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Victor Antonio Cortes Mora

Associate professor

Pontificia Universidad Católica de Chile

Santiago, Chile

1.Cellular and molecular determinants of adipose tissue differentiation and maintenance. 2. Endocrine, metabolic and genetic characterization of individuals with severe insulin resistance syndromes. 3. Molecular basis of fatty liver disease

Medical Sciences, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2005
Physician surgeon, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2001
Medicine, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2000

Postdoctoral scholar Full Time

UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS

Dallas, Estados Unidos

2006 - 2011
Instructor Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicine

Santiago, Chile

2011 - 2012
Assistant Professor Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicine

Santiago, Chile

2012 - 2015
Associate professor Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicine

Santiago, Chile

2016 - A la fecha

Attending physician - diabetology, general medicine Full Time

Pontificia Universidad Católica de Chile

Chile

2005 - A la fecha
Attending physician Part Time

Hospital Sótero del Río, Ministry of Health

Chile

2005 - 2006
Postodoctoral fellow Full Time

University of Texas Southwestern Medical Center

Estados Unidos

2006 - 2011
Integrante grupo de estudio Fondecyt Medicina G1 Other

Conicyt

Chile

2016 - 2019

A. Postdoctoral fellows:
1) Pablo Mardones, PhD (University of Amesterdam, Netherlands), Pontificia Universidad Católica de Chile 2012-2013
2) Marta Fernandez, PhD (University of Navarra, Spain), Pontificia Universidad Católica de Chile 2015-2018
3) Marcela Fuentes, PhD (Unversity of Chile, Chile), Pontificia Universidad Católica de Chile 2015-2018

B. PhD thesis:
1) Kelly Cautivo. Biological Sciences Doctoral Program, Molecular Genetics and Microbilogy mention, Pontificia Universidad Católica de Chile, graduated in 2014.
2) Pablo Tapia. Biological Sciences Doctoral Program, Molecular Genetics and Microbilogy mention, Pontificia Universidad Católica de Chile. In progress, to be graduated in 2019.
3) Lila González, Medical Sciences, Pontificia Universidad Católica de Chile. In progress, to be graduated in 2020.
4) Fermín Robledo, Biotechnology. Universidad Nacional Andrés Bello. In progress, to be graduated in 2019.
5) Ana María Figueroa, Medical Sciences, Pontificia Universidad Católica de Chile. 2019 - in progress.
6) Luis R. Cataldo. Biomedical Sciences Doctoral Program, Universidad de los Andes - Chile. Graduated in 2015.
7) Juan Carlos Bórquez, Nutrition and Food Doctoral program, University of Chile, co-director, 2020 - in progress
8) Patricio Medel, Epidemiology Doctoral Program, Pontificia Universidad Católica de Chile. co-director, 2020 - in progress

C. Magister thesis:
1) Denisse Goldenberg, Master in Nutrition, Pontificia Universidad Católica de Chile. Graduated in 2013
2) María J. Riveros, Master in Nutrition, Pontificia Universidad Católica de Chile. Graduated in 2014
3) Ana María Figueroa, Master in Nutrition, Pontificia Universidad Católica de Chile. Graduated in 2017
4) Pía Zamora, Master in Nutrition, Pontificia Universidad Católica de Chile. Graduated in 2017
5) Beatriz Villanueva, Master in Nutrition, Pontificia Universidad Católica de Chile. Graduated in 2018
6) Caterina Tiscornia, Master in Nutrition, Pontificia Universidad Católica de Chile. To be graduated in 2021
7) Luisa Mejía, Master in Nutrition, Pontificia Universidad Católica de Chile. To be graduated in 2022
8) Maricarmen García, Master in Nutrition, Pontificia Universidad Católica de Chile. To be graduated in 2022

D. Undergraduate students:
1) Alejandro Jeldres, Medical Student, Pontificia Universidad Católica de Chile, 2012-2013
2) Karen García, Medical Student, Pontificia Universidad Católica de Chile, 2012-2013
3) Roberto Coloma, Medical Student, Pontificia Universidad Católica de Chile, 2012-2013
4) Elizabeth Muñoz, Medical Student, Pontificia Universidad Católica de Chile, 2012-2013
5) Judith Huichaqueo, Biotechnology Engineering, Universidad Nacional Andrés Bello, Chile, 2020-2021

- Explora - Conicyt, High school talks, students and teachers´ supervision: 2012 - to date
- Study group - member, Fondecyt Medicine G1: 2015-2019
- Study group - director, Fondecyt Medicine G1: 2017 - 2019
- Memberships: Chilean society of endocrinology and diabetes, Chilean society of cellular biology, Chilean society of nutrition and toxicology

Honor Scholarship

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile, 1993

Awareded for the highest academic performance at the Medical School
Honor Scholarship

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile, 1994

Awareded for the highest academic performance at the Medical School
Honor Scholarship

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile, 1995

Awareded for the highest academic performance at the Medical School
Doctoral felloswhip

MINISTRY OF EDUCATION, CULTURE, SPORTS, SCIENCE AND TECHNOLOGY

Chile, 2001

Awarded for funding doctoral studies
Doctoral felloswhip

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile, 2004

Awarded for funding doctoral studies
President of the Republic Fellowship

Ministry of planification and coorperation

Chile, 2006

Awarderd for international postdoctoral studies
Postdoctoral fellowship

American Heart Association

Estados Unidos, 2009

For postdoctoral research


Decreased caveolae in AGPAT2 lacking adipocytes is independent of changes in cholesterol or sphingolipid levels: a whole cell and plasma membrane lipidomic analysis of adipogenesis Gonzalez-Hodar, Lila; McDonald, Jeffrey; Vale, Goncalo; Thompson Bonne; Figueroa;,Ana-Maria; Tapia, Pablo; Robledo, Fermin; Agarwal, Anil K.; Garg, Abhimanyu; Jay D Horton; Cortés, Víctor Article Biochimica et Biophysica Acta - Molecular Basis of Disease (2021)
Eating behaviour in contrasting adiposity phenotypes: Monogenic obesity and congenital generalized lipodystrophy Santos, Jose L.; Cortes, Victor A. Article ISI OBESITY REVIEWS (2021)
Insulin resistance and liver histopathology in metabolically unhealthy subjects do not correlate with the hepatic abundance of NLRP3 inflammasome nor circulating IL-1β levels Quezada, Nicolas; Valencia, Ilse; Torres, Javiera; Maturana, Gregorio; Cerda, Jaime; Arab, Juan P.; Fuentes, Juan J.; Pinto, Claudio; Turiel, Dannae; Cortés, Víctor A. Article BMJ OPEN DIABETES RESEARCH AND CARE (2021)
Absence of AGPAT2 impairs brown adipogenesis, increases IFN stimulated gene expression and alters mitochondrial morphology Tapia, Pablo J.; Figueroa, Ana-Maria; Eisner, Veronica; Gonzalez-Hodar, Lila; Robledo, Fermin; Agarwal, Anil K.; Garg, Abhimanyu; Cortes, Victor Article ISI METABOLISM-CLINICAL AND EXPERIMENTAL (2020)
Insulin increases cholesterol uptake, lipid droplet content, and apolipoprotein B secretion in CaCo-2 cells by upregulating SR-BI via a PI3K, AKT, and mTOR-dependent pathway Fuentes, M; Santander N.; Cortes, V Article ISI SCOPUS JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
Abdominal obesity is a common finding in normal and overweight subjects of Chile and is associated with increased frequency of cardiometabolic risk factors Villanueva, B; Arteaga, A; Maiz, A; Cortes, VA Article ISI SCOPUS PLOS ONE (2018)
Nonalcoholic fatty liver disease, cholesterol gallstones, and cholecystectomy: new insights on a complex relationship Arrese, Marco; Cortés, Víctor; Barrera ,Francisco; Nervi, Flavio Article ISI SCOPUS CURRENT OPINION IN GASTROENTEROLOGY (2018)
Effect of cholecystectomy on hepatic fat accumulation and insulin resistance in non-obese Hispanic patients: a pilot study Cortés, Víctor; Quezada, Nicolás; Uribe, Sergio; Arrese, Marco; Nervi, Flavio Article ISI SCOPUS LIPIDS IN HEALTH AND DISEASE (2017)
Effect of cholecystectomy on hepatic fat accumulation and insulin resistance in non-obese Hispanic patients=> a pilot study Cortés, Víctor; Quezada, Nicolás; Uribe, Sergio; Arrese, Marco; Nervi, Flavio Article Lipids in health and disease (2017)
Expression of SREBP-1c requires SREBP-2-mediated generation of a sterol ligand for LXR in livers of mice Rong S.; Cortés V.A.; Rashid S.; Anderson N.N.; McDonald J.G.; Liang G.; Moon Y.-A.; Hammer R.E.; Horton J.D. Article SCOPUS eLife (2017)
Expression of SREBP-1c requires SREBP-2-mediated generation of a sterol ligand for LXR in livers of mice Rong, S; Cortés, VA; Rashid, S; Anderson, NN; McDonald, JG; Liang, G; Moon, YA; Hammer, RE; Horton, JD Article eLife (2017)
Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cell Cataldo, LR; Mizgier, ML; Sagua, RB; Jaña, F; Cárdenas, C; Llanos, P; Busso, D; Olmos, P; Galgani, JE; Santos, JL; Cortés, VA Article PLoS One (2017)
AGPAT2 is essential for postnatal development and maintenance of white and brown adipose tissue Cautivo K.M.; Lizama C.O.; Tapia P.J.; Agarwal A.K.; Garg, A; Horton J.D.; Cortés V.A. Article ISI SCOPUS Molecular Metabolism (2016)
AGPAT2 is essential for postnatal development and maintenance of white and brown adipose tissue Cautivo, KM; Lizama, CO; Tapia, PJ; Agarwal, AK; Garg, A; Horton, JD Article Molecular Metabolism (2016)
Serotonin- and Dopamine-Related Gene Expression in db/db Mice Islets and in MIN6 Beta-Cells Treated with Palmitate and Oleate Cataldo, LR; Mizgier, ML; Busso, D; Olmos, P; Galgani, JE; Valenzuela, R; Mezzano, D; Aranda, E; Cortés, VA; Santos, JL Article Journal of Diabetes Research (2016)
AGPAT2 deficiency impairs adipogenic differentiation in primary cultured preadipocytes in a non-autophagy or apoptosis dependent mechanism Fernández-Galilea M, Tapia P; Cautivo K, Morselli E Article BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
AGPAT2 deficiency impairs adipogenic differentiation in primary cultured preadipocytes in a non-autophagy or apoptosis dependent mechanism Fernandez-Galilea, M; Tapia, P; Cautivo, K.; Morselli E.; Cortes, VA Article ISI SCOPUS Biochemical and Biophysical Research Communications (2015)
Fluoxetine Impairs Insulin Secretion without Modifying Extracellular Serotonin Levels in MIN6 beta cells Cataldo LR, Cortés VA; Mizgier ML, Aranda E; Mezzano D, Olmos P; Galgani JE, Suazo J Article EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2015)
Fluoxetine Impairs Insulin Secretion without Modifying Extracellular Serotonin Levels in MIN6 beta-cells Cataldo, LR; Cortes, VA; Mizgier, ML; Aranda, E; Mezzano D.; Olmos, P; Galgani, JE; Suazo, J; Santos, JL Article ISI SCOPUS Experimental and Clinical Endocrinology and Diabetes (2015)
Lipodystrophies=> adipose tissue disorders with severe metabolic implications Cortés VA, Fernandez-Galilea M Article JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (2015)
Metabolic Effects of Cholecystectomy: Gallbladder Ablation Increases Basal Metabolic Rate through G-Protein Coupled Bile Acid Receptor Gpbar1-Dependent Mechanisms in Mice Corts, Vctor; Amigo, Ludwig; Zanlungo, Silvana.; Galgani, José; Robledo, Fermn; Arrese, Marco; Bozinovic, Francisco; Nervi, Flavio; Alpini, Gianfranco Article ISI SCOPUS PLOS ONE (2015)
Metabolic effects of cholecystectomy=> gallbladder ablation increases basal metabolic rate through G-protein coupled bile acid receptor Gpbar1-dependent mechanisms in mice Cortés V, Amigo L; Zanlungo S, Galgani J; Robledo F, Arrese M; Bozinovic F, Nervi F Article Plos One (2015)
Asociación entre diabetes mellitus y patología cardiovascular en la población adulta de Chile: estudio de la Encuesta Nacional de Salud 2009-2010 Antonio Arteaga; Alberto Maiz; Attilio Rigotti; V Cort Article SCIELO SCOPUS REVISTA MEDICA DE CHILE (2014)
Asociación entre diabetes mellitus y patología cardiovascular en la población adulta de Chile=> estudio de la Encuesta Nacional de Salud 2009-2010 Arteaga A, Maiz A; Rigotti A, Cortés V Article Revista Médica de Chile (2014)
Association between diabetes mellitus and cardiovascular disease in Chilean adults. Analysis of the national health survey 2009-2010 Arteaga A.; Maiz A.; Rigotti, A.; Cortés V. Article ISI REVISTA MEDICA DE CHILE (2014)
Divergent Metabolic Phenotype between Two Sisters with Congenital Generalized Lipodystrophy Due to Double AGPAT2 Homozygous Mutations. A Clinical, Genetic and In Silico Study Cortés, Víctor A.; Smalley, Susan V.; Goldenberg, Denisse; Lagos, Carlos F; Hodgson, María I.; Santos, Jose L.; Moro, Cedric Article ISI SCOPUS PLOS ONE (2014)
Divergent metabolic phenotype between two sisters with congenital generalized lipodystrophy due to double AGPAT2 homozygous mutations. a clinical, genetic and in silico study. Cortés VA, Smalley SV; Goldenberg D, Lagos CF; Hodgson MI, Santos JL. Article Plos one (2014)
Leptin ameliorates insulin resistance and hepatic steatosis in Agpat2(-/-) lipodystrophic mice independent of hepatocyte leptin receptors Cortes, VA; Cautivo, KM; Rong, SX; Garg, A; Horton, JD; Agarwal, AK Article ISI SCOPUS JOURNAL OF LIPID RESEARCH (2014)
Leptin ameliorates insulin resistance and hepatic steatosis in Agpat2-/- lipodystrophic mice independent of hepatocyte leptin receptors. Cortés VA, Cautivo KM; Rong S, Garg A; Horton JD, Agarwal AK. Article Journal of lipid research (2014)
Leptin ameliorates insulin resistance and hepatic steatosis in Agpat2-/- lipodystrophic mice independent of hepatocyte leptin receptors. Cortés, VA; Cautivo, KM; Rong, S; Garg, A; Horton, JD; Agarwal, AK. Article Journal of lipid research (2014)
Novel physiological and therapeutic implications of leptin [Nuevas proyecciones fisiológicas, patológicas y terapéuticas de la leptina] Goldenberg D.; Santos, J.L.; Hodgson M.I.; Cortés V.A. Article SCOPUS Revista Medica de Chile (2014)
Nuevas proyecciones fisiológicas y terapéuticas de la leptina Goldenberg D, Hogdson MI; Santos JL, Cortés V. Article Revista Médica de Chile (2014)
Papel de la serotonina periférica en la secreción de insulina y la homeostasis de la glucosa Cataldo, LR; Cortés VA, Galgani JE; Olmos PR, Santos JL Article Nutr Hosp (2014)
Physiological and pathological implications of cholesterol Cortes, VA; Busso, D.; Maiz A.; Arteaga A.; Nervi, F; Rigotti, A. Article ISI SCOPUS FRONTIERS IN BIOSCIENCE-LANDMARK (2014)
Physiological and pathological implications of cholesterol. Cortes, Victor A; Busso, Dolores; Maiz, Alberto; Arteaga, Antonio; Nervi, Flavio; Rigotti, Attilio Article Frontiers in bioscience (Landmark edition) (2014)
Advances in the physiological and pathological implications of cholesterol. Cortes, VA; Busso, D; Mardones, P; Maiz, A; Arteaga, A; Nervi, F Article Biological reviews of the Cambridge Philosophical Society (2013)
The contribution of Goldstein and Brown to the study of cholesterol metabolism [Rememorando la contribución de Goldstein y Brown al estudio del metabolismo del colesterol=> A un cuarto de siglo del Premio Nobel de Medicina Cortés, V.; Vásquez, T.; Arteaga, A.; Nervi, F.; Rigotti, A. Article Revista Medica de Chile (2012)
Human 1-Acylglycerol-3-phosphate O-Acyltransferase isoforms 1 and 2: Biochemical characterization and inability to rescue hepatic steatosis in Agpat2 -/- gene lipodystrophic mice Agarwal A.K.; Sukumaran S; Tunison K.; Sankella S.; Garg, A; Horton J.D.; Mizrachi D.; Gerard R.D.; Cortés V.A. Article JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Human 1-Acylglycerol-3-phosphate O-Acyltransferase isoforms 1 and 2=> Biochemical characterization and inability to rescue hepatic steatosis in Agpat2 -/- gene lipodystrophic mice Agarwal, AK; Sukumaran, S; Cortés, VA; Tunison, K; Mizrachi, D; Sankella, S; Gerard, RD; Horton, JD; Garg, A. Article Journal of Biological Chemistry (2011)
Npc1 deficiency in the C57BL/6J genetic background enhances Niemann-Pick disease type C spleen pathology Parra J.; Klein, AD; Castro J.; Morales, MG; Mosqueira, M; Valencia I.; Cortés V.; Rigotti, A.; Zanlungo S. Article ISI SCOPUS Biochemical and Biophysical Research Communications (2011)
Npc1 deficiency in the C57BL/6J genetic background enhances Niemann-Pick disease type C spleen pathology Parra, J; Klein, AD; Castro, J; Morales, MG; Mosqueira, M; Valencia, I; Cortés, VA; Rigotti, A; Zanlungo, S. Article Biochemical and Biophysical Research Communications (2011)
Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor alpha (LXR alpha) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1 Grefhorst, A; Schreurs, M; Oosterveer, MH; Cortés, VA; Havinga, R; Herling, AW; Reijngoud, DJ; Groen, AK; Kuipers, F. Article Biochemical Journal (2010)
Molecular Mechanisms of Hepatic Steatosis and Insulin Resistance in the AGPAT2-Deficient Mouse Model of Congenital Generalized Lipodystrophy Cortés, VA; Curtis, DE; Sukumaran, S; Shao, X; Parameswara, V; Rashid, S; Smith, AR; Ren, J; Esser, V; Hammer, RE; Agarwal, AK; Horton, JD; Garg, A Article Cell Metabolism (2009)
NO production and eNOS phosphorylation induced by epinephrine through the activation of beta-adrenoceptors Figueroa, XF; Poblete, I; Fernandez, R.; Pedemonte, C; Cortés V.; Huidobro-Toro, JP Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
NO production and eNOS phosphorylation induced by epinephrine through the activation of beta-adrenoceptors. Figueroa, XF; Poblete, I; Fernández, R; Pedemonte, C; Cortés, V; Huidobro-Toro, JP Article American journal of physiology. Heart and circulatory physiology (2009)
Adenovirus-mediated hepatic syndecan-1 overexpression induces hepatocyte proliferation and hyperlipidaemia in mice Cortés V.; Amigo, L; Donoso K.; Valencia I.; Quiñones V.; Zanlungo S.; Brandan, E.; Rigotti, A. Article ISI SCOPUS LIVER INTERNATIONAL (2007)
Adenovirus-mediated hepatic syndecan-1 overexpression induces hepatocyte proliferation and hyperlipidaemia in mice. Cortés, Víctor; Amigo, Ludwig; Donoso, Katherine; Valencia, Ilse; Quiñones, Verónica; Zanlungo, Silvana; Brandan, Enrique; Rigotti, Attilio Article Liver international => official journal of the International Association for the Study of the Liver (2007)
Increased expression of syndecan-1 protects against cardiac dilatation and dysfunction after myocardial infarction Vanhoutte, D; Schellings, MWM; Gotte, M; Swinnen, M; Herias, V; Wild, MK; Vestweber, D; Chorianopoulos, E; Cortés V.; Rigotti, A.; Stepp, MA; Van de Werf, F; Carmeliet, P; Pinto, YM; Heymans, S Article ISI SCOPUS CIRCULATION (2007)
Increased expression of syndecan-1 protects against cardiac dilatation and dysfunction after myocardial infarction. Vanhoutte, Davy; Schellings, Mark W M; Götte, Martin; Swinnen, Melissa; Herias, Veronica; Wild, Martin K; Vestweber, Dietmar; Chorianopoulos, Emmanuel; Cortés, Víctor; Rigotti, Attilio; Stepp, Mary-Ann; Van de Werf, Frans; Carmeliet, Peter; Pinto, Yigal M; Heymans, Stephane Article Circulation (2007)
Liver heparan sulfate proteoglycans: Old molecules provide new insights on lipoprotein metabolism - Commentary Cortés V.; Rigotti, A. Article HEPATOLOGY (2007)
Liver heparan sulfate proteoglycans=> old molecules provide new insights on lipoprotein metabolism. Cortés, Víctor; Rigotti, Attilio Article Hepatology (Baltimore, Md.) (2007)
[New heterodimeric nuclear receptors=> key metabolic regulators with relevance in the pathophysiology and therapy of dyslipidemias and diabetes mellitus]. Cortés, Víctor; Quezada, Nicolás; Rigotti, Attilio; Maiz, Alberto Article Revista mÃ©dica de Chile (2005)
Nuevos receptores nucleares heterodiméricos: reguladores metabólicos con impacto en fisiopatología y su proyección terapéutica en dislipidemias y diabetes mellitus Cortés, Víctor; Quezada, Nicolas; Rigotti, Attilio; Maiz, Alberto Article SCIELO REVISTA MEDICA DE CHILE (2005)
Synergism between neuropeptide Y and norepinephrine highlights sympathetic cotransmission: Studies in rat arterial mesenteric bed with neuropeptide Y, analogs, and BIBP 3226 Cortés V.; Donoso, M. V.; Brown, N; Fanjul R.; López C.; Huidobro-Toro J.P.; Fournier, A. Article JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (1999)
Stimulation of the sympathetic perimesenteric arterial nerves releases neuropeptide Y potentiating the vasomotor activity of noradrenaline: Involvement of neuropeptide Y-Y 1 receptors Donoso, M. V.; Brown, N; Carrasco C.; Cortés V.; Huidobro-Toro J.P.; Fournier, A. Article JOURNAL OF NEUROCHEMISTRY (1997)


Insulin regulates SRBI and ABCG8 in a mTOR dependent pathway in CaCo-2 cells Fuentes, M; Santander, N; Cortes, V Abstract ISI (2016)
STRATEGIES FOR SEARCHING GENETIC CAUSES OF NUTRITION-RELATED EXTREME METABOLIC PHENOTYPES Santos, JL; Cortés V.; Zanlungo S.; Miquel, JF Abstract ANNALS OF NUTRITION AND METABOLISM (2013)
Adenovirus-mediated hepatic overexpression of syndecan-1 increases plasma lipoprotein cholesterol without changes in liver and biliary cholesterol content in mice Cortés V.; Donoso K.; Amigo, L; Zanlungo S.; Brandan, E.; Rigotti, A. Abstract CIRCULATION (2005)


Carbohydrate, Fat, and Protein Metabolism in Obesity Galgani, José; Cortés, Víctor; Carrasco, Fernando.; Ahima, Rexford BookSection (2016)


Genetics of body composition: From severe obesity to extreme leanness Santos J.L.; CortÃ©s V. BookWhole ISI SCOPUS Principles of Nutrigenetics and Nutrigenomics: Fundamentals of Individualized Nutrition (2019)
Manual de dislipidemias. Metabolismo y clínica Artega, Antonio; Maiz, Alberto; Rigotti, Attilio; Cortés, Víctor BookWhole (2016)


ROLE OF MITOCHONDRIA AND CAVEOLAE LIPID COMPOSITION ON AGPAT2-DEPENDENT LIPODYSTROPHY Cortés, Víctor; Eisner, Verónica Proyecto (2018)
Association between gene variants of the mitochondrial genome and proteome with insulin secretion/sensitivity indexes and glycemic-related traits FONDECYT (1150416) Proyecto 2015-2018 Coinvestigador(a)
ASSOCIATION BETWEEN GENE VARIANTS OF THE MITOCHONDRIAL GENOME AND PROTEOME WITH INSULIN SECRETION/SENSITIVITY INDEXES AND GLYCEMIC-RELATED TRAITS FONDECYT (1150416) Proyecto 2015-2019 Coinvestigador(a)
HAVE LIPID DROPLET ABNORMALITIES AND OXIDATIVE STRESS A ROLE IN THE ADIPOSE CELL DEATH OF LIPODYSTROPHIC AGPAT2 DEFICIENT MICE? Fernández, Marta; Cortés, Víctor Proyecto (2015)
ROL DEL EPITELIO INTESTINAL EN LA DISLIPIDEMIA DIABÉTICA Fuentes, Marcela; Cortés, Víctor Proyecto (2015)
"STUDYING BROWN ADIPOGENESIS IN VIVO=> MECHANISMS FOR BROWN ADIPOSE TISSUE LACK IN AGPAT2-DEFICIENT LIPODYSTROPHIC ORGANISMS" FONDECYT (1141134) Proyecto 2014-2018 Inv. Responsable
Have lipid droplet abnormalities and oxidative stress a role in the adipose cell death of lipodystrophic Agpat2 deficient mice? FONDECYT (3150648) Proyecto 2014-2017 Inv. Patrocinante
Rol del epitelio intestinal en la dislipidemia diabetica FONDECYT (3150661) Proyecto 2014-2017 Inv. Patrocinante
STUDYING BROWN ADIPOGENESIS IN VIVO: MECHANISMS FOR BROWN ADIPOSE TISSUE LACK IN AGPAT2-DEFICIENT LIPODYSTROPHIC ORGANISMS Cortés, Víctor Proyecto (2014)
Diseño de matrices alimentarias saludables PIA (ACT1105) Proyecto 2013-2016 Investigador(a)
Efectos de la obesidad y la cirugía bariátrica sobre el sistema inflamasoma, resistencia insulínica e inflamación sistémica Pontificia Universidad Católica de Chile - Escuela de Medicina (06/13) Proyecto 2013-2014 Inv. Principal
EFFECT OF CHOLECYSTECTOMY ON SERUM TRIGLYCERIDE AND HEPATIC FAT LEVELS IN WOMEN AND THE DEVELOPMENT OF NONALCOHOLIC FATTY LIVER DISEASE IN MICE. Nervi, Flavio; Cortés, Víctor Proyecto (2013)
Effect of cholecystectomy on serum triglyceride and hepatic fat levels on women and the development of nonalcoholic fatty liver disease in mice FONDECYT (1130146) Proyecto 2013-2015 Coinvestigador(a)
Effect of gastric bypass, selective gastrectomy and duodenal-jejunal bypass on bile acid homeostasis. Role=> Associate investigator FONDECYT (1121000) Proyecto 2012-2014 Coinvestigador(a)
EFFECT OF GASTRIC BYPASS, SLEEVE GASTRECTOMY AND DUODENALJEJUNAL BYPASS ON BILE ACID HOMEOSTASIS. Escalona, Alex; Cortés, Víctor Proyecto (2012)
Evaluación de la salud oral en pacientes diabéticos tipo 2 y su relación con el control metabólico de la diabetes Pontificia Universidad Católica de Chile - Escuela de Medicina (PI03/12) Proyecto 2012-2013 Inv. Principal
PPAR-GAMMA COACTIVATOR-1 ALPHA (PGC1ALPHA) AND SEROTONIN METABOLISM: INDEPENDENT AND COMBINED EFFECTS ON MITOCHONDRIAL FUNCTION AND INSULIN SECRETION OF PANCREATIC BETA CELLS Santos, José; Cortés, Víctor Proyecto (2012)
Ppar-gamma coactivator-1 alpha and serotonin metabolism=> independent and combined effects on mitochondrial function and insulin secretion of pancreatic beta cells. FONDECYT (1120586) Proyecto 2012-2014 Coinvestigador(a)
Establecimiento y Consolidación de un Laboratorio de Investigación de la Fisiología Molecular del Tejido Adiposo, Nutrición y Metabolismo PAI (79100018) Proyecto 2011-2013 Inv. Principal
MECHANISMS OF LIPODYSTROPHY IN THE AGPAT2 DEFICIENT MOUSE Cortés, Víctor Proyecto (2011)
Mechanisms of lipodystrophy in the AGPAT2 deficient mice FONDECYT (11100168) Proyecto 2010-2012 Inv. Principal
Phenotypic characterization of AGPAT2 deficient mice, a novel model of human lipodystrophy American Heart Association (09POST2010154) Proyecto 2009-2011 Inv. Principal
ASSOCIATION BETWEEN GENE VARIANTS OF THE MITOCHONDRIAL GENOME AND PROTEOME WITH INSULIN SECRETION/SENSITIVITY INDEXES AND GLYCEMIC-RELATED TRAITS Santos, José; Cortés, Víctor Proyecto (0)


Pathophysiological connections between gallstone disease, insulin resistance, and obesity CortÃ©s V.A.; Barrera F.; Nervi F. Review ISI SCOPUS OBESITY REVIEWS (2020)
Clinical presentation and treatment of primary lipodystrophies VÍCTOR CORTÉS; JOSÉ LUIS SANTOS Review ISI SCIELO SCOPUS REVISTA MEDICA DE CHILE (2019)
Biology and pathological implications of brown adipose tissue: promises and caveats for the control of obesity and its associated complications Tapia, P; Fernandez-Galilea, M; Robledo, F; Mardones, P; Galgani, JE; Cortes, VA Review ISI SCOPUS BIOLOGICAL REVIEWS (2018)
Lipodystrophies: adipose tissue disorders with severe metabolic implications Cortes, VA; Fernandez-Galilea, M Review ISI SCOPUS Journal of Physiology and Biochemistry (2015)
Novel physiological and therapeutic implications of leptin Goldenberg D.; Santos, JL; Hodgson, MI; Cortes, VA Review ISI REVISTA MEDICA DE CHILE (2014)
ROLE OF PERIPHERAL SEROTONIN IN THE INSULIN SECRETION AND GLUCOSE HOMEOSTASIS Cataldo, LR; Cortes, VA; Galgani, JE; Olmos, PR; Santos, JL Review ISI SCOPUS NUTRICION HOSPITALARIA (2014)
Advances in the physiological and pathological implications of cholesterol Cortes, VA; Busso, D.; Mardones P.; Maiz A.; Arteaga A.; Nervi, F; Rigotti, A. Review ISI SCOPUS Biological Reviews (2013)
Rememorando la contribución de Goldstein y Brown al estudio del metabolismo del colesterol: a un cuarto de siglo del Premio Nobel de Medicina Cortés V.; Vasquez, T; Arteaga A.; Nervi, F; Rigotti, A. Review SCIELO SCOPUS REVISTA MEDICA DE CHILE (2012)
The contribution of Goldstein and Brown to the study of cholesterol metabolism Cortés V.; Vasquez, T; Arteaga A.; Nervi, F; Rigotti, A. Review ISI REVISTA MEDICA DE CHILE (2012)
New heterodimeric nuclear receptors: key metabolic regulators with relevance in the pathophysiology and therapy of dyslipidemias and diabetes mellitus Cortés V.; Quezada, N; Rigotti, A.; Maiz A. Review ISI REVISTA MEDICA DE CHILE (2005)

Victor Cortes

Associate professor

Nutrition, Diabetes and Metabolism

Pontificia Universidad Católica de Chile

Santiago, Chile

Attilio Rigotti

Full Professor

Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE - ESCUELA DE MEDICINA - DEPTO DE GASTROENTEROLOGÍA

Santiago, Chile

Attilio Rigotti

Full Professor

Nutrition, Diabetes and Metabolism

Pontificia Universidad Católica de Chile

Santiago, Chile

Silvana Zanlungo

Full Professor

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

JOSE GALGANI

ASSOCIATE PROFESSOR

NUTRITION, DIABETES AND METABOLISM; AND UDA-CIENCIAS DE LA SALUD, NUTRICION Y DIETETICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

JOSE SANTOS

Full Professor

Department of Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

PABLO TAPIA

Investigador postdoctoral

Centro de Biología Celular y Biomedicina (CEBICEM)

Universidad San Sebastián

Santiafgo, Chile

Nicolás Santander

Assistant Professor

Instituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

Dolores Busso

Associate Professor

Centro de Investigación e Innovación Biomédica

Universidad de Los Andes

Santiago, Chile

Francisco Barrera

Profesor Asociado

Gastroenterología

Pontificia Universidad Católica de Chile

Santiago, Chile

MARCO ARRESE

FULL PROFESSOR

GASTROENTEROLOGY

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Eduardo Aranda

Biochemist

Hematology

P. UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

José Suazo

Profesor Asociado

Instituto de Investigación en Ciencias Odontológicas

Universidad de Chile

Santiago, Chile

Jose Suazo

Profesor Asociado

Instituto de Investigación en Ciencias Odontológicas

Facultad de Odontologia, Universidad de Chile

Santiago, Chile

Pablo Mardones

Research Associate

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

María Mizgier

Postdoctorate

Universidad de Los Andes

Santiago, Chile

Ricardo Fernandez

Profesor Asociado A

Salud

Universidad de Los Lagos

Osorno, Chile

Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

Eugenia Morselli

Profesor Asociado de Planta Ordinaria

Fisiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago de Chile, Chile

Xavier Figueroa

Associate Professor

Departamento de Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Nicolas Quezada

Adjunct Researcher

Digestive Surgery

Pontificia Universidad Catolica de Chile

Santiago, Chile

Juan Miquel

Full Professor

Gastroenterology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

ANDRES KLEIN

Assistant Professor/Director (Head) Center for Genetics and Genomics; Director, PhD Program in Sciences and Innovation in Medicine

Centro de Genética y Genómica

Universidad del Desarrollo-Clínica Alemana

SANTIAGO, Chile

Juan Pedemonte

Profesor Asistente

Anestesiologia

Pontificia Universidad Católica de Chile

Santiago, Chile

Sergio Uribe

Associated professor

Radiology

PONTIFICIA UNIVERSIDAD CATÓLICA

Santiago, Chile

Ricardo Fernández

Associate Professor

Salud

Universidad de Los Lagos

Osorno, Chile

Enrique Brandan

Profesor Titular

Biología Celular y Molecular

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Veronica Eisner

Associate Professor

Cellular and Molecular Biology

Pontificia Universidad Católica de Chile

Santiago, Chile

Victor Antonio Cortes Mora

Líneas de Investigación

Educación

Medical Sciences, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2005

Physician surgeon, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2001

Medicine, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2000

Experiencia Académica

Postdoctoral scholar Full Time

Instructor Full Time

Assistant Professor Full Time

Associate professor Full Time

Experiencia Profesional

Attending physician - diabetology, general medicine Full Time

Attending physician Part Time

Postodoctoral fellow Full Time

Integrante grupo de estudio Fondecyt Medicina G1 Other

Formación de Capital Humano

Difusión y Transferencia

Premios y Distinciones

Honor Scholarship

Honor Scholarship

Honor Scholarship

Doctoral felloswhip

Doctoral felloswhip

President of the Republic Fellowship

Postdoctoral fellowship

Article (55)

Abstract (3)

BookSection (1)

BookWhole (2)

Proyecto (23)

Association between gene variants of the mitochondrial genome and proteome with insulin secretion/sensitivity indexes and glycemic-related traits

ASSOCIATION BETWEEN GENE VARIANTS OF THE MITOCHONDRIAL GENOME AND PROTEOME WITH INSULIN SECRETION/SENSITIVITY INDEXES AND GLYCEMIC-RELATED TRAITS

"STUDYING BROWN ADIPOGENESIS IN VIVO=> MECHANISMS FOR BROWN ADIPOSE TISSUE LACK IN AGPAT2-DEFICIENT LIPODYSTROPHIC ORGANISMS"

Have lipid droplet abnormalities and oxidative stress a role in the adipose cell death of lipodystrophic Agpat2 deficient mice?

Rol del epitelio intestinal en la dislipidemia diabetica

Diseño de matrices alimentarias saludables

Efectos de la obesidad y la cirugía bariátrica sobre el sistema inflamasoma, resistencia insulínica e inflamación sistémica

Effect of cholecystectomy on serum triglyceride and hepatic fat levels on women and the development of nonalcoholic fatty liver disease in mice

Effect of gastric bypass, selective gastrectomy and duodenal-jejunal bypass on bile acid homeostasis. Role=> Associate investigator

Evaluación de la salud oral en pacientes diabéticos tipo 2 y su relación con el control metabólico de la diabetes

Ppar-gamma coactivator-1 alpha and serotonin metabolism=> independent and combined effects on mitochondrial function and insulin secretion of pancreatic beta cells.

Establecimiento y Consolidación de un Laboratorio de Investigación de la Fisiología Molecular del Tejido Adiposo, Nutrición y Metabolismo

Mechanisms of lipodystrophy in the AGPAT2 deficient mice

Phenotypic characterization of AGPAT2 deficient mice, a novel model of human lipodystrophy

Review (10)