serovar Typhimurium para interferir con la funcion de la celula dendritica y evadir la respuesta inmune adquirida.
IDENTIFICACION DE LOS MECANISMOS MOLECULARES UTILIZADOS POR SALMONELLA ENTERICA SEROVAR TYPHIMURIUM PARA INTERFERIR CON LA FUNCION DE LA CELULA DENDRITICA Y EVADIR LA RESPUESTA INMUNE ADQUIRIDA.
Identificación de los mecanismos moleculares utilizados por Salmonella enterica serovar Typhimurium para interferir con la función de la célula dendrítica y evadir la respuesta inmune adquirida
Identification of the molecular mechanisms used by the enteropathogen Salmonella enterica serovar Enteritidis to avoid the host adaptive immune response
IFS Grant B/3764-1

Review (33)

Horizontally Acquired Homologs of Xenogeneic Silencers: Modulators of Gene Expression Encoded by Plasmids, Phages and Genomic Islands
BCG-Induced Cross-Protection and Development of Trained Immunity: Implication for Vaccine Design
Contribution of IDO to human respiratory syncytial virus infection
Contribution of Resident Memory CD8(+) T Cells to Protective Immunity against Respiratory Syncytial Virus and Their Impact on Vaccine Design
Herpes Simplex Virus Evasion of Early Host Antiviral Responses
Herpes Simplex Virus Type 1 Infection of the Central Nervous System: Insights Into Proposed Interrelationships With Neurodegenerative Disorders
Immune-Modulation by the Human Respiratory Syncytial Virus: Focus on Dendritic Cells
Expanding the Current Knowledge About the Role of Interleukin-10 to Major Concerning Bacteria
Heme Oxygenase-1 as a Modulator of Intestinal Inflammation Development and Progression
Human metapneumovirus: Mechanisms and molecular targets used by the virus to avoid the immune system
Intestinal Microbiota Influences Non-intestinal Related Autoimmune Diseases
Contribution of autophagy to antiviral immunity
Contribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosus
Evasion of Early Antiviral Responses by Herpes Simplex Viruses
Inflammatory damage on respiratory and nervous systems due to hRSV infection
Novel therapies and vaccines against the human respiratory syncytial virus
Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases
Central nervous system alterations caused by infection with the human respiratory syncytial virus
Respiratory Syncytial Virus: Pathology, therapeutic drugs and prophylaxis
Targeting Dendritic Cell Function during Systemic Autoimmunity to Restore Tolerance
Advances in understanding respiratory syncytial virus infection in airway epithelial cells and consequential effects on the immune response
Gene Elements that Regulate Streptococcus pneumoniae Virulence and Immunity Evasion
Modulation of Tumor Immunity by Soluble and Membrane-Bound Molecules at the Immunological Synapse
Mechanisms used by virulent Salmonella to impair dendritic cell function and evade adaptive immunity
Respiratory syncytial virus infection and immunity
Evasion of Host Immunity by Virulent Salmonella: Implications for Vaccine Design
Local cytokine response upon respiratory syncytial virus infection
Virulence Mechanisms Displayed by Salmonella to Impair Dendritic Cell Function
Impairment of T Cell Immunity by the Respiratory Syncytial Virus: Targeting Virulence Mechanisms for Therapy and Prophylaxis
Use of Genetically Modified Bacteria to Modulate Adaptive Immunity
T cell immunity evasion by virulent Salmonella enterica
Molecular interactions between dendritic cells and Salmonella: Escape from adaptive immunity and implications on pathogenesis
Molecular mechanisms used by Salmonella to interfere with dendritic cell function
240
Susan Bueno

Profesor Asociado

Genética Molecular y Microbiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

43
Claudia Riedel

Full Professor

Life Sciences

Universidad Andres Bello

Santiago, Chile

36
Alexis Kalergis

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

32
Pablo González

Associate Professor

Molecular Genetics and MIcrobiology

Pontificia Universidad Católica de Chile

Santiago, Chile

14
FELIPE MELO

Profesor Asistente

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

13
Omar Vallejos

Lab Manager y Coordinador

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

12
Maria Opazo

Profesor Asociado

Universidad de Las Américas

Santiago, Chile

12
Leandro Carreño

Profesor Asistente

Instituto de Ciencias Biomédicas

Universidad de Chile

Santiago, Chile

10
Karen Bohmwald

Investigador Postdoctoral

Pontificia Universidad Católica de Chile

Santiago, Chile

10
Nicolás Gálvez

Asistente de Investigación

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

9
Jorge Soto

Profesor Asistente

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

8
Manuel Alvarez

Gastroenterologist and Chief of Institute of Medicine

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

8
Hernán Peñaloza

Postdoctoral associate

Department of Medicine

University of Pittsburgh

Pittsburgh, Estados Unidos

8
Luis Piña

Investigador Postdoctoral

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

7
Hugo Tobar

Associate Reserch

Department of Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

6
Aniela Wozniak

Coordinador de Investigación

Dept Laboratorios Clínicos

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

6
Fernando Valiente

Profesor Asociado

ICBM

Universidad de Chile

Santiago, Chile

5
Eduardo Leiva

Profesor Asistente

Departamento de Ingeniería Hidráulica y Ambiental/ Departamento de Química Inorgánica

Pontificia Universidad Católica de Chile, Facultad de Química, Escuela de Ingeniería

Santiago, Chile

5
Yaneisi Vazquez

Directora técnica de proyectos

Genética Molecular

Pontificia Universidad Católica de Chile

Santiago, Chile

5
ANGELLO RETAMAL

Profesor Asistente

Biotecnología

Universidad de Antofagasta

Antofagasta, Chile

4
carolina iturriaga

Sub Directora Laboratorio de inmunología y Alergia Traslacional UC

Pediatria

Pontificia Universidad Católica de Chile

santiago, Chile

4
Carolina Llanos

Associate Professor

Pontificia Universidad Católica de Chile

Santiago, Chile

4
Catalina Pardo

Profesor Asistente

Dpto. de Salud del Niño y Adolescente

Pontificia Universidad Católica de Chile

Region Metropolitana, Chile

4
Francisco Salazar

Profesional Asistente

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

3
Juan Fuentes

Académico

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

3
Loni Berkowitz

Investigador postdoctoral

Nutrición, diabetes y metabolismo

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

3
Luis Venegas

Bioquímico/investigador

Anatomía Patológica

Clínica Alemana de Santiago

Santiago, Chile

3
Gisela Canedo

Investigadora y Profesora

Facultad de Odontología

Universidad de Los Andes

Santiago, Chile

3
Felipe Simon

Profesor Titular

Department of Biological Sciences

UNIVERSIDAD ANDRES BELLO FAC DE CS BIOLOGICAS, DPTO DE CS BIOLOGICAS

Santiago, Chile

3
Patricia García

Jefe de Laboratorio de Microbiologia

Escuela de Medicina

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE, LABORATORIO DE MICROBIOLOGÍA

Santiago, Chile

3
Patricio Ibañez

Asistant professor

Gastroenterology

PONTIFICIA UNIVERSIDAD CATOLICA

Santiago, Chile

3
Guido Mora

Académico/Investigador

Facultad Ciencias de la Salud

Universidad SEK

Santiago, Chile

3
Sandra Solari

Profesor Clinico Asociado

Laboratorios Clinicos

Facultad de Medicina - PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

3
Camila Covián

Investigador

Genética molecular y microbiología

Pontificia Universidad Católica

Santiago, Chile

2
Alvaro Elorza

FULL PROFESSOR

INSTITUTE OF BIOMEDICAL SCIENCES

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

2
David Naranjo

Profesor titular

Neurociencia

Universidad de Valparaíso

VALPARAISO, Chile

2
Christian Muñoz

Profesor Asociado

Tecnología Médica

Universidad de Antofagasta

Antofagasta, Chile

2
Francisco Ibañez

Phd(c)

Genética Molecular y Microbiología

Pontificia Universidad Catolica de Chile

Santiago, Chile

2
Carolina Prado

Investigador Joven

Fundacion Ciencia y Vida

Santiago, Chile

2
DIANA ALVAREZ

Egresado Doctorado Ciencias Biológicas

Pontificia Universidad Católica de Chile

Santiago de Chile, Chile

2
Fabián Vega

Investigador postdoctoral

Oftalmología

Universidad de Chile

Santiago, Chile

2
Gaspar Pacheco

Estudiante de pregrado

Departamento de Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

2
ANDRES JORQUERA

GASTROENTEROLOGO

CONSULTORIO EXTERNO

HOSPITAL DE CURANILHUE

CURANILAHUE, Chile

2
Carolina Quezada

Postdoctoral researcher

CIBQA

Universidad Bernardo O'Higgins

Santiago, Chile

2
LILIANA GONZÁLEZ

Investigador

Departamento de Laboratorios Clínicos

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Abel Vasquez

Jefatura de Sección

Salud Ambiental

Instituto de Salud Publica de Chile

Santiago, Chile

2
Christian Palavecino

Profesor asistente

Universidad Central de Chile

Santiago, Chile

2
Daniela Araya

Investigador

Escuela Ingenieria Bioquimica

PUCV

Valparaiso, Chile

1
Raquel Quatrini

Research Associate

Fundación Ciencia & Vida

Santiago, Chile

1
Hernan Gonzalez Diaz

Associate Professor

Cirugía Oncológica

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Paula Muñoz

Clinical Research Center Director

Universidad del Desarrollo

Santiago, Chile

1
Claudia Saavedra

Full Professor

Departmento de Ciencias de la Vida

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

1
Paulette Legarraga

Sub jefe técnico Laboratorio

Laboratorios Clínicos

Clínica Alemana de Santiago

Santiago, Chile

1
Ricardo Soto

PROFESOR ASOCIADO

FACULTAD DE MEDICINA

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Carlos Fardella

Profesor Titular

Endocrinología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
María Domínguez

Profesora asistente adjunta

Departamento de Salud Pública

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Farides Saavedra

Investigadora

Fundación Ciencia y Vida

Ñuñoa, Chile

1
David Holmes

Head, Laboratory of Bioinformatics and Genome Biology

Center for Bioinformatics and Genome Biology

FUNDACION CIENCIA & VIDA

Santiago, Chile

1
Monique Le Corre

Assistant Professor

Faculty of medicine, Pediatric division

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Rodrigo Sandoval

Director de departamento

Ciencias Biomédicas

UNIVERSIDAD CATOLICA DEL NORTE

Coquimbo, Chile

1
Esteban Aliaga

Profesor

Kinesiología

Universidad Católica el Maule

Talca, Chile

1
Alan Briones

Bioquímico Clínico

Hospital San Juan de Dios

Santiago, Chile

1
Marjorie Pizarro

Asistente de Investigacion

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

1
Alejandro Arriagada

Coordinador y docente

Núcleo de Ciencias Biológicas

Universidad Mayor de Chile

Santiago, Chile

1
Marlén Barreto

Profesor asociado

UNIVERSIDAD AUTONOMA DE CHILE

Santiago de Chile, Chile

1
Marysol Paz

PhD student

Universidad Técnica Federico Santa María

Valparaíso, Chile

1
Evelyn Jara

Docente/Investigador

Ciencias Básicas

Universidad Santo Tomás

Temuco, Chile

1
Oslando Padilla

Estadístico

Salud Pública

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Gabriel Krüger

Investigador Doctoral

Universidad Andrés Bello

Santiago Centro, Chile

1
Aaron Cortes

Jefe de Investigación

Dirección Médica

Clínica Universidad de los Andes

Santiago, Chile

1
Andrea Leiva

Coordinadora plataforma de secuenciación

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Maria Hernandez

Investigador Post Doctoral

Universidad de Chile

Santiago, Chile

1
Luis Michea

PROFESOR ASOCIADO

PROGRAMA FISIOLOGIA Y BIOFISICA

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Andres Herrada

Principal Investigator

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Talca, Chile

1
Alvaro Becerra

Profesor Asociado

Ciencias Químico y Biológicas

Universidad Bernardo O'Higgins

Santiago, Chile

1
Marcela Ferres

Head of Department

Pediatric Infectious Diseases and Immunology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Emma Rey

Professor/Researcher

Instituto de Ciencias e Innovación en Medicina (ICIM)

Universidad del Desarrollo

Santiago, Chile

1
Felipe Court

Full Professor and Director

Center for Integrative Biology

Universidad Mayor

Huechuraba, Chile

1
Josefina Duran

Associate Professor

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
JOSE MIRANDA

Estudiante de Doctorado

Nutrición, Diabetes y Metabolismo

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Pablo Castro

JEFE DIVISION

DIVISION ENFERMEDADES CARDIOVASCULARES

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

1
Denis Saure

Assistant Professor

Ingeniería Industrial

Universidad de Chile

Santiago, Chile

1
Daniel Paredes

Associate Professor

Department of Biological Sciences

Universidad Andrés Bello

Santiago, Chile

1
Orlando Diaz

Profesor Asociado

Enfermedades Respiratorias

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Eduardo Catalán

Lab Manager

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

1
YORLEY DUARTE

profesor Asistente

Universidad Andrés Bello

Santiago, Chile

1
Paulina Dreyse

Profesor Asistente

Departamento de Química

Universidad de Chile

Santiago, Chile

1
Annette Trombert

Directora de Escuela

Biotecnología

UNIVERSIDAD MAYOR, INSTITUTO DE BIOTECNOLOGÍA, CENTRO DE GENÓMICA Y BIOINFORMÁTICA

Santiago, Chile

1
Aldo Barrera

Postdoctor

Enfermedades Infecciosas e Inmunología pediátrica

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Mirentxu Iruretagoyena

Jefe Seccion Inmunologia

Laboratorio Clinico

Clinica Alemana de Santiago

Santiago, Chile

1
Floria Pancetti

Director de Departamento

Ciencias Biomédicas

UNIVERSIDAD CATOLICA DEL NORTE

Coquimbo, Chile

1
Jorge Valdes

I

CENTRO DE GENOMICA Y BIOINFORMATICA

UNIVERSIDAD MAYOR

Santiago, Chile

1
Sebastián Gatica

Investigador Postdoctoral

Instituto Milenio de Inmunología e Inmunoterapia

Santiago, Chile