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Ian Franco Cavalla Ruiz

Assistant professor

Universidad de Chile

Santiago, Chile

Immunology of periodontal diseases Genetics Osteoimmunology Clinical trails Periodontal treatment Implant dentistry Periodontal Regeneration Bone Regeneration

Dentist, UNIVERSIDAD DE CHILE. Chile, 2004
Periodontics, UNIVERSIDAD DE CHILE. Chile, 2011
Periodontics, UNIVERSIDAD DE CHILE. Chile, 2013
Oral biology and stomatology, UNIVERSIDADE DE SAO PAULO. Brasil, 2017

Associate Professor Part Time

UNIVERSIDAD DE CHILE

Dentistry

Santiago, Chile

2013 - A la fecha

Dentist EDF Full Time

SSVSA

Algarrobo, Chile

2005 - 2009
Associate professor Part Time

Universidad de Chile

Santiago, Chile

2013 - A la fecha
Periodoncista Part Time

SSA Hospital San Camilo

San Felipe, Chile

2018 - A la fecha
Director Other

Clínica Cavalla

Santiago, Chile

2021 - A la fecha

Best paper in clinical research

Journal of Endodontics

Estados Unidos, 2019

Best scientific paper 2019 in the category 'Clinical research' for: Investigating Potential Correlations between Endodontic Pathology and Cardiovascular Diseases Using Epidemiological and Genetic Approaches. J Endod. 2019 Feb;45(2):104-110. doi: 10.1016/j.joen.2018.10.014. Epub 2019 Jan 17.


Bioactive glass-ceramic bone repair associated or not with autogenous bone=> a study of organic bone matrix organization in a rabbit critical-sized calvarial model. Biguetti, Claudia Cristina; Cavalla, Franco; Tim, Carla Roberta; Saraiva, Patrícia Pinto; Orcini, Wilson; De Andrade Holgado, Leandro; Rennó, Ana Claudia Muniz; Matsumoto, Mariza Akemi Article Clinical oral investigations (2019)
Investigating Potential Correlations between Endodontic Pathology and Cardiovascular Diseases Using Epidemiological and Genetic Approaches. Messing, Maria; Souza, Letícia Chaves de; Cavalla, Franco; Kookal, Krishna Kumar; Rizzo, Gabriella; Walji, Muhammad; Silva, Renato; Letra, Ariadne Article Journal of endodontics (2019)
CCR2 Contributes to F4/80+Cells Migration Along Intramembranous Bone Healing in Maxilla, but Its Deficiency Does Not Critically Affect the Healing Outcome Biguetti, CC; Vieira, AE; Cavalla, F; Fonseca, AC; Colavite, PM; Silva, RM; Trombone, APF; Garlet, GP Article FRONTIERS IN IMMUNOLOGY (2018)
CCR5 Delta 32 (rs333) polymorphism is associated with decreased risk of chronic and aggressive periodontitis: A case-control analysis based in disease resistance and susceptibility phenotypes Cavalla, F; Biguetti, CC; Dionisio, TJ; Azevedo, MCS; Martins, W; Santos, CF; Trombone, APF; Silva, RM; Letra A.; Garlet, GP Article ISI CYTOKINE (2018)
Colorectal Cancer-Associated Genes Are Associated with Tooth Agenesis and May Have a Role in Tooth Development Williams, Meredith A.; Biguetti, Claudia; Romero-Bustillos, Miguel; Maheshwari, Kanwal; Dinckan, Nuriye; Cavalla, Franco; Liu, Xiaoming; Silva, Renato; Akyalcin, Sercan; Uyguner, Z. Oya; Vieira, Alexandre R.; Amendt, Brad A.; Fakhouri, Walid D.; Letra, Ariadne Article SCIENTIFIC REPORTS (2018)
Genetic Association with Subgingival Bacterial Colonization in Chronic Periodontitis Franco Cavalla, Claudia Cristina Biguetti; Jessica Lima Melchiades, Andre Pantenuci Tabanez; Michelle de Campos Soriani Azevedo, Ana Paula Favaro Trombone; Marcelo Faveri, Magda Feres Article GENES (2018)
CCR5δ32 (rs333) polymorphism is associated with decreased risk of chronic and aggressive periodontitis: A case-control analysis based in disease resistance and susceptibility phenotypes Cavalla F.; Biguetti C.C.; Dionisio T.J.; Azevedo M.C.S.; Martins Jr W.; Santos C.F.; Trombone A.P.F.; Silva R.M.; Letra A.; Garlet G.P. Article SCOPUS Cytokine (2017)
Characterization of a Vascular Endothelial Growth Factor-loaded Bioresorbable Delivery System for Pulp Regeneration Yadlapati M.; Biguetti C.; Cavalla F.; Nieves F.; Bessey C.; Bohluli P.; Garlet G.P.; Letra A.; Fakhouri W.D.; Silva R.M. Article ISI SCOPUS JOURNAL OF ENDODONTICS (2017)
Matrix Metalloproteinases as Regulators of Periodontal Inflammation Franco, Cavalla; Patricia, Hernández-Ríos; Timo, Sorsa; Claudia, Biguetti; Marcela, Hernández Article International Journal of Molecular Sciences (2017)
Proteomic Profiling and Differential Messenger RNA Expression Correlate HSP27 and Serpin Family B Member 1 to Apical Periodontitis Outcomes Cavalla F.; Biguetti C.; Jain S.; Johnson C.; Letra A.; Garlet G.P.; Silva R.M. Article ISI SCOPUS JOURNAL OF ENDODONTICS (2017)
Influence of TNF-?-308 G/A gene polymorphism on temporomandibular disorder Furquim B.D.; Flamengui L.M.S.P.; Repeke C.E.P.; Cavalla, F; Garlet G.P.; Conti P.C.R. Article ISI SCOPUS American Journal of Orthodontics and Dentofacial Orthopedics (2016)
MMP1-1607 polymorphism increases the risk for periapical lesion development through the upregulation MMP-1 expression in association with pro-inflammatory milieu elements Trombone A.P.F.; Cavalla F.; Silveira E.M.V.; Andreo C.B.; Francisconi C.F.; Fonseca A.C.; Letra A.; Silva R.M.; Garlet G.P. Article ISI SCOPUS JOURNAL OF APPLIED ORAL SCIENCE (2016)
H2O2 activates matrix metalloproteinases through the nuclear factor kappa B pathway and Ca2+ signals in human periodontal fibroblasts Osorio C.; Cavalla, F; Paula Lima A.; Diaz-Araya, G; Vernal, R; Ahumada P.; Gamonal, J; Hernandez, M. Article ISI SCOPUS JOURNAL OF PERIODONTAL RESEARCH (2015)
Matrix metalloproteinases regulate extracellular levels of SDF-1/CXCL12, IL-6 and VEGF in hydrogen peroxide-stimulated human periodontal ligament fibroblasts Cavalla, F; Osorio C.; Paredes, R.; Valenzuela, MA.; Garcia-Sesnich, J; Sorsa, T.; Tervahartiala, T.; Hernandez, M. Article ISI SCOPUS Cytokine (2015)
Strategies to Direct the Enrichment, Expansion, and Recruitment of Regulatory Cells for the Treatment of Disease Glowacki, AJ; Gottardi, R; Yoshizawa, S; Cavalla, F; Garlet, GP; Sfeir C.; Little, SR Article ISI SCOPUS Annals of Biomedical Engineering (2015)
TBX21-1993T/C (rs4794067) polymorphism is associated with increased risk of chronic periodontitis and increased T-bet expression in periodontal lesions, but does not significantly impact the IFN-g transcriptional level or the pattern of periodontophatic bacterial infection Cavalla, F; Biguettii, CC; Colavite, PM; Silveira, EV; Martins, W; Letra A.; Trombone, APF; Silva, RM; Garlet, GP Article ISI SCOPUS Virulence (2015)
Simultaneous analysis of T helper subsets (Th1, Th2, Th9, Th17, Th22, Tfh, Tr1 and Tregs) markers expression in periapical lesions reveals multiple cytokine clusters accountable for lesions activity and inactivity status Araujo-Pires, AC; Francisconi, CF; Biguetti, CC; Cavalla, F; Aranha, AMF; Letra A.; Trombone, APF; Faveri, M; Silva, RM; Garlet, GP Article ISI SCOPUS JOURNAL OF APPLIED ORAL SCIENCE (2014)
High Levels of CXC Ligand 12/Stromal Cell-derived Factor 1 in Apical Lesions of Endodontic Origin Associated with Mast Cell Infiltration Cavalla, F; Reyes, M; Vernal, R; Alvarez C.; Paredes, R.; Garcia-Sesnich, J; Infante, M; Farina, V; Barron, I; Hernandez, M. Article ISI SCOPUS Journal of Endodontics (2013)
High levels of SDF-1/CXCL12 in apical lesions of endodontic origin associates with mast cell infiltration Cavalla F, Reyes M; Vernal R, Álvarez C; Paredes R, García-Sesnich J; Infante M, Fariña V; Barrón I, Hernández M Article Journal of Endodonthics (2013)


Examen Dental Preventivo Adulto Mayor (EDePAM) con Control del Riesgo y de las Complicaciones de las Enfermedades Crónicas No Transmisibles=> Mejorando la calidad de vida del adulto mayor chileno FONDEF (ID18I10034) Proyecto 2018-2020 Coinvestigador(a)
Influência de polimorfismos genéticos nos padrões de colonização e recolonização bacteriana em pacientes com periodontite crônica FAPESP (2014/03276-0) Proyecto 2013-2017 Tesista
CROSSTALK BETWEEN LOCAL HOST RESPONSE TO ENDODONTIC INFECTION AND LOW-GRADE SYSTEMIC INFLAMMATION IN ASYMPTOMATIC APICAL PERIODONTITIS=> PROSPECTIVE STUDY EVALUATING THE EFFECT OF CONSERVATIVE ENDODONTIC TREATMENT FONDECYT (1120138) Proyecto 2012-2016 Tesista
CHARACTERIZATION OF OXIDANT STATUS AND MMP-MEDIATED PROTEOLYSIS DURING PROGRESSION OF APICAL PERIODONTITIS IN GINGIVAL CREVICULAR FLUID=> A NEW TOOL IN THE SEARCH OF EARLY PROGNOSTIC MARKERS? FONDECYT (1090461) Proyecto 2009-2012 Tesista