Man

Emma Marcela Hernández Ríos

Académico 44 h, profesor titular

Universidad de Chile, Facultad de Odontología

SANTIAGO, Chile

Líneas de Investigación


Etiology and pathogenesis of periodontitis from periodontal and endodontic origin, their systemic complications and identification of biomarkers in oral fluids

Educación

  •  dental sciencies, UNIVERSITY OF HELSINKI. Finlandia, 2012
  •  Dental Sciences Mention Oral Pathology, UNIVERSIDAD DE CHILE. Chile, 2006
  •  SPECIALIST IN ORAL PATHOLOGY AND MEDICINE, UNIVERSIDAD DE CHILE. Chile, 2012
  •   DENTIST, UNIVERSIDAD DE CHILE. Chile, 1998
  •  Dentistry, UNIVERSIDAD DE CHILE. Chile, 1998

Experiencia Académica

  •   Profesor titular Full Time

    UNIVERSIDAD DE CHILE

    ODONTOLOGIA

    SANTIAGO, Chile

    Enero 2001 - A la fecha

  •   Associate researcher Part Time

    Universidad Autónoma de Chile

    Cs. de la Salud

    Santiago, Chile

    Enero 2016 - Enero 2019

  •   Member of the study group medicine G2-G3 National fund of scientific and technological development Part Time

    FONDECYT

    Santiago, Chile

    Enero 2016 - A la fecha

  •   Director of the Doctorate Program of dental sciences Full Time

    UNIVERSIDAD DE CHILE

    Santiago, Chile

    Enero 2013 - Enero 2019

Experiencia Profesional

  •   Chief of Anatomic Pathology Service Full Time

    Universidad de Chile

    Santiago, Chile

    Enero 2017 - A la fecha

  •   Specialist in Oral Pathology and Medicine Part Time

    Hospital Clínico Universidad de Chile

    Santiago, Chile

    Enero 2019 - A la fecha

Formación de Capital Humano


Undergraduate thesis supervision
1. "Role of the O antigen of the lipopolysaccharide of Porphyromonas gingivalis in the profile of differentiation of macrophages". Student: Alfredo Ignacio Castro Martínez. 2019. Financing: FONDECYT 1160741.
2. Cardiovascular risk associated with systemic inflammation in patients with asymptomatic apical periodontitis. Student: Francisca Quinlan Binelli, year 2019. Financing: FONDECYT 1160741.
3. Levels of expression of toll-4 receptor (TLR-4), interleukin (IL) -10 and IL-12 in peripheral blood mononuclear cells of patients with asymptomatic apical periodontitis. Student: Lynn Barstow Melgarejo, year 2019. Financing: FONDECYT 1160741.
4. Role of the O antigen of the lipopolysaccharide of Porphyromonas gingivalis in the profile of differentiation of macrophages. Student: Alfredo Castro Martínez, year 2019. Financing: FONDECYT 1160741.
5. Immunolocalization of the signaling complex of interleukin-6 in periapical lesions of endodontic origin. Student: Catalina Schweitzer Gatica, year 2019. Financing: FONDECYT 1160741.
6. Prevalence of teeth treated endodontically in a Chilean subpopulation. Student: Macarena Becker Pinto, year 2018. Financing: FONDECYT 1160741. 2018.
7. "Humoral immune response and endotoxemia in endodontic infection with Porphyromonas endodontalis and Porphyromonas gingivalis in Asymptomatic Apical Periodontitis. "Dept. of Pathology and Oral Medicine. University of Chile. Student: student: Valeska Fariña Espinosa. Year 2015. Financing: FONDECYT 1120138.
8. "Morphological and Molecular Characterization of Mandibular Temporomal Ankylosis". Dept. of Pathology and Oral Medicine. University of Chile. Student: student Rubén Soto Galaz. Year 2015. Financing: FIOUCH13-004.
9. "Levels of Tartrate-Resistant Acid Phosphatase (TRAP), Ligand Activating Receptor for the Nuclear Factor NFkB (RANKL) and Osteoprotegerin (OPG) in Symptomatic and Asymptomatic Periapical Lesions of Endodontic Origin". Dept. of Pathology and Oral Medicine. University of Chile. Student: Macarena Salinas Muñoz. Year 2015. Financing: FONDECYT 1120138
10. Myeloperoxidase (MPO) levels in Periapical Lesions of Endodontic Origin. Dept. of Pathology and Oral Medicine. University of Chile. Student: Marcela Bolbarán Gómez. Main tutor Year 2014. FONDECYT financing 1120138.
11. C-Reactive Protein in Apical Lesions of Endodontic Origin. Department of Conservative Dentistry and Pathology and Oral Medicine. University of Chile. María José Bordagaray Principal Tutor. Year 2013. Financing FONDECYT 1120138.
12. "Association between Asymptomatic Apical Periodontitis and Modifiable Risk Factors of Cardiovascular Diseases" Germán Contreras Silva Associate Tutor. Financing FONDECYT 1120138. Year 2013.
13. "Levels of Myeloperoxidase (MPO) in Periapical Teeth Exudate with Asymptomatic Apical Periodontitis (PAA) Measured Pre and Post-Endodontic Medications with Calcium Hydroxide". Josefa Belén Castro Salas. Associate tutor. Year 2013. Financing FONDECYT 1120138.
14. Tissue Localization of Matrix Metalloproteinase -12 in Periapical Lesions Consecutive to Septic Pulp Necrosis and Healthy Periapical Tissue, Student: Pilar Jerez. School of Dentistry University of Chile. Associate tutor. Year 2012. Financing FONDECYT 1090461.
15. Levels of Myeloperoxidase (MPO) in Crevicular Gingival Fluid (FGC) of Teeth with Asymptomatic Apical Periodontitis (PAa). Student: Valentina Aranda González. Responsible tutor Year 2012. Financing FONDECYT 1090461.
16. Thesis Levels of Crosslinked Piridinoline of Type I Colloid Tipelactopeptide (ICTP) in Crevicular Gingival Fluid (FGC) of Teeth with Asymptomatic Apical Periodontitis (PAa). Student: Gianfranco Arce Salvi. Year 2012. Financing FONDECYT 1090461.
17. Levels of Vascular Endothelial Growth Factor (VEGF-A) in Periapical Lesions Consecutive Pulp Necrosis and Periodontal Ligament. Student: Magdalena Infante Figueroa. Year 2011. Financing FONDECYT 1090461.
18. Levels of Vascular Endothelial Growth Factor (VEGF) and Interleukin-1B in Gingival Crevicular Fluid (FCG) of Teeth with Asymptomatic Apical Periodontitis (PAa) Pre and Post Endodontic Treatment (2011). Student: Gustavo Pérez Serrano. Year 2011. Financing FONDECYT 1090461.
19. Levels of ICTP in Asymptomatic Apical Periodontitis and its Association with Periradicular Tissues. Student: Pamela Giralt Year 2011. Financing FONDECYT 1090461.
20. Levels of Cathepsin K in Crevicular Teeth Gingival Fluid with Asymptomatic Apical Periodontitis. Student: Loreto Espinoza. Year 2010. Financing FONDECYT 1090461.
21. Expression of Extracellular Matrix Metalloproteinase-13 (MMP-13) in Teeth with Asymptomatic Apical Periodontitis. Student: Andrea González. Year 2010. Financing FONDECYT 1090461.

Postgraduate Thesis (Master and Doctorate):
1. Polarization of macrophages in clinically symptomatic forms of apical periodontitis: Role of Lipopolysaccharide of Porphyromonas species on the expression of Toll-like receptors and their epigenetic regulation. Doctorate Program in Dental Sciences, University of Chile. Responsible tutor Student: Pablo Veloso Matta, year 2018. Financing FONDECYT 1160741. Status: Qualification exam approved.
2. Systemic inflammation and endodontic infection by Porphyromonas endodontalis in patients with asymptomatic apical periodontitis. Master's Program in Dental Sciences mention Periodontology, University of Chile. Responsible tutor Student: Patricia Huamán Chipana, year 2017. Financing FONDECYT 1120138.
3. Effects of the stimulation of human periodontal ligament fibroblasts with IL-6 on the synthesis of C-reactive protein (CRP) and proinflammatory cytokines. Master's Program in Dental Sciences mention Periodontology, University of Chile. Responsible tutor Student: Arnoldo Hernández Caldera, 2015. Funding FONDECYT 1120138.
4. Effect of stimulation with the different serotypes of Porphyromonas gingivalis and Aggregatibacter actinomycetencomitans on the activity of TCD4 + lymphocytes and bone resorption in vitro. Master's Program in Dental Sciences mention Periodontology, University of Chile. Associate tutor. Student: Student Melgar Samanta Rodríguez. Year 2014. FONDECYT 11100298.
5. Markers of bone metabolism in gingival crevicular fluid as a potential diagnostic tool for chronic inflammatory diseases of the marginal and apical periodontium. Master's Program in Odontological Sciences mention Oral Pathology. Principal tutor Student Mauricio Baeza Paredes 2014. Financing: FONDECYT 1120138.
6. Systemic inflammation in serum of patients with asymptomatic apical periodontitis. Master's Program in Odontological Sciences mention Oral Pathology. Principal tutor Student Fabián Obregón Miano year 2014. Financing: FONDECYT 1120138.
7. Effect of extracellular matrix metalloproteinases on TNF levels ?; IL-1 ?; SDF-1 / CXCL12 and VEGF in human periodontal ligament fibroblasts stimulated with hydrogen peroxide. Research work to qualify for the Master's degree in Dental Sciences. Program: Master in Cs. Dentistry mention Periodontology, University of Chile, Student: Franco Cavalla. 2013. Main tutor. Financing: FONDECYT 1090461.
8. Effect of H2O2 on the activity of alkaline phosphatase, cytokine and extracellular matrix metalloproteinase levels with osteolytic activity in human periodontal ligament fibroblasts, Magister in Cs. Dentistry mention Periodontology, University of Chile, Faculty of Dentistry. Student: Constanza Osorio 2012. Funding: FONDECYT 1090461.
9. Levels and Activity of Extracellular Matrix Metalloproteinases -2, -9, -13 and? 2-macroglobulin in teeth with Chronic Apical Periodontitis. Magister program in Cs. Dentistry mention Periodontology, University of Chile, Student (a): Verónica Mundi, 2012. Financing: FONDECYT 1090461.


Premios y Distinciones

  •   2012 Odontological Research Award

    COLGATE PALMOLIVE CHILE S.A

    Chile, 2012

    Award for Dental Research 2012, Colgate-Palmolive Chile, Santiago Chile. December 19, 2012.

  •   Academic Recognition Germán Valenzuela Basterrica in Research". III Conference of Internal Reflection: Good Teaching Practices "Academic Direction

    UNIVERSIDAD DE CHILE

    Chile, 2012

    Recognition in Dental Research awarded by academic peers


Tipos de Producción
 

Conference Paper (87)

Aspectos Morfológicos y Biología de la Anquilosis de la ATM
Biomarcadores en FCG en diagnóstico de sitios superficiales en periodontitis
Dendritic cells response upon coninfection with different Aggregatibacter actinomycenetcomitans serotypes
Inflamación sistémica en pacientes con periodontitis apical asintomática Infectados con Porphyromonas endodontalis
MMP-8 ,TRAP5 y OPG biomarcadores de periodontitis crónica en sus estados iniciales
Niveles de marcadores proinflamatorios y endotoxina en lesiones apicales de Periodontitis Apical Sintomática
RANKL/OPG ratio and TRAP in Symptomatic and Asymptomatic Apical Lesions
Análisis de presentación de fertilidad de equinococosis quística y de distomatosis en bovinos faenados en la Región Metropolitana
Caracterización morfológica de anquilosis de articulación temporomandibular
Caracterización morfológica de granuloma de células gigantes
Distribución de Lesiones Prevalentes No-inducidas-por-placa-bacteriana según clasificación AAP
H2O2 induce MMPs a través de NFkB y Señales de Calcio en Fibroblastos Periodontales
Inflamación Sistémica, Disfunción Endotelial y Endotoxemia en Periodontitis Apical Asintomática
Lesiones Gingivales No inducidas por Placa Bacteriana: Prevalencia a 20 años en chilenos. (IREPO, 1990-2009)
Reactive Protein is synthesized in Apical Lesions of Endodontic Origin
Aggregatibacter actinomycetencomitans and Porphyromonas gingivalis serotypes associated with chronic periodontitis
Análisis del Fluido Gingival Crevicular en Periodontitis Apical
Collagenolytic MMPs and Myeloperoxidase as Biomarkers of Periodontal Diseases
Endotoxina y MMP-8 en lesiones apicales endodónticas y ligamento apical
Frecuencia de Lesiones Gingivales no Inducidas por Placa Bacteriana
Frequency of Non-Plaque-Induced Gingival Lesions (Santiago, Chile)
GCF biomarkers in apical and marginal periodontal chronic inflammation
H2O2 induces Inflammatory Changes in human periodontal ligament fibroblasts (PDLF)
Interleuquina-6 y Proteína C Reactiva en Lesiones Apicales Endodónticas
Linfocitos Th9, Th17 y T reg en la periodonto-patogénesis
Mieloperoxidasa en Exudado Periapical de Dientes con Patologías Periapicales
Mieloperoxidasa en exudado periapical pre y post preparación quimiomecánica endodóntica
Moléculas solubles de adhesión en lesiones apicales de origen endodóntico
Morphologic characterization of temporomandibular joint ankylosis
MPO en lesiones apicales de origen endodóntico
Niveles de Endotoxinas Sistémicas en Pacientes con Periodontitis Crónica
Presencia y niveles en dientes con patologías periapicales
Quimioquinas CC y Receptores CCR en Salud o Enfermedad Periodontal
SDF-1/CXCL12 in periapical lesions od endodontic origin
Síntesis de RANKL por linfocitos T CD4+ ante distintos serotipos bacteriano
Temporomandibular Joint Ankylosis: A Clinical Study
Asociación entre periodontitis crónica y síndrome metabólico, revisión de la literatura de la última década
Caracterización de MMP-8 y marcadores de destrucción ósea eb periodontitis apical crónica
Characterization of MMPs and Alpha-2-macroglobulin in asymptomatic apical periodontitis
Efecto de dosis subantimicrobianas de doxiciclina como coadyuvante del tratamiento periodontal no quirúrgico
Factor derivado de células estromales-1, SDF-1/CXCL 12, en lesiones apicales de origen endodóntico
Frequency of oral squamous cell carcinoma and epitelial displasia: IREPO, University of Chile, 1990-2009
H2O2 induces MMPs via NF-kB pathway in periodontal ligament fibroblasts
MMP-12: Presence and semiquantificationin periapical exudates during endodontic therapy
Rol de los mastocitos en la etiopatogenia de las lesiones apicales
SDF-1/CXCL12 in asymptomatic apical periodontitis
Balance oxidativo y actividad gelatinolítica en periodontitits apical asintomática
Determination of VEGF in apical lesions and gingival crevicular fluid
Evaluation of Periodontal Response to ozone therapy in GCF
Frecuencia de lesiones gingivales no asociadas a placa bacteriana
Gelatinasas y Colagenasas en la Patogenia de las Lesiones Periapicales
H2O2 induces MMPs and NFκB signaling in periodontal ligament fibroblasts
MMP-12 Posible rol en la etiopatogenia de las lesiones periapicales en dientes con periodontitis apical asintomática
MMP-12: Levels and immunolocalization in periapical lesions of endodontic origin
MMPs -8, -2 and -9 in endodontic periapical lesions
Pathogen and mast cell identification in absceced apical granulomas
Pro-oxidative status in endodontic apical lesions and gingival crevicular fluid
Rol del factor de transcripcional RUNX2 como modulador de la expresión de MMPs en la migración e invasión celular de osteosarcoma
SDF-1/CXCL12 in asymptomatic apical periodontitis and gingival crevicular fluid levels
TNF-α in gingival crevicular fluid of subjects with apical periodontitis
VEGF levels and oxidative stress in periodontal ligament and chronic apical periodontitis lesions
Aislación y caracterización de fibroblastos de ligamento periodontal
Association between MMP-8 and myeloperoxidase in progressive chronic periodontitis
Characterization of MMP-2, MMP-9, ICTP and SDF-1 in chronic apical periodontitis
H2O2 stimulates MMP gelatinolytic Activity in fibroblasts from periodontal ligament
Lesiones periapicales: Nuevos conceptos y perspectivas futuras
MMP-8, TIMP-1 and Myeloperoxidase as biomarkers of periodontal diseases
MMPs-13 y -13 en dientes con lesiones apicales en sujetos con periodontitis crónica
Niveles de TNF-α y RANKL en fluido crevicular gingival de piezas dentarias con periodontitis apical crónica
Oxidative status and MMPs -2 and -9 in Apical lesions
Estudio Molecular de la Patología Endodóntica

Article (68)

Adjunctive Effects of a Sub-Antimicrobial Dose of Doxycycline on Clinical Parameters and Potential Biomarkers of Periodontal Tissue Catabolism
Elevated Systemic Inflammatory Burden and Cardiovascular Risk in Young Adults with Endodontic Apical Lesions
Expression of Toll-like receptors 2 and 4 and its association with matrix metalloproteinases in symptomatic and asymptomatic apical periodontitis
New insights of the local immune response against both fertile and infertile hydatid cysts
Capsular-defective Porphyromonas gingivalis mutant strains induce less alveolar bone resorption than W50 wild-type strain due to a decreased Th1/Th17 immune response and less osteoclast activity
Comparative Study of the Minichromosome Maintenance Proteins Complex (MCM 4/5/6) in Ameloblastoma and Unicystic Ameloblastoma
Diagnosis of Newly Delivered Mothers for Periodontitis with a Novel Oral-Rinse aMMP-8 Point-of-Care Test in a Rural Malawian Population
Distribution of biopsied non plaque-induced gingival lesions in a Chilean population according to the classification of periodontal diseases
Echinococcus granulosus hydatid cyst location is modified by Fasciola hepatica infection in cattle
Expression of hMLH1 and hMSH2 proteins in ameloblastomas and tooth germs
First description of Echinococcus ortleppi and cystic echinococcosis infection status in Chile
Human periodontal ligament fibroblasts synthesize C-reactive protein and Th-related cytokines in response to interleukin (IL)-6 trans-signalling
Periodontitis and placental growth factor in oral fluids are early pregnancy predictors of gestational diabetes mellitus
Treponema denticola chymotrypsin-like proteinase is present in early-stage mobile tongue squamous cell carcinoma and related to the clinicopathological features
Treponema denticola chymotrypsin-like proteinase may contribute to orodigestive carcinogenesis through immunomodulation
Bone resorptive activity in symptomatic and asymptomatic apical lesions of endodontic origin
Matrix Metalloproteinases as Regulators of Periodontal Inflammation
Quantification of Chemokine CCL5 in Patients with Diabetes Mellitus Type 2 and/or Chronic Periodontitis: Preliminary Study
Analysis of matrix metalloproteinases, especially MMP-8, in gingival creviclular fluid, mouthrinse and saliva for monitoring periodontal diseases
Association of Endodontic Lesions with Coronary Artery Disease
Clinical Effects of Lactobacillus rhamnosus in Non-Surgical Treatment of Chronic Periodontitis: A Randomized Placebo-Controlled Trial With 1-Year Follow-Up
Diagnostic accuracy for apical and chronic periodontitis biomarkers in gingival crevicular fluid: an exploratory study
Frecuencia de displasia epitelial y carcinoma escamoso en mucosa oral y orofaríngea en Chile, entre los años 1990 y 2009
Actividad de metaloproteinasa de matriz extracelular-9 en fluido crevicular gingival durante la respuesta reparativa en peridodontitis apical asintomática
C-Reactive Protein Expression Is Up-regulated in Apical Lesions of Endodontic Origin in Association with Interleukin-6
Evaluación de lesiones periapicales de origen endodóntico mediante tomografía computada cone beam
H2O2 activates matrix metalloproteinases through the nuclear factor kappa B pathway and Ca2+ signals in human periodontal fibroblasts
Host response mechanisms in periodontal diseases
Matrix metalloproteinases regulate extracellular levels of SDF-1/CXCL12, IL-6 and VEGF in hydrogen peroxide-stimulated human periodontal ligament fibroblasts
DL-2-Hydroxyisocaproic Acid Attenuates Inflammatory Responses in a Murine Candida albicans Biofilm Model
Genetic Variation on the BAT1-NFKBIL1-LTA Region of Major Histocompatibility Complex Class III Associates with Periodontitis
Host-derived biomarkers of apical periodontitis in gingival crevicular fluid: a potential side-diagnostic tool
Interferon-gamma, Interleukins-6 and -4, and Factor XIII-A as Indirect Markers of the Classical and Alternative Macrophage Activation Pathways in Chronic Periodontitis
Matrix metalloproteinase-8 regulates transforming growth factor-beta 1 levels in mouse tongue wounds and fibroblasts in vitro
Matrix metalloproteinases and myeloperoxidase in gingival crevicular fluid provide site-specific diagnostic value for chronic periodontitis
Serotype-dependent response of human dendritic cells stimulated with Aggregatibacter actinomycetemcomitans
Estudio de confiabilidad de la prueba de sialometría para flujo no estimulado en sujetos adultos clínicamente sanos
High Levels of CXC Ligand 12/Stromal Cell-derived Factor 1 in Apical Lesions of Endodontic Origin Associated with Mast Cell Infiltration
Interleukin-21 Expression and Its Association With Proinflammatory Cytokines in Untreated Chronic Periodontitis Patients
Pro-oxidant status and matrix metalloproteinases in apical lesions and gingival crevicular fluid as potential biomarkers for asymptomatic apical periodontitis and endodontic treatment response
Asociación entre niveles de TNF-? en fluido crevicular gingival de dientes con periodontitis apical asintomática
Collagenase-2 (MMP-8) as a point-of-care biomarker in periodontitis and cardiovascular diseases. Therapeutic response to non-antimicrobial properties of tetracyclines
Inmunodetección de metaloproteinasas de matriz extracelular (MMPs)-2, -9, -13 y -14 en lesiones apicales asociadas con periodontitis apical asintomática
Levels of Interleukin-21 in Patients With Untreated Chronic Periodontitis
Oral rinse MMP-8 point-of-care immuno test identifies patients with strong periodontal inflammatory burden
Reduced expression of lipopolysaccharide-induced CXC chemokine in Porphyromonas gingivalis-induced experimental periodontitis in matrix metalloproteinase-8 null mice
Associations Between Matrix Metalloproteinase-8 and -14 and Myeloperoxidase in Gingival Crevicular Fluid From Subjects With Progressive Chronic Periodontitis: A Longitudinal Study
Chemokine Monocyte Chemoattractant Protein-3 in Progressive Periodontal Lesions in Patients With Chronic Periodontitis
Detection of gingival crevicular fluid MMP-8 levels with different laboratory and chair-side methods
Monocyte chemotactic protein-3: possible involvement in apical periodontitis chemotaxis
Efecto del tratamiento periodontal no quirúrgico en los niveles de MMP-2 y TIMP-2 en periodontitis crónica
Expresión de CCL7 y CCR5 en lesiones periapicales
Expresión de Factor Estimulante de Colonias-1 (CSF-1) y Catepsina-K en Lesiones Periapicales
Levels of Interferon-Gamma and Transcription Factor T-Bet in Progressive Periodontal Lesions in Patients With Chronic Periodontitis
MMPs en la Patogenia de la Periodontitis Apical Crónica: Destrucción o Protección de los Tejidos Periapicales?
Proteolytic roles of matrix metalloproteinase (MMP)-13 during progression of chronic periodontitis: initial evidence for MMP-13/MMP-9 activation cascade
Soluble forms of MMP-14 and CXCL12 expression in progressive chronic periodontitis
Characterization of progressive periodontal lesions in chronic periodontitis patients: levels of chemokines, cytokines, matrix metalloproteinase-13, periodontal pathogens and inflammatory cells
Gelatinolytic activity in gingival crevicular fluid from teeth with periapical lesions
Perfiles proteicos y peptídicos en periodontitis crónica
MMP-13 and TIMP-1 determinations in progressive chronic periodontitis
High expression levels of receptor activator of nuclear factor-kappa B ligand associated with human chronic periodontitis are mainly secreted by CD4(+) T lymphocytes
ICTP levels in chronic periodontitis patients and its association with disease progression
Matrix metalloproteinase-13 is highly expressed in destructive periodontal disease activity
Torres-Quintana MA. Matrix metalloproteinases and their role in the alteration of the osseointegration process
Ameloblastin and amelogenin expression in posnatal developing mouse molars.
Regulación de la expresión génica de TNF-Alfa
Patología de la mucosa oral en adultos mayores. Instituto de Referencia de Patología Oral (IREPO), Santiago, Chile

Dtp Import/Article (31)

Matrix metalloproteinases regulate extracellular levels of SDF-1/CXCL12, IL-6 and VEGF in hydrogen peroxide-stimulated human periodontal ligament fibroblasts
BAT1-NFKBIL1-LTA OF MHC CLASS III IS A PREDISPOSING GENE REGION TO PERIODONTITIS
DL-2-Hydroxyisocaproic Acid Attenuates Inflammatory Responses in a Murine Candida albicans Biofilm Model
Genetic Variation on the BAT1-NFKBIL1-LTA Region of Major Histocompatibility Complex Class III Associates with Periodontitis
Interferon-gamma, Interleukins-6 and -4, and Factor XIII-A as Indirect Markers of the Classical and Alternative Macrophage Activation Pathways in Chronic Periodontitis
Interferon-gamma, Interleukins-6 and -4, and Factor XIII-A as Indirect Markers of the Classical and Alternative Macrophage Activation Pathways in Chronic Periodontitis
Matrix metalloproteinase-8 regulates transforming growth factor-beta 1 levels in mouse tongue wounds and fibroblasts in vitro
Matrix metalloproteinases and myeloperoxidase in gingival crevicular fluid provide site-specific diagnostic value for chronic periodontitis
Serotype-dependent response of human dendritic cells stimulated with Aggregatibacter actinomycetemcomitans
High Levels of CXC Ligand 12/Stromal Cell-derived Factor 1 in Apical Lesions of Endodontic Origin Associated with Mast Cell Infiltration
Interleukin-21 Expression and Its Association With Proinflammatory Cytokines in Untreated Chronic Periodontitis Patients
Pro-oxidant status and matrix metalloproteinases in apical lesions and gingival crevicular fluid as potential biomarkers for asymptomatic apical periodontitis and endodontic treatment response
Collagenase-2 (MMP-8) as a point-of-care biomarker in periodontitis and cardiovascular diseases. Therapeutic response to non-antimicrobial properties of tetracyclines
Host-Pathogen Interactions in Progressive Chronic Periodontitis
Levels of Interleukin-21 in Patients With Untreated Chronic Periodontitis
MMP activation in diagnostics of periodontitis and systemic inflammation
Oral rinse MMP-8 point-of-care immuno test identifies patients with strong periodontal inflammatory burden
Reduced expression of lipopolysaccharide-induced CXC chemokine in Porphyromonas gingivalis-induced experimental periodontitis in matrix metalloproteinase-8 null mice
Associations Between Matrix Metalloproteinase-8 and -14 and Myeloperoxidase in Gingival Crevicular Fluid From Subjects With Progressive Chronic Periodontitis: A Longitudinal Study
Chemokine Monocyte Chemoattractant Protein-3 in Progressive Periodontal Lesions in Patients With Chronic Periodontitis
Detection of gingival crevicular fluid MMP-8 levels with different laboratory and chair-side methods
Levels of interleukin-21 in apical periodontitis and their association with disease pathogenesis and clinical symptomatology
Monocyte chemotactic protein-3=> possible involvement in apical periodontitis chemotaxis
Levels of Interferon-Gamma and Transcription Factor T-Bet in Progressive Periodontal Lesions in Patients With Chronic Periodontitis
Characterization of progressive periodontal lesions in chronic periodontitis patients=> levels of chemokines, cytokines, matrix metalloproteinase-13, periodontal pathogens and inflammatory cells
Gelatinolytic activity in gingival crevicular fluid from teeth with periapical lesions
MMP-13 and TIMP-1 determinations in progressive chronic periodontitis
High expression levels of receptor activator of nuclear factor-kappa B ligand associated with human chronic periodontitis are mainly secreted by CD4(+) T lymphocytes
Matrix metalloproteinase-13 is highly expressed in destructive periodontal disease activity
Ameloblastin and amelogenin expression in postnatal developing mouse molars
A quantitative point-of-care test for periodontal and peri-implant diseases

Review (3)

Oxidative Stress in the Local and Systemic Events of Apical Periodontitis
Análisis de MMPs en fluidos orales en el diagnóstico complementario de las enfermedades periodontales
Host-Pathogen Interactions in Progressive Chronic Periodontitis

Abstract (3)

BAT1-NFKBIL1-LTA OF MHC CLASS III IS A PREDISPOSING GENE REGION TO PERIODONTITIS
Levels of interleukin-21 in apical periodontitis and their association with disease pathogenesis and clinical symptomatology
Ameloblastin and amelogenin expression in postnatal developing mouse molars

Book Section (2)

Components of Host Response to Pathogenic Bacteria in Gingivitis, Components of Host Response to Pathogenic Bacteria in Gingivitis

Letter (2)

A quantitative point-of-care test for periodontal and dental peri-implant diseases
MMP activation in diagnostics of periodontitis and systemic inflammation
165
Emma Hernández

Académico 44 h, profesor titular

Oral Patology and Medicine

Universidad de Chile, Facultad de Odontología

SANTIAGO, Chile

22
Rolando Vernal

Profesor Asociado

Departamento de Odontología Conservadora

UNIVERSIDAD DE CHILE

Santiago, Chile

18
Jorge Gamonal

PROFESOR TITULAR

ODONTOLOGIA CONSERVADORA

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

9
Timo Sorsa

Visiting Professor of Oral Biology

Institute of Dentistry

Karolinska Institutet

Stockholm, Suecia

6
Taina Tervahartiala

Research Scientist

Biomedicum-Institute of Dentistry

Universidad de Helsinki

Helsinki, Finlandia

4
Patricia Pozo

Académico

Ciencias Farmacéuticas

UNIVERSIDAD CATÓLICA DEL NORTE

Antofagasta, Chile

3
Loreto Abusleme

Assistant Professor

Oral pathology and medicine

FACULTAD DE ODONTOLOGÍA, UNIVERSIDAD DE CHILE

Santiago, Chile

3
Franco Cavalla

Assistant professor

Conservative dentistry

Universidad de Chile

Santiago, Chile

3
Juan Aguillón

PROFESSOR

IMMUNOLOGY PROGRAM

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

2
Rodolfo Paredes

Ungraduated General Director

Academic Vice Rectory

UNIVERDAD ANDRÉS BELLO

Santiago, Chile

2
Ana Ortega

Associate Professor

Pathology and Oral Medicine

UNIVERSIDAD DE CHILE, FACULTAD DE ODONTOLOGÍA

Santiago, Chile

1
Andrea Paula

Assistant Professor

Institute for research in Dental Sciences

Universidad de Chile

Santiago, Chile

1
Alicia Morales

Docente

Conservadora

Facultad de Odontología, Universidad de Chile

Santiago, Chile

1
Paola Carvajal

Profesora Asistente

Odontologia Conservadora

FACULTAD DE ODONTOLOGÍA UNIVERSIDAD DE CHILE

Santiago, Chile

1
Johanna Contreras

Profesor Asistente

Odontología Conservadora

UNIVERSIDAD DE CHILE

Santiago, Chile

1
JUAN AITKEN

PROFESOR ASISTENTE

PATOLOGIA Y MEDICINA ORAL

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Marcela Alcota

Profesora Asistente

Odontologia Conservadora

Universidad de Chile

Santiago, Chile

1
Victor Martinez

Profesor de tiempo completo

Periodoncia

Universidad Autonoma de Yucatan

Merida, Chile

1
MANUEL VARAS

Assistant Professor

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

1
Alejandra Chaparro

Profesora Titular

Odontología

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

1
Arnoldo Hernandez

Académico

Anatomia y Medicina Legal

Universidad de Chile

Santiago, Chile

1
Sebastián Illanes

professor, Director of Reproductive Biology Laboratory

Medicine

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

1
Octavio Aravena

INVESTIGADOR

INSTITUTO CIENCIAS BIOMÉDICAS

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Stephanie Acuña

Asistente de Investigación

Facultad de Medicina

Universidad de los Andes

Santiago, Chile