Demergasso_picture.png_thumb90

Cecilia Susana Demergasso Semenzato

Directora

UNIVERSIDAD CATÓLICA DEL NORTE

Antofagasta, Chile

Líneas de Investigación


Geomicrobiology in desert-saline environments; Astrobiology; Biomining

Educación

  •  Microbiology, Universidad de Buenos Aires. Argentina, 2004
  •  Teology, Pontificia Universidad Católica Argentina. Argentina, 1986
  •  en Análisis Clínicos y Bioquímica, Universidad de Buenos Aires. Chile, 1976

Experiencia Académica

  •   Directora Full Time

    UNIVERSIDAD CATOLICA DEL NORTE

    Antofagasta, Chile

    Enero 2002 - A la fecha

  •   Investigadora Other

    UNIVERSIDAD CATOLICA DEL NORTE

    Ciencias

    Antofagsta, Chile

    Enero 1997 - Enero 2002

  •   Associated researcher Part Time

    Scientific and Technology Center for Mining

    Antofagasta, Chile

    Enero 2006 - Enero 2015

Experiencia Profesional

  •   Bioquímica Full Time

    Hospital Municipal de San Miguel, Provincia de Buenos Aires

    San Miguel, Argentina

    Enero 1977 - Enero 1978

  •   Académica Part Time

    Universidad Católica del Norte

    Antofagasta, Chile

    Enero 1986 - Enero 1994

  •   Asistente Equipo Vicerrectoría Académica Full Time

    Universidad Católica del Norte

    Antofagasta, Chile

    Enero 1994 - Enero 1997

Formación de Capital Humano


Tesis de pregrado: 24
Tesis de posgrado: 12
Supervisión de posdoctorandos: 8


Difusión y Transferencia


Patentes:
• Patente Nº 46.790, otorgada por el Instituto Nacional de Propiedad Industrial (INAPI), con fecha de concesión 14 de Enero de 2011. Título: “Método para extraer ADN obtenidos de procesos industriales productivos de cobre que usen biolixiviación y contengan baja concentración celular para su uso posterior en aplicaciones de biología molecular”. Autores: Cecilia Demergasso, Lorena Escudero González, Pedro Galleguillos Pérez, Víctor Zepeda Alvarez, Alex Echeverría V.
• Solicitud de Patente Nº 864-2009. Título: “Método para extraer ARN de microorganismos desde muestras líquidas o sólidas, obtenidas de procesos industriales y experimentales de biolixiviación, para su uso en aplicaciones de biología molecular”. Autores: Cecilia Demergasso, Lorena Escudero González, Pedro Galleguillos Pérez, Víctor Zepeda Alvarez, Alex Echeverría Vega.
• US Patente N° 7.422.687 con fecha de concesión 9 de Septiembre de 2008. Título: “Proceso biotecnológico para el tratamiento de lodos hidróxidos con contenido de Arsénico provenientes de procesos de potabilización de agua, que utilizan FeCl3 como coagulante, mediante la acción de bacterias reductoras de sulfato”. Autores: Cecilia Demergasso, Lorena Escudero González, Pedro Galleguillos Pérez, Víctor Zepeda Alvarez.
• Patente Nº267115, otorgada por el Instituto Mexicano de la Propiedad Industrial, con fecha de concesión 29 de Mayo de 2009. Título: "Proceso biotecnológico para el tratamiento de lodos hidróxidos con contenido de As provenientes de procesos de potabilización de agua, que utilizan FeCl3 como coagulante, mediante la acción de bacterias reductoras de sulfato”.
• Patente Nº47165, otorgada por el Instituto Nacional de Propiedad Industrial (INAPI), con fecha de concesión 21 de Febrero de 2011. Título: "Proceso biotecnológico para el tratamiento de lodos hidróxidos con contenido de As provenientes de procesos de potabilización de agua, que utilizan FeCl3 como coagulante, mediante la acción de bacterias reductoras de sulfato”. Autores: Cecilia Demergasso, Lorena Escudero González, Pedro Galleguillos Pérez, Víctor Zepeda Alvarez.
• Patente N°: AR061659B1, otorgada por el Instituto Nacional de la Propiedad Industrial de la República Argentina, con fecha 23 de Agosto de 2013. Título: "Proceso biotecnológico para el tratamiento de lodos hidróxidos con contenido de As provenientes de procesos de potabilización de agua, que utilizan FeCl3 como coagulante, mediante la acción de bacterias reductoras de sulfato”. Autor(es): "Cecilia Demergasso, Lorena Escudero González, Pedro Galleguillos Pérez, Víctor Zepeda Alvarez.
• Solicitud de Patente N° 1474-09. Título: “A method of treating a sulphide mineral”. Autores: RAUTENBACH, George Frederick, DAVIS-BELMAR, Carol Susan, DEMERGASSO, Cecilia Susana.
• Solicitud de Patente Nº 2007202864 y 897/KOL/2007 en Australia e India, respectivamente. Título: "Proceso biotecnológico para el tratamiento de lodos hidróxidos con contenido de As provenientes de procesos de potabilización de agua, que utilizan FeCl3 como coagulante, mediante la acción de bacterias reductoras de sulfato”. Autor(es): "Cecilia Demergasso, Lorena Escudero González, Pedro Galleguillos Pérez, Víctor Zepeda Alvarez.
• Solicitud de Patente: N° 02111-2012. Título: ““Procedimiento para la determinación de la presencia/ausencia y actividad metabólica de microorganismos acidófilos medidas en función de la expresión transcripcional de su complemento génico global y que comprende un método para la obtención de RNA en la cantidad y calidad necesarias y el análisis con un microarreglo multigenómico propósito específico”. Autores: Cecilia Demergasso (UCN), Amir Shmaryahu (FCV), Raquel Quatrini (FCV), Pedro Galleguillos (CICITEM), Mauricio Acosta Grinok, David S. Holmes (FCV). Agosto 2014.

Liderazgo de proyectos de investigación industrial financiados por empresas del sector minero y de recursos hídricos, entre otros.

Presidenta del Comité Organizador del Congreso Chileno de Microbiología año 2010, en Antofagasta.
Presidenta del Comité Organizador del International Biohydrometallurgy Symposium, Antofagasta 2013.



 

Article (42)

Microbiology and Nitrogen Cycle in the Benthic Sediments of a Glacial Oligotrophic Deep Andean Lake as Analog of Ancient Martian Lake-Beds
Subsurface Microbial Habitats in an Extreme Desert Mars-Analog Environment
A thiotrophic microbial community in an acidic brine lake in Northern Chile
Biomarkers and Metabolic Patterns in the Sediments of Evolving Glacial Lakes as a Proxy for Planetary Lake Exploration
Decision support system for bioleaching processes
Identification of trehalose as a compatible solute in different species of acidophilic bacteria
Watershed-Induced Limnological and Microbial Status in Two Oligotrophic Andean Lakes Exposed to the Same Climatic Scenario
Is the growth of microorganisms limited by carbon availability during chalcopyrite bioleaching?
Microbial Community Structure and the Persistence of Cyanobacterial Populations in Salt Crusts of the Hyperarid Atacama Desert from Genome-Resolved Metagenomics
Draft genome sequence of chloride-tolerant Leptospirillum ferriphilum Sp-Cl from industrial bioleaching operations in northern Chile
One-Dimensional TiO 2 -B Crystals Synthesised by Hydrothermal Process and Their Antibacterial Behaviour on Escherichia coli
Rates and geochemical processes of soil and salt crust formation in Salars of the Atacama Desert, Chile
The Ecological Coherence of Temperature and Salinity Tolerance Interaction and Pigmentation in a Non-marine Vibrio Isolated from Salar de Atacama
Copper resistance, motility and the mineral dissolution behavior were assessed as novel factors involved in bacterial adhesion in bioleaching
Bioleaching of copper secondary sulfide ore in the presence of chloride by means of inoculation with chloride-tolerant microbial culture
Draft Genome Sequence of Nitrincola sp. Strain A-D6, an Arsenic-Resistant Gammaproteobacterium Isolated from a Salt Flat
Variation in microbial community from predominantly mesophilic to thermotolerant and moderately thermophilic species in an industrial copper heap bioleaching operation
A Descriptive Model for Microbial Population Dynamics in a Copper Sulphide Bioleaching Heap with Spatial and Physicochemical Considerations
AHL signaling molecules with a large acyl chain enhance biofilm formation on sulfur and metal sulfides by the bioleaching bacterium Acidithiobacillus ferrooxidans
Distribution of Microbial Arsenic Reduction, Oxidation and Extrusion Genes along a Wide Range of Environmental Arsenic Concentrations
Molecular preservation in halite- and perchlorate-rich hypersaline subsurface deposits in the Salar Grande basin (Atacama Desert, Chile): Implications for the search for molecular biomarkers on Mars
Parameters, influencing the microbial oxidation activity in the industrial bioleaching heap at Escondida mine, Chile
Variance Calculations for Quantitative Real-Time PCR Experiments with Multiple Levels of Replication
Effect of organic extractant LIX 84IC, pH and temperature changes on bioleaching microorganisms during SX treatment
Enrichment of arsenic transforming and resistant heterotrophic bacteria from sediments of two salt lakes in Northern Chile
A Microbial Oasis in the Hypersaline Atacama Subsurface Discovered by a Life Detector Chip: Implications for the Search for Life on Mars
Archaeal diversity along a subterranean salt core from the Salar Grande (Chile)
Correction to “The High-Lakes Project”
Microbial succession during a heap bioleaching cycle of low grade copper sulfides Does this knowledge mean a real input for industrial process design and control?
Prokaryotic diversity pattern in high-altitude ecosystems of the Chilean Altiplano
Diversity of Bacteroidetes in high-altitude saline evaporitic basins in northern Chile
Dynamic of active microorganisms inhabiting a bioleaching industrial heap of low-grade copper sulfide ore monitored by real-time PCR and oligonucleotide prokaryotic acidophile microarray
The High-Lakes Project
Identification of differentially expressed genes in an industrial bioleaching heap processing low-grade copper sulphide ore elucidated by RNA arbitrarily primed polymerase chain reaction
Novelty and spatio-temporal heterogeneity in the bacterial diversity of hypersaline Lake Tebenquiche (Salar de Atacama)
Life in the Atacama: Searching for life with rovers (science overview)
Microbial precipitation of arsenic sulfides in Andean salt flats
Molecular characterization of microbial populations in a low-grade copper ore bioleaching test heap
Distribution of prokaryotic genetic diversity in athalassohaline lakes of the Atacama Desert, Northern Chile
Microbial mats from the Llamara salt flat, northern Chile
Assessment of bioavailable arsenic and copper in soils and sediments from the Antofagasta region of northern Chile
The borate deposits in Chile.

ConferencePaper (24)

From knowledge to best practices in bioleaching
Microbial survey on industrial bioleaching heap by high-throughput 16s sequencing and metagenomics analysis
Transcription dynamics of CBB-pathway genes in acidithiobacillus thiooxidans growing under different CO2 levels
Global genomic expression of active bacteria populations that transform arsenic in sediments of Salar de Ascotán, Chile
Analysis of gene expression as marker of relevant metabolisms, in three Acidithiobacillus ferrooxidans strains, in different growth conditions
Analysis of gene expression in response to copper stress in Acidithiobacillus ferrooxidans strain D2, isolated from a copper bioleaching operation
Bioleaching of covellite from low grade copper sulphide ore and tails
Biologically assisted copper secondary sulfide ore leaching in the presence of chloride
Effect of contact with organic extractant LIX 84IC during solvent extraction process on the re-establishment of growth of bioleaching microorganisms
Effect of increased acid concentration on the microbial population inhabiting an industrial heap bioleaching plant
Estimation of ionic load effect on the oxidizing activity of the microbial population in the heap bioleaching process at Escondida Mine
From mesophilic to moderate thermophilic populations in an industrial heap bioleaching process
GEOCHEMISTRY AND MICROBIOLOGY IN AN ACIDIC, HIGH ALTITUDE (4,000 m) SALT FLAT. HIGH ANDES, NORTHERN CHILE
Proteo and Actinobacteria diversity at a sulfide, salt and acid -rich lake in the north of Chile
Temporal dynamics of genes involved in metabolic pathways of C and N of L. ferriphilum, in the industrial bioleaching process of Escondida mine, Chile
Assessment of microbial adhesion in mixed cultures to sulfide minerals using CARD-FISH techniques
Characterization of oxidizing activity of a microbial community in an industrial bioleaching heap
Comparison between the bacterial populations from solutions and minerals in 1 m test columns and the industrial low grade copper sulphide bioleaching process in the Escondida Mine, Chile
Differential gene expression of industrial bioleaching transcriptomes by Leptospirillum ferrooxidans DNA Microarray
Microbial succession during a heap bioleaching cycle of low grade copper sulphides. Does this knowledge mean a real input for industrial process design and control?
Normalization of quantitative real-time PCR data of identified genes from an industrial bioleaching operation
Bacterial activity at low temperature in cultures derived from a low-grade copper sulphide bioleaching heap at the Escondida Mine, Chile
Differential genetic expression in heap bioleaching of low-grade copper sulphide ore at Escondida Mine, Chile
Monitoring the microbial community inhabiting a low-grade copper sulphide ore by quantitative real-time PCR analysis of 16S rRNA genes

Article (21)

Draft genome sequence of the acidophilic, Gram positive, moderate thermophile Sulfobacillus thermosulfidooxidans CBAR13 isolated from the bioleaching heap at Escondida copper mine, Chile
The Ecological Coherence of temperature and salinity tolerance interaction and pigmentation in a non-marine Vibrio isolated from Salar de Atacama
Blue-copper proteins: Expression of coding genes from Sulfobacillus spp. and iron oxidation in column bioleaching tests.
Copper resistance, motility and the mineral dissolution behavior were assessed as novel factors involved in bacterial adhesion in bioleaching
Insights into the active carbon fixation pathways of a microbial community in a chalcopyrite bioleaching column.
Variation in microbial community from predominately mesophilic to thermotolerant and moderately thermophilic in an industrial copper heap bioleaching operation.
Analysis of gene expression as marker of relevant metabolisms, in three Acidithiobacillus ferrooxidans strains, in different growth conditions
Analysis of gene expression in response to copper stress in Acidithiobacillus ferrooxidans strain D2, isolated from a copper bioleaching operation
Distribution of Microbial Arsenic Reduction, Oxidation and Extrusion Genes along a Wide Range of Environmental Arsenic Concentrations
Effect of organic extractant LIX 84IC, pH and temperature changes on bioleaching microorganisms during SX treatment.
Parameters, influencing the microbial oxidation activity in the industrial bioleaching heap at Escondida mine, Chile
Temporal dynamics of genes involved in metabolic pathways of C and N of L. ferriphilum, in the industrial bioleaching process of Escondida mine, Chile
AHL signaling molecules with a large acyl chain enhance biofilm formation on sulfur and metal sulfides by the bioleaching bacterium Acidithiobacillus ferrooxidans.
Enrichment of arsenic transforming and resistant heterotrophic bacteria from sediments of two salt lakes in Northern Chile
Archaeal diversity along a subterranean salt core from the Salar Grande (Chile)
Microbial succession during a heap bioleaching cycle of low grade copper sulphides. Does this knowledge mean a real input for industrial process design and control?
Identification of differentially expressed genes in an industrial bioleaching heap processing low-grade copper sulphide ore elucidated by RNA arbitrarily primed polymerase chain reaction
Novelty and spatio–temporal heterogeneity in the bacterial diversity of hypersaline Lake Tebenquiche (Salar de Atacama).
From knowledge to best practices in bioleaching
Is the growth of microorganisms limited by carbon availability during chalcopyrite bioleaching?
Transcription dynamics of CBB-pathway genes in Acidithiobacillus thiooxidans growing under different CO2 levels

Proyecto (20)

Development of a biotechnological product to repair cracks in concrete
Biotechnological process for removing sulfate from industrial solutions of hydrometallurgical operations
Technology of industrial information, based on knowledge management, for making decision support in bioleaching processes.
Changing Planetary Environment and the Fingerprints of Life
Changing Planetary Environment and the Fingerprints of Life”.
An expert system for industrial bioleaching processes
Planetary Lake Lander
Robotic Investigation of Subsurface Life in the Atacama Desert
Microbial transformations of arsenic in saline environments in Northern Chile
Virus population dynamics and acquired virus resistance in bioleaching microbial communities
Development of DNA microarrays for transcriptomic monitoring in industrial processes of copper bioleaching”.
R&D for a genetic expression control system to optimize industrial copper bioleaching
The wetlands of the Andean Puna: reservoir of microorganisms that participate in the arsenic cycle. Its biotechnological potential against pollution
Palaeographic meaning and palaeoclimatic evolution of the continental sedimentary basins of northern Chile. An geologic/geomicrobial approach to the understanding of the basins of arid environments
Limits of Life in the Atacama. Long-Duration Robotic Investigation of Habitats and Evidence of Life in the Atacama Desert of Chile.
Microbiology related to biotechnological processes in productive sectors in Northern Chile and neighbour countries
Comparison of diversity of the microbial communities inhabiting Salt flats located in different geological frames in north of Chile by DGGE technique
Bioprecipitation of arsenic in waste water from mining and water companies
Improving the R&D capacities of the Universidad Católica del Norte through the acquisition of an X-ray Diffractometer and Ion chromatographer
INCORPORATION OF NEW ANALYTICAL CAPABILITIES FOR THE INVESTIGATION OF REGIONAL PROBLEMS

ConferenceProceedingWhole (1)

Integration of Science and Industrial Knoweledge on Biohydrometallurgy

BookWhole (1)

Dynamics of declining lake habitat in changing climate

BookSection (1)

Scientific Monitoring of Industrial Bioleaching Process.
89
Cecilia Demergasso

Directora

Vicerrectoría de Investigación y Desarrollo Tecnológico

UNIVERSIDAD CATÓLICA DEL NORTE

Antofagasta, Chile

15
Guillermo Chong

Professor, researcher

Geological sciences

UNIVERSIDAD CATÓLICA DEL NORTE DPTO. CS. GEOLÓGICAS

Antofagasta, Chile

11
Lorena Escudero

Investigador

Biotecnología Industrial

CICITEM

Antofagasta, Chile

9
Mauricio Acosta

Investigador

Universidad Católica del Norte

Antofagasta, Chile

9
Alex Echeverria

Researcher

Vicerrectoría de investigación y postgrado

Universidad Católica del Maule

Talca, Chile

9
Pedro Galleguillos

Investigador

Centro de Investigación Científico y Tecnológico para la Minería

Antofagasta, Chile

9
Pedro Galleguillos

Investigador

Biotecnología Industrial

Centro de Investigación Cientifico y Tecnologico para la Minería

Antofagasta, Chile

6
Felipe Galleguillos

Profesional

Centro de Biotecnología

Universidad de Concepción

Concepción, Chile

5
Francisco Remonsellez

Professor

Ingenieria Química

UNIVERSIDAD CATÓLICA DEL NORTE

Antofagasta, Chile

5
DINA CAUTIVO

Investigador

Centro de Biotecnologia

Universidad Católica del Norte

Antofagasta, Chile

4
Victor Zepeda

Investigador

Centro de Biotecnología

Antofagasta, Chile

3
Sabrina Marin

Investigadora

Centro de Biotecnología

Universidad Católica del Norte

Antofagasta, Chile

3
Nicolas Simon Dominique Guiliani

Profesor Titular

Biología

UNIVERSIDAD DE CHILE

Santiago, Chile

3
Cristina Dorador

PROFESSOR

Biotechnology

UNIVERSIDAD DE ANTOFAGASTA

ANTOFAGASTA, Chile

2
David Holmes

Director

Center for Bioinformatics and Genome Biology

FUNDACION CIENCIA PARA LA VIDA Y UNIVERSIDAD ANDRES BELLO (UNAB)

Santiago, Chile

2
Jenny Blamey

Director

Research and Development

FUNDACIÓN CIENTÍFICA Y CULTURAL BIOCIENCIA

Santiago, Chile

2
Daniela Meneses

Encargada de Laboratorio de Complejidad Microbiana y Ecología Funcional

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

1
Mario Vera

Profesor Asistente

Instituto de Ingeniería Biológica y Medica

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Raquel Quatrini

Research Associate

Fundación Ciencia & Vida

Santiago, Chile

1
Lina Ruiz

Academico Docente Investigador

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

1
Alex Gonzalez

Profesor Asociado

Ciencias Biologicas

Universidad de los Lagos

Osorno, Chile

1
MARCO PFEIFFER

FACULTY

INGENIERIA Y SUELOS

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Camila Salazar

Investigador

Biomédico

Universidad de Antofagasta

Antofagasta, Chile

1
Renato Chávez

Associate Professor

Biology

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Gloria Levicán

Académica Profesora Asociada

Departamento de Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Karem Gallardo

Investigador postdoctoral

Universidad Católica del Norte

Antofagasta, Chile