Man

Alejandra Beatriz Alvarez Rojas

Full professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

Líneas de Investigación


My research line is focused on understanding the molecular mechanisms involved in neurodegenerative diseases. Our results support a key role of dysregulated c-Abl signaling in Alzheimer and Niemann Pick diseases.

Educación

  •  Biochemistry, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1989
  •  Cell and Molecular Biology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1998

Experiencia Académica

  •   Researcher Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Santiago, Chile

    Enero 2016 - A la fecha

  •   Researcher Part Time

    Basal Center for Aging and Regeneration CARE CHILE UC

    Biological Sciences

    Santiago, Chile

    Enero 2013 - Sin Información

  •   Cloister member Other

    UNIVERSIDAD DE CHILE

    Santiago, Chile

    Enero 2012 - A la fecha

  •   Chief of PhD program Other

    Cell and Molecular Biology PhD program

    Biological Sciences

    Santiago, Chile

    Enero 2010 - Enero 2014

  •   Associate Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Biological Sciences

    Santiago, Chile

    Enero 2010 - Enero 2016

  •   Cloister member. Cell and Molecular Biology PhD program. Other

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Biological Sciences

    Santiago, Chile

    Enero 2002 - A la fecha

  •   Assistant Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Biological Sciences

    Santiago, Chile

    Enero 2002 - Enero 2010

  •   Research in Formation Biochemical Cytology Laboratory Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Biological Sciences

    Santiago, Chile

    Enero 1990 - Enero 1991

  •   Postdoctorate Full Time

    UNIVERSIDAD DE CHILE

    Sciences Faculty

    Santiago, Chile

    Enero 1998 - Enero 2000

  •   Full Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Biological Sciences

    Santiago, Chile

    Enero 2017 - A la fecha

Experiencia Profesional

  •   Researcher Part Time

    Center of the Nanotechnology and advanced Materials CIEN UC

    Santiago, Chile

    Enero 2016 - A la fecha

  •   Researcher Part Time

    Basal Center for Aging and Regeneration CARE CHILE UC

    Santiago, Chile

    Enero 2013 - A la fecha

  •   Director Part Time

    Chilean FONDEF D10E1077, Preclinical studies of new inhibitors of c-Abl kinase for the treatment of Alzheimer's disease

    Santiago, Chile

    Enero 2017 - A la fecha

  •   co-Investigator Other

    Chilean Redes 150082, LysosHead: Lysosomes signaling in health and disease. PI Silvana Zanlungo

    Santiago, Chile

    Enero 2016 - A la fecha

  •   Research Associate Full Time

    FONDAP-BIOMEDICINA UC

    Santiago, Chile

    Enero 2000 - Enero 2002

  •   Director Part Time

    FONDEF D10I1077 Identification of inhibitors of c-Abl kinase for the potential treatment of Alzheimer's Disease

    Santiago, Chile

    Enero 2011 - Enero 2014

Formación de Capital Humano


Training and formation.
Undergraduate Collective Courses:
2003-2008, Teacher (collaborator) Biology of the Cell (BIO-141C). For Biochemistry, Bachelor in Sciences and Agronomy.
2005-2008, and 2017 Teacher (in charge) Biology of the Cell (BIO-141C) for Pharmaceutical Chemistry.
2009-2016, Teacher (in charge) Biochemistry and Cell Biology Laboratory (BIO-297C) for Bachelor in Sciences and collaborator in: Biology of the Cell (BIO-141C) and Molecular Pathology (BIO-241C) for Biochemist and Bachelor in Sciences and Molecular Biology of the Cell (BIO-238) for Medicine
2016-present Teacher (in charge) Biology of the Cell (BIO-141C). For Chemistry and Pharmacy.
2002-present, Every year several one semester research units for Biology and Biochemist undergraduate students.
Postgraduate Collective Courses (DBCM PhD program):
2002- present, Teacher (collaborator) Course Cell Biology (BIO444A)
2008-present, Teacher (in charge) Course Signaling pathways in neurodegenerative diseases (BIO-4104)
2012 Teacher (collaborator) Cellular and Molecular Bases of Neurobiology (BIO4103)
THESIS DIRECTION
UNDERGRADUATE BIOLOGICAL SCIENCES BACHELOR THESIS (FINISHED): 10
BIOCHEMISTRY THESIS (FINISHED): 11
BIOLOGICAL SCIENCES PHD THESIS: 12 Finished and 6 (In Progress)
PhD students
1. April 2008 - Mary Carmen Vazquez. Cell and Molecular Biology PhD program. Biological Sciences Faculty, P. Universidad Católica de Chile. c-Abl kinase modulates the AICD activity in the presence of adapter protein FE65 (co-tutoring Dr. Inestrosa).
2. June 2009 - Andres Klein. Cell and Molecular Biology PhD program. Biological Sciences Faculty, P. Universidad Católica de Chile. c-Abl/p73 signal transduction pathway in Niemann-Pick disease type C (co-tutoring Dra. Silvana Zanlungo).
3. September 2009 - Ignacio Cancino Lobos. Cell and Molecular Biology PhD program. Biological Sciences Faculty, P. Universidad Católica de Chile. The c-Abl tyrosine kinase in Alzheimer disease: its role in Neuronal death and cytoskeleton alterations.
4. January 2010 - Karen G. Perez de Arce. Cell and Molecular Biology PhD program. Biological Sciences Faculty, P. Universidad Católica de Chile. The c-Abl tyrosine kinase regulates the PSD-95 synaptic accumulation and modulates the number of synaptic contacts hippocampal neurons.
5. July 2010, Veronica Codelia. Cell and Molecular Biology PhD program. Biological Sciences Faculty, P. Universidad Católica de Chile. Dual role of p73 protein during spermatogenesis: effects in differentiation and apoptosis.
6. July 2010 – Lisbell Estrada A. Biological Sciences PhD Program, Biological Sciences Faculty, Universidad de Chile. Seeding of oligomer, new strategies for Alzheimer's diagnosis and possible implications for the progression of the disease, Director thesis Claudio Soto. Co-director: Alejandra Alvarez.
7. June 2011 - Lina Vargas Rojas. Cell and Molecular Biology PhD program. Biological Sciences Faculty, P. Universidad Católica de Chile. Ephrin A4 receptor/c-Abl kinase signaling mediates the A? oligomers sinaptotoxicity.
8. September 2014 - Marcelo González. Cell and Molecular Biology PhD program. Biological Sciences Faculty, P. Universidad Católica de Chile. c-Abl induce HDAC2 tyrosine phosphorylation and neuronal genes repression in Alzheimer diseases models.
9. January 2016 - Maria Jose Yañez. Cell and Molecular Biology PhD program. Biological Sciences Faculty, P. Universidad Católica de Chile. Tyrosine kinase c-Abl modulates the amyloid precursor protein processing and its implication for Niemann Pick Type C. Tutor: Alejandra Alvarez. Co-tutor Dra. Silvana Zanlungo.
10. Noviembre 2016, Alexis Martínez Saavedra, Cell and Molecular Biology PhD program. Biological Sciences Faculty, P. Universidad Católica de Chile. C-Abl kinase phosphorylates mitofusin-2 modulating the mitochondrial dynamics and apoptosis; potential role of c-abl in amyotrophic lateral sclerosis. Director: Alejandra Alvarez
11. Agosto 2017, Francisco Morales Zavala, PhD Program in Biochemistry, Chemical and Pharmaceutical Sciences Faculty, Universidad de Chile. Gold nanoparticles modified with peptides: Biodistribution and effects on the aggregation of ?-amyloid. Director Marcelo Kogan, co-tutor Alejandra Alvarez.
12. Enero de 2019, Pablo Contreras. Titulo del proyecto de Tesis: ““TYROSINE KINASE ABL INHIBITION ACTIVATES TFEB AND PROMOTES CELLULAR CLEARANCE IN NIEMANN-PICK C DISEASE”. Tutor: Alejandra Álvarez y Dra. Silvana Zanlungo. Programa de Doctorado en Biología Celular y Molecular. Facultad de Ciencias Biológicas, P. Universidad Católica de Chile.
13. Diciembre 2017 Tesis de Magister David Chamorro. OBTENCIÓN DE NANOPARTÍCULAS DE ORO MULTIFUNCIONALIZADAS CON EL INHIBIDOR DE LA QUINASA C-ABL, GNF-2 Y EL PÉPTIDO ANGIOPEP-2 (ANGIOPEP-2-NVOS-GNF2) PARA PREVENIR LA NEURODEGENERACIÓN EN MODELOS DE LA ENFERMEDAD DE ALZHEIMER. Magister en Bioquímica, toxicología y diagnostico molecular. Facultad de Ciencias Químicas Universidad de Chile

Postdocs
1. 2005 Julio Amigo (PhD Cell and Molecular Biology and Neurosciences, Faculty of Sciences, U Chile).
2. 2007- 2008 Lorena Varela (PhD in Cell and Molecular Biology, Biological Sciences Faculty PUC, FONDECYT-Post-doctorate 3070017).
3. 2007- 2008 co-direction Carola Maldonado (PhD in Chemical and Pharmaceutical Sciences, UCH).
4. 2010 -2012 Lisbell Estrada (PhD in Cell Biology, Faculty of Sciences, U. FONDECYT-Postdoctorate 3110052).
5. 2011-2013 Lina Vargas Rojas (PhD in Cell and Molecular Biology, Biological Sciences Faculty PUC. FONDECYT Post-doctorate 33120015).
6. 2017 Ignacio Cancino (PhD in Cell and Molecular Biology, Biological Sciences Faculty PUC).


Premios y Distinciones

  •   Alvarez Alejandra

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 1985

    Undergraduate “Honor Student Award”, PUC for the best Biochemist student 1985

  •   Alvarez Alejandra

    COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

    Chile, 1992

    Graduate scholarship

  •   Alvarez Alejandra

    FUNDACION CIENCIA PARA LA VIDA

    Chile, 1998

    Best Ph.D Thesis 1998

  •   Alvarez Alejandra and Zanlungo Silvana

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2008

    Best Patent presented 2008

  •   Inestrosa Nibaldo, Alvarez Alejandra

    The FEBS Journal

    Chile, 2008

    2008 Top-cited Paper Award The FEBS Journal


Tipos de Producción
 

Dtp Import/Article (55)

Glutamatergic stimulation induces GluN2B translation by the nitric oxide-Heme-Regulated eIF2α kinase in cortical neurons.
Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway
Anti-ribosomal p protein autoantibodies from patients with neuropsychiatric lupus impair memory in mice
Characterizing HSF1 Binding and Post-Translational Modifications of hsp70 Promoter in Cultured Cortical Neurons: Implications in the Heat-Shock Response.
Mitochondrial-produced reactive oxygen species that activate c-Abl signaling trigger motoneuron death in non-cell-autonomous models of ALS
P73 and P63: The siblings that work together in neurodevelopment.
Physiological Control of Nitric Oxide on neuronal BACE1 Translation by Heme-Regulated Eif2 alpha Kinase HRI Induces Synaptogenesis.
c-Abl stabilizes HDAC2 levels by tyrosine phosphorylation repressing neuronal gene expression in Alzheimer's disease
EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-b oligomers
The unique case of the Niemann-Pick type C cholesterol storage disorder
Vitamin E dietary supplementation improves neurological symptoms and decreases c-Abl/p73 activation in Niemann-Pick C mice
Cholinergic abnormalities, endosomal alterations and up-regulation of nerve growth factor signaling in Niemann-Pick type C disease.
Increased copper levels in in vitro and in vivo models of Niemann-Pick C disease
Increased copper levels in in vitro and in vivo models of Niemann-Pick C disease.
Lysosomal vitamin E accumulation in Niemann–Pick type C disease
Oxidative stress: a pathogenic mechanism for Niemann-Pick type C disease.
c-Abl tyrosine kinase modulates tau pathology and Cdk5 phosphorylation in AD transgenic mice
C-Abl Tyrosine Kinase Signaling: A New Player in AD Tau Pathology
Corticotropin-releasing factor binding protein enters the regulated secretory pathway in neuroendocrine cells and cortical neurons
Lack of Activation of the Unfolded Protein Response in Mouse and Cellular Models of Niemann-Pick Type C Disease
Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons
Tetrahydrohyperforin prevents cognitive deficit, Abeta deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1deltaE9 model of Alzheimer's disease: a possible effect on APP processing.
p73 participates in male germ cells apoptosis induced by etoposide
Synaptic Clustering of PSD-95 Is Regulated by c-Abl through Tyrosine Phosphorylation
Alzheimer s beta-amyloid deposits induce the c-Abl/p73 signaling in AD models.
c-Abl Modulates AICD Dependent Cellular Responses: Transcriptional Induction and Apoptosis
Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function
Amyloid-cholinesterase interactions - Implications for Alzheimer s disease
Heparin activates Wnt signaling for neuronal morphogenesis
Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease
STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer s beta-amyloid deposits
Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse.
Acetylcholinesterase-amyloid-beta-peptide interaction: effect of Congo Red and the role of the Wnt pathway.
Activation of the neuronal c-Abl tyrosine kinase by amyloid-beta-peptide and reactive oxygen species.
Wnt-3a overcomes beta-amyloid toxicity in rat hippocampal neurons.
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils.
Protein kinase C inhibits amyloid beta peptide neurotoxicity by acting on members of the Wnt pathway.
Wnt signaling involvement in beta-amyloid-dependent neurodegeneration.
A cdk5-p35 stable complex is involved in the beta-amyloid-induced deregulation of cdk5 activity in hippocampal neurons
Acetylcholinesterase-amyloid-beta-peptide interaction and Wnt signaling involvement in Abeta neurotoxicity.
Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death.
Molecular modeling of the amyloid-beta-peptide using the homology to a fragment of triosephosphate isomerase that forms amyloid in vitro.
Regulatory roles of microtubule-associated proteins in neuronal morphogenesis. Involvement of the extracellular matrix.
Brain acetylcholinesterase promotes amyloid-beta-peptide aggregation but does not hydrolyze amyloid precursor protein peptides.
Laminin blocks the assembly of wild-type A beta and the Dutch variant peptide into Alzheimer's fibrils.
Stable complexes involving acetylcholinesterase and amyloid-beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils.
A monoclonal antibody against acetylcholinesterase inhibits the formation of amyloid fibrils induced by the enzyme.
Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils.
Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.
Acetylcholinesterase is a senile plaque component that promotes assembly of amyloid beta-peptide into Alzheimer’s filaments
Laminin inhibits amyloid-beta-peptide fibrillation.
Acetylcholinesterase, a senile plaque component, affects the fibrillogenesis of amyloid-beta-peptides.
Characterization of human peroxisomal membrane proteins.
Isolation of peroxisomes from frozen human liver samples.

Grant (27)

Center for Aging and Regeneration (CARE)
Characterization of Peroxisomal membrane proteins
Genesis of Helical Paired Strands (PHF) in Alzheimer's Disease
GNF-2/GNF-5 chemical derivatives for the treatment of Alzheimer disease
Identification of inhibitors of c-Abl kinase for the potential treatment of Alzheimer's Disease
Induction of β-amyloid peptide aggregation by acetylcholinesterase
LysosHead: Lysosomes Signaling in Health and Disease
Nano-devices for high-precision measurements in biology and nanostructured materials of biomedical interest
Project. Porins of S. Typhi
Relevance of the Niemann pick C proteins in physiology and pathophysiology
Signalling pathways leading to neuronal death in NPC: finding new therapeutics targets

Article (25)

Lysosome motility and distribution: Relevance in health and disease.
Amyloid-beta oligomers synaptotoxicity: The emerging role of EphA4/c-Abl signaling in Alzheimers disease
Functionalization of stable fluorescent nanodiamonds towards reliable detection of biomarkers for Alzheimers disease
MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content
Peptide multifunctionalized gold nanorods decrease toxicity of beta-amyloid peptide in a Caenorhabditis elegans model of Alzheimer's disease
c-Abl links APP-BACE1 interaction promoting APP amyloidogenic processing in Niemann-Pick type C disease
Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway
Reduction of Blood Amyloid-? Oligomers in Alzheimer?s Disease Transgenic Mice by c-Abl Kinase Inhibition
Anti-Ribosomal P Protein Autoantibodies From Patients With Neuropsychiatric Lupus Impair Memory in Mice
Characterizing HSF1 Binding and Post-Translational Modifications of hsp70 Promoter in Cultured Cortical Neurons: Implications in the Heat-Shock Response
Physiological Control of Nitric Oxide in Neuronal BACE1 Translation by Heme-Regulated eIF2 alpha Kinase HRI Induces Synaptogenesis
Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling
The unique case of the Niemann-Pick type C cholesterol storage disorder
c-Abl tyrosine kinase modulates tau pathology and Cdk5 phosphorylation in AD transgenic mice
C-Abl Tyrosine Kinase Signaling: A New Player in AD Tau Pathology
Corticotropin-releasing factor binding protein enters the regulated secretory pathway in neuroendocrine cells and cortical neurons
Lack of Activation of the Unfolded Protein Response in Mouse and Cellular Models of Niemann-Pick Type C Disease
Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons
p73 participates in male germ cells apoptosis induced by etoposide
Synaptic Clustering of PSD-95 Is Regulated by c-Abl through Tyrosine Phosphorylation
c-Abl Modulates AICD Dependent Cellular Responses: Transcriptional Induction and Apoptosis
Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function
Heparin activates Wnt signaling for neuronal morphogenesis
Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease
STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's beta-amyloid deposits

Generic (1)

Alzheimer's beta-amyloid deposits induce the c-Abl/p73 signaling in AD models.

Review (1)

Amyloid-cholinesterase interactions - Implications for Alzheimer's disease
56
Alejandra Alvarez

Full professor

Cell and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

10
Silvana Zanlungo

Full Professor

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

8
Nibaldo Inestrosa

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

6
Gonzalo Cancino

Assistant Professor

Facultad de Ciencias

Universidad Mayor

Santiago, Chile

4
Ivan Alfaro

Associate Researcher

Basal Financing Program for Scientific and Technological Centers of Excellence

Fundación Ciencia y Vida

Santiago, Chile

4
Andrés Klein

Assistant Professor/Director (Head) Center for Genetics and Genomics

Centro de Genética y Genómica

Universidad del Desarrollo-Clínica Alemana

SANTIAGO, Chile

3
Katia Gysling

Professor

Cellular and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Rommy Von Bernhardi

Full Professor

Neurology

DEPT. NEUROLOGY, FAC. MEDICINE PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Marcelo Kogan

Academico

Quimica Farmacologica y Toxicologica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

2
Francisco Morales

Posdoctoral

Universidad de Chile. Centro FONDAP ACCDiS

Santiago, Chile

2
Lorena Varela

Assistant Professor

Biological Sciences

Universidad Andres Bello

Santiago, Chile

2
Maria Andres

Full Professor

Cellular and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Enrique Brandan

Profesor Titular

Biología Celular y Molecular

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

2
Lisbell Estrada

Directora de Investigacion y Doctorados

Universidad Bernardo O Higgins

santiago, Chile

1
Nicole Cortes

Asistente de Investigación

Laboratorio de Biología Celular, Molecular y Neurociencias, Corporación Centro Internacional de Biomedicina, ICC

Santiago, Chile

1
Natalia Hassan

Académico

Universidad Tecnológica Metropolitana

Santiago, Chile

1
Francisca Bronfman

Associate Professor

Physiology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FAC. CS. BIOLÓGICAS, DEPTO. FISIOLOGÍA

Santiago, Chile

1
Ricardo Moreno

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS, DEPTO. DE FISIOLOGÍA

Santiago, Chile

1
Felipe Court

Director

Center for Integrative Biology

Universidad Mayor

Huechuraba, Chile

1
Alvaro Elorza

ASSOCIATE PROFESSOR

CENTER FOR BIOMEDICAL RESEARCH

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Andrea Gómez

Investigador Postdoctoral

Fisiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Alfonso González

Full Professor

School of Medicine

Universidad San Sebastián

Santiago, Chile

1
Juan Pablo Henriquez

Associate Professor

Cell Biology

UNIVERSIDAD DE CONCEPCIÓN, FACULTAD DE CIENCIAS BIOLÓGICAS, DEPARTAMENTO DE BIOLOGÍA CELULAR

Concepción, Chile

1
Eyleen Araya

Academic

Chemical Sciences

Universidad Andres Bello

santiago, Chile

1
Julio Amigo

Assistant Professor

Physiology

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Rebeca Aldunate

UNIVERSIDAD SANTO TOMÁS

Santiago, Chile

1
Simon Guerrero

Investigador Postdoctoral

Departamento de Química Farmacológica y Toxicológica

Universidad de Chile

Santiago, Chile

1
Nathalie Casanova

Postdoctorado

Facultad de Ingeniería y Ciencias

Universidad Adolfo Ibañez

Santiago, Chile

1
Waldo Cerpa

Profesor Asociado

Biología Celular y Molecular

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Fanny Guzman

Investigador Senior

Núcleo de Biotecnología Curauma

Pontificia Universidad Católica de Valparaiso

Valparaiso, Chile

1
Alicia Nogueras

Profesor Asociado Adjunto

Departamento de Biología Celular y Molecular

P. UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Mario Favre

Profesor Titular

Instituto de Física, Pontificia Universidad Católica de Chile

Santiago, Chile

1
Jeronimo Maze

Associate Professor

Physics

FACULTAD DE FISICA, PONTIFICIA UNIVERSIDAD CATOLICA

Santiago, Chile