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Daniel Alejandro Cabrera Garcia

Investigador Adjunto

Pontificia Universidad Catolica de Chile

santiago, Chile

Hepatologia; Fisiopatologia Musculo-esqueletica; Diferenciacion celular

Magister en Ciencias Biológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2008
Doctor en Biología Celular y Molecular, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2012
Bioquímico, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007

Profesor Asistente Part Time

UNIVERSIDAD BERNARDO O'HIGGINS

Salud

Santiago, Chile

2011 - A la fecha
Docente Part Time

UNIVERSIDAD DIEGO PORTALES

Salud

Santiago, Chile

2010 - 2011
Docente a cargo del curso "La guerra de los priones". Part Time

PENTA-UC

Santiago, Chile

2011 - 2012
Docente a cargo del curso "Fuerza y movimiento: Biología celular y molecular del músculo esquelético". Part Time

PENTA-UC

Santiago, Chile

2010 - 2011
Instructor curso Biologìa Celular Part Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Ciencias Biologicas

Santiago, Chile

2008 - 2009
Ayudante del curso "Metabolismo". Part Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Ciencias Biologicas

Santiago, Chile

2004 - 2006
Ayudante del curso "Genetica Molecular Avanzada". Part Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Ciencias Biologicas

Santiago, Chile

2004 - 2006
Investigador adjunto Part Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicina

Santiago, Chile

2017 - A la fecha

Postdoctorado Full Time

Pontificia Universidad Catolica de Chile

Chile

2013 - 2015
Profesor asistente Part Time

Universidad Bernardo O´Higgins

Chile

2013 - A la fecha
Docente a cargo del curso "La guerra de los priones". Part Time

PENTA-UC

Santiago, Chile

2011 - 2012
Docente a cargo del curso "Fuerza y movimiento: Biología celular y molecular del músculo esquelético". Part Time

PENTA-UC

Santiago, Chile

2010 - 2011
Instructor del curso "Biología Celular". Part Time

Pontificia Universidad Catolica de Chile

Santiago, Chile

2008 - 2009
Ayudante del curso "Genética Molecular Avanzada". Part Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2004 - 2006
Ayudante del curso "Metabolismo". P Part Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2004 - 2006
Investigador adjunto Part Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2017 - A la fecha

Tesis postitulo en Medicina interna sub especialidad Gastroenterologia:

- Dr. Alex Ruiz (2015)
- Dr. Ricardo Cruz (2016)
- Dr. Diego San MArtin (2017)
- Dr. Rodrigo Cruz (2017)

Tesis Lic. En Biologia:

- Srta. Pamela Rojas de Santiago (2015).

Patentamiento:

Daniel Cabrera, Jaime GUTIERREZ, Gabriela Morales, Claudio CABELLO-VERRUGIO, Juan Hancke y Enrique Brandan. Pharmaco-cellular therapeutic method for the treatment of muscular dystrophies. US20140271573 A1. US 14/213,403. (http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=/netahtml/PTO/srchnum.html&r=1&f=G&l=50&s1=20140271573.PGNR.)

Difusion programa Explora-Conicyt:

2009 charla “Cuerpo y movimiento” en el Liceo Nuestra Señora de la Mercedes y Colegio Alma Mater.
2012 charla “Daño y regeneración celular” y “Uso de una droga botánica para el tratamiento de la distrofia muscular de Duchenne” en el Liceo N°1 Javiera Carrera
2019 Programa Pasantías Científicas Escolares “Protagonistas de la Ciencia 2019” con alumnos del Colegio Santa María Goretti, proyecto "Señalización paracrina en modelos in vitro de enfermedad de Hígado graso no alcohólico"

Premio Padre Hurtado

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile, 2001

Premio Excelencia Académica
Premio Mejor Tesis

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile, 2007

Premio a la mejor tesis en Ciencias Biológicas
Premio COPEC-UC

FUNDACION COPEC UNIVERSIDAD CATOLICA

Chile, 2013

Premio a la innovacion y al patentamiento
1er seleccionado Pasantìa doctoral en el extranjero

CONSEJO NACIONAL DE CIENCIA Y TECNOLOGIA

Chile, 2012

1er seleccionado Pasantìa doctoral en la UCLA de Estados Unidos
Beca Presidente de la Republica

Gobierno de Chile

Chile, 2001

Premios a la excelencia académica
Beca Juan Gómez Millas

MINEDUC

Chile, 2001

Beca excelencia Académica
Beca CONICYT

CONSEJO NACIONAL DE CIENCIA Y TECNOLOGIA

Chile, 2007

Beca CONICYT para estudios de Doctorado
Postdoctorado FONDECYT

FONDO NACIONAL DE CIENCIA,TECNOLOGIA E INNOVACION

Chile, 2013

Beca para formacion post doctoral


Chemical hypoxia induces pro-inflammatory signals in fat-laden hepatocytes and contributes to cellular crosstalk with Kupffer cells through extracellular vesicles HernÃ¡ndez A.; Geng Y.; SepÃºlveda R.; SolÃs N.; Torres J.; Arab J.P.; Barrera F.; Cabrera D.; Moshage H.; Arrese M. Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2020)
Hepatic stellate cell activation promotes alcohol-induced steatohepatitis through Igfbp3 and SerpinA12 Arab J.P.; Cabrera D.; Sehrawat T.S.; Jalan-Sakrikar N.; Verma V.K.; Simonetto D.; Cao S.; Yaqoob U.; Leon J.; Freire M.; Vargas J.I.; De Assuncao T.M.; Kwon J.H.; Guo Y.; Kostallari E.; Cai Q.; Kisseleva T.; Oh Y.; Arrese M.; Huebert R.C.; Shah V.H. Article ISI SCOPUS JOURNAL OF HEPATOLOGY (2020)
N-Acetyl Cysteine Attenuates the Sarcopenia and Muscle Apoptosis Induced by Chronic Liver Disease Abrigo, Johanna; Marin, Tabita; Aguirre, Francisco; Tacchi, Franco; Vilos, Cristian; Simon, Felipe; Arrese, Marco; Cabrera, Daniel; Cabello-Verrugio, Claudio Article ISI SCOPUS CURRENT MOLECULAR MEDICINE (2020)
Intrahepatic fatty acids composition as a biomarker of NAFLD progression from steatosis to NASH by using H-1-MRS Xavier A.; Zacconi F.; Gainza C.; Cabrera D.; Arrese M.; Uribe S.; Sing-Long C.; Andia M.E. Article ISI SCOPUS RSC ADVANCES (2019)
Mitochondrial Dysfunction in Skeletal Muscle Pathologies Abrigo, Johanna; Simon, Felipe; Cabrera, Daniel; Vilos, Cristian; Cabello-Verrugio, Claudio Article ISI SCOPUS CURRENT PROTEIN & PEPTIDE SCIENCE (2019)
Dexmedetomidine metabolic clearance is not affected by fat mass in obese patients Rolle, A; Paredes, S; Cortinez, LI; Anderson, BJ; Quezada, N; Solari, S; Allende, F; Torres, J; Cabrera, D; Contreras, V; Carmona, J; Ramirez, C; Oliveros, AM; Ibacache M. Article ISI SCOPUS BRITISH JOURNAL OF ANAESTHESIA (2018)
Long-Term, Fructose-Induced Metabolic Syndrome-Like Condition Is Associated with Higher Metabolism, Reduced Synaptic Plasticity and Cognitive Impairment in Octodon degus. Rivera, Daniela S; Lindsay, Carolina B; Codocedo, Juan F; Carreño, Laura E; Cabrera, Daniel; Arrese, Marco A; Vio, Carlos P; Bozinovic, Francisco; Inestrosa, Nibaldo C Article Molecular neurobiology (2018)
Role of Oxidative Stress as Key Regulator of Muscle Wasting during Cachexia. Ábrigo, Johanna; Elorza, Alvaro A; Riedel, Claudia A; Vilos, Cristian; Simon, Felipe; Cabrera, Daniel; Estrada, Lisbell; Cabello-Verrugio, Claudio Article Oxidative medicine and cellular longevity (2018)
Sarcopenia in a mice model of chronic liver disease=> role of the ubiquitin-proteasome system and oxidative stress. Campos, Fabián; Abrigo, Johanna; Aguirre, Francisco; Garcés, Bruno; Arrese, Marco; Karpen, Saul; Cabrera, Daniel; Andía, Marcelo E; Simon, Felipe; Cabello-Verrugio, Claudio Article Pflugers Archiv => European journal of physiology (2018)
Sarcopenia induction in a mouse model of chronic cholestatic liver disease: Role of the ubiquitin-proteasome system and oxidative stress Cabello-Verrugio, C.; Campos, F.; Abrigo, J.; Aguirre, F.; Garces, B.; Arrese, M.; Cabrera, D.; Simon, F. Article ISI JOURNAL OF HEPATOLOGY (2018)
Somatotropic Axis Dysfunction in Non-Alcoholic Fatty Liver Disease=> Beneficial Hepatic and Systemic Effects of Hormone Supplementation. Cabrera, Daniel; Cabello-Verrugio, Claudio; Solís, Nancy; San Martín, Diego; Cofré, Catalina; Pizarro, Margarita; Arab, Juan Pablo; Abrigo, Johanna; Campos, Fabián; Irigoyen, Betzabé; Carrasco-Avino, Gonzalo; Bezares, Katiuska; Riquelme, Valentina; Riquelme, Arnoldo; Arrese, Marco; Barrera, Francisco Article International journal of molecular sciences (2018)
TGF-Î² requires the activation of canonical and non-canonical signalling pathways to induce skeletal muscle atrophy. Ábrigo, Johanna; Campos, Fabian; Simon, Felipe; Riedel, Claudia; Cabrera, Daniel; Vilos, Cristian; Cabello-Verrugio, Claudio Article Biological chemistry (2018)
The pro-fibrotic connective tissue growth factor ( CTGF/CCN2) correlates with the number of necrotic-regenerative foci in dystrophic muscle Morales, MG; Acuna, MJ; Cabrera, D; Goldschmeding, R; Brandan, E Article ISI Journal of Cell Communication and Signaling (2018)
Transforming Growth Factor Beta Type I Role in Neurodegeneration=> Implications for AlzheimerÂ´s Disease. Estrada, Lisbell D; Oliveira-Cruz, Luciana; Cabrera, Daniel Article Current protein & peptide science (2018)
Triggering and resolution of inflammation in NASH. Schuster, Susanne; Cabrera, Daniel; Arrese, Marco; Feldstein, Ariel E Article Nature reviews. Gastroenterology & hepatology (2018)
Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis Cabrera D., Wree A., Povero D., Solís N., Hernandez A., Pizarro M., Moshage, H., Torres, J., Feldstein AE., Cabello-Verrugio C., Brandan E., Barrera F., Arab JP. and Arrese M. Article ISI SCOPUS SCIENTIFIC REPORTS (2017)
Bile Acids in Cholestasis and its Treatment Arab, Juan Pablo; Cabrera, Daniel; Arrese, Marco Article ISI SCOPUS Annals of Hepatology (2017)
TGF-b in HCC: When a friend Becomes an enemy? Arrese M., Hernandez A., Astete F., Cabrera D. Article Current Protein and Peptide Science (2017)
Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas Morales M.G.; Abrigo, J; Acuna M.J.; Santos R.A.; Bader M.; Brandan, E.; Simon F.; Olguin, H; cabrera, D; Cabello-Verrugio C. Article ISI SCOPUS DMM Disease Models and Mechanisms (2016)
Angiotensin-(1-7) Prevents Skeletal Muscle Atrophy Induced by Transforming Growth Factor Type Beta (TGF-beta) via Mas Receptor Activation Abrigo, J; Simon, F; Cabrera, D; Cabello-Verrugio, C Article ISI SCOPUS CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2016)
Diet-Induced Nonalcoholic Fatty Liver Disease Is Associated with Sarcopenia and Decreased Serum Insulin-Like Growth Factor-1. Cabrera, Daniel; Ruiz, Alex; Cabello-Verrugio, Claudio; Brandan, Enrique; Estrada, Lisbell; Pizarro, Margarita; Solis, Nancy; Torres, Javiera; Barrera, Francisco; Arrese, Marco Article DIGESTIVE DISEASES AND SCIENCES (2016)
High Fat Diet-Induced Skeletal Muscle Wasting Is Decreased by Mesenchymal Stem Cells Administration: Implications on Oxidative Stress, Ubiquitin Proteasome Pathway Activation, and Myonuclear Apoptosis Abrigo, J; Rivera, JC; Aravena, J; Cabrera, D; Simon, F; Ezquer, F; Ezquer, M; Cabello-Verrugio, C Article ISI SCOPUS Oxidative Medicine and Cellular Longevity (2016)
Innate Immunity and Inflammation in NAFLD/NASH Arrese, Marco; Cabrera, Daniel; Kalergis, Alexis; Feldstein, Ariel Article DIGESTIVE DISEASES AND SCIENCES (2016)
Transforming growth factor type beta (TGF-?) requires reactive oxygen species to induce skeletal muscle atrophy Abrigo, J; Rivera J.C.; Simon F.; cabrera, D; Cabello-Verrugio C. Article ISI SCOPUS Cellular Signalling (2016)
Apocynin inhibits the upregulation of TGF-beta(1) expression and ROS production induced by TGF-beta in skeletal muscle cells Abrigo, J; Morales, MG; Simon F.; cabrera, D; Di CApua G; Cabello-Verrugio, C Article ISI SCOPUS Phytomedicine (2015)
Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis Pizarro M.; Solís N.; Quintero, P.; Barrera F.; cabrera, D; Rojas-de Santiago, P; Arab, JP; Padilla, O; Roa, JC; Moshage, H; Wree, A; Inzaugarat E; Feldstein, AE; Fardella, CE; Baudrand R.; Riquelme A.; Arrese M. Article ISI SCOPUS Liver International (2015)
NFkB inhibition by Andrographolide ameliorates inflammation and fibrogenesis through inflammasome substrate depletion in experimental Non-Alcoholic Steatohepatitis (NASH) Cabrera, Daniel; Wree, Alex; Povero, Davide; Solis, Nancy; Pizarro, Margarita; Rojas de Santiago, Pamela; Torres, Javiera; Moshage, Han; Cabello-Verrugio, Claudio; Feldstein, Ariel; Brandan, Enrique Article HEPATOLOGY (2015)
Renin‐Angiotensin System: An Old Player with Novel Functions in Skeletal Muscle Claudio Cabello‐ Verrugio, María Gabriela Morales, Juan Carlos Rivera, Daniel Cabrera, Felipe Simon Article MEDICINAL RESEARCH REVIEWS (2015)
ACE2 Is Augmented in Dystrophic Skeletal Muscle and Plays a Role in Decreasing Associated Fibrosis Riquelme, Cecilia; Acua, Mara Jos; Torrejn, Javiera; Rebolledo, Daniela; Cabrera, Daniel; Santos, Robson A.; Brandan, Enrique; Sampaolesi, Maurilio Article ISI SCOPUS PLOS ONE (2014)
Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis Cabrera, Daniel; Gutiérrez, Jaime; Cabello-Verrugio, Claudio; Morales, Maria; Mezzano, Sergio; Fadic, Ricardo; Casar, Juan; Hancke, Juan L.; Brandan, Enrique Article ISI SCOPUS SKELETAL MUSCLE (2014)
Glypican-1 regulates myoblast response to HGF via Met in a lipid raft-dependent mechanism: effect on migration of skeletal muscle precursor cells Gutierrez J.; cabrera, D; Brandan, E. Article ISI SKELETAL MUSCLE (2014)
Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy Pessina P; cabrera, D; Morales, MG; Riquelme C.; Gutierrez J.; Serrano, AL.; Brandan, E.; Munoz-Canoves, P Article ISI SCOPUS SKELETAL MUSCLE (2014)
Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-beta signalling Acuña MJ; Pessina P; Olguin, H; cabrera, D; Vio, CP; Bader M.; Munoz-Canoves, P; Santos RA; Cabello-Verrugio, C; Brandan, E. Article ISI HUMAN MOLECULAR GENETICS (2014)
Inhibition of the angiotensin-converting enzyme decreases skeletal muscle fibrosis in dystrophic mice by a diminution in the expression and activity of connective tissue growth factor (CTGF/CCN-2) Morales, MG; cabrera, D; Cespedes, C; Vio, CP; Vazquez, Y; Brandan, E.; Cabello-Verrugio, C Article ISI SCOPUS Cell and Tissue Research (2013)
Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy Morales, MG; Gutierrez J.; Cabello-Verrugio, C; cabrera, D; Lipson, KE; Goldschmeding, R; Brandan, E. Article ISI SCOPUS Human Molecular Genetics (2013)
Angiotensin II receptor type 1 blockade decreases CTGF/CCN2-mediated damage and fibrosis in normal and dystrophic skeletal muscles Cabello-Verrugio, C; Morales M.G.; cabrera, D; Vio C.P.; Brandan, E. Article ISI SCOPUS Journal of Cellular and Molecular Medicine (2012)
CTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy Morales, MG; Cabello-Verrugio, C; Santander C.; cabrera, D; Goldschmeding, R; Brandan, E. Article ISI SCOPUS Journal of Pathology (2011)
Decorin Interacts with Connective Tissue Growth Factor (CTGF)/CCN2 by LRR12 Inhibiting Its Biological Activity Vial, C; Gutierrez J.; Santander C.; cabrera, D; Brandan, E. Article ISI SCOPUS Journal of Biological Chemistry (2011)
Constitutively activated dystrophic muscle fibroblasts show a paradoxical response to TGF-beta and CTGF/CCN2 Mezzano, Valeria; Cabrera, Daniel; ; Vial, Cecilia; Brandan, Enrique Article ISI Journal of Cell Communication and Signaling (2007)
Increase in decorin and biglycan in Duchenne Muscular Dystrophy: role of fibroblasts as cell source of these proteoglycans in the disease Fadic, R; Mezzano, V; Alvarez, K; cabrera, D; Holmgren, J; Brandan, E. Article ISI SCOPUS JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2006)


NFkB inhibition by Andrographolide ameliorates inflammation and fibrogenesis through inflammasome substrate depletion in experimental Non-Alcoholic Steatohepatitis (NASH) cabrera, D; Wree, A; Povero, D; Solís N.; Pizarro M.; de Santiago, PR; Torres J.; Moshage, H; Cabello-Verrugio, C; Feldstein, AE; Brandan, E.; Arrese M. Abstract ISI HEPATOLOGY (2015)
Role of Fcgamma receptors in experimental Non-Alcoholic Steatohepatitis cabrera, D; Jara, E; Cruz, R; Munoz-Durango, N; de Santiago, PR; Kalergis, A; Arrese M. Abstract ISI HEPATOLOGY (2015)
Diet-induced nonalcoholic fatty liver disease is associated with sarcopenia and decreased serum insulin growth factor-1 Ruiz A.; cabrera, D; Quintero, P.; Pizarro M.; Solís N.; Torres J.; Cabello-Verrugio, C; Brandan, E.; Barrera F.; Arrese M. Abstract ISI HEPATOLOGY (2014)
Effects of andrographolide in experimental non-alcoholic steatohepatitis cabrera, D; Pizarro M.; Solís N.; Torres J.; Brandan, E.; Arrese M. Abstract ISI HEPATOLOGY (2013)


UDCA, NorUDCA, and TUDCA in Liver Diseases: A Review of Their Mechanisms of Action and Clinical Applications Cabrera D.; Arab J.P.; Arrese M. BookWhole SCOPUS Handbook of Experimental Pharmacology (2019)


Hepatic Fatty Acid Profile in Mice with Nonalcoholic Fatty Liver Disease Using Magnetic Resonance Spectroscopy Xavier A.; Zacconi F.; Cabrera D.; Fuenzalida K.; Andia M. ConferencePaper ISI SCOPUS XIV MEDITERRANEAN CONFERENCE ON MEDICAL AND BIOLOGICAL ENGINEERING AND COMPUTING 2016 (2019)


NOVEL INSIGHTS INTO THE CROSSTALK BETWEEN MINERALOCORTICOID RECEPTOR AND EXTRACELLULAR VESICLES IN KUPFFER CELLS ACTIVATION IN NASH Jara, Evelyn; Munoz-Durango, Natalia; Solis, Nancy; Freire Cortes, Mariela; Leon, Jonathan; Arrese, Marco; Kalergis, Alexis; Cabrera, Daniel ConferencePoster (2019)
Chemical Hypoxia Determines Extracellular Vesicles Release from Fat-Laden Hepatocytes and Cellular Crosstalk with Hepatic Stellate Cells Hernandez, Alejandra; Geng, Yana; Cabrera, Daniel; Solis, Nancy; Barrera ,Francisco; Moshage, Han; Arrese, Marco ConferencePoster (2018)
Extracellular Vesicles Release from Fat-Laden Hepatocytes activates Kupffer Cells through MR activation. Cabrera, Daniel; Leon, Jonathan; Freire Cortes, Mariela; Hernandez, Alejandra; Solis, Nancy; Arab, Juan Pablo; Barrera ,Francisco; Moshage, Han; Arrese, Marco ConferencePoster (2018)
Inflammasome substrate depletion by Andrographolide improves Non-Alcoholic Steatohepatitis Cabrera, D; Rojas, P; Povero, D; Wree, A; Feldstein, A; Cabello, C; Astete L.; Manriquez, J.; Hernandez A.; Moshage, H; Brandan, E.; Arrese M. ConferencePoster (2015)
Assessment of intestinal barrier function in mice with non-alcoholic fatty liver disease subjected to intermittent hypoxia Cruz, Rodrigo; Cabrera, Daniel; Solis, Nancy; Cofré, Catalina; Hernandez, Alejandra; Barrera ,Francisco; Arrese, Marco ConferencePoster
The hypoxia-mimetic agent CoCl2 induces proinflammatory and profibrotic signals as well as inflammasome activation in liver cells Hernandez, Alejandra; Cabrera, Daniel; Barrera ,Francisco; Arrese, Marco ConferencePoster


Obeticholic acid: expanding the therapeutic landscape of NASH Arrese M.; cabrera, D; Barrera F. EditorialMaterial ISI ANNALS OF HEPATOLOGY (2015)


Bile acids and extracellular vesicles as novel biomarkers to stratify the severity of alcoholrelated liver disease: from binge drinking to alcoholic hepatitis Arab, Juan Pablo Proyecto (2020)
RANTES, a new myokine, participates in the chronic liver disease-associated sarcopenia. Cabello-Verrugio, Claudio Proyecto (2020)
Assessing the role of bile acids (BA) in NASH-related hepatocellular carcinoma Arrese, Marco Proyecto (2019)
Dissecting therapeutic role of Growth Hormone and Insulin-like Growth Factor 1 in chronic liver disease: balancing between hepatocyte protection and oncogenic potential Barrera, Francisco Proyecto (2019)
Role of Angiotensin 1-7 on skeletal muscle wasting Association-Francaise Contre Les Myopathies (AFM) (AFM 16670) Proyecto 2017-2032 Investigador(a)
Searching for the missing link between hepatocyte injury and liver inflammation: The role of mineralocorticoid receptor in Kupffer cells activation Cabrera, Daniel Proyecto (2017)
SEARCHING FOR THE MISSING LINK BETWEEN HEPATOCYTE INJURY AND LIVER INFLAMMATION=> THE ROLE OF MINERALOCORTICOID RECEPTOR IN KUPFFER CELLS ACTIVATION FONDECYT (11171001) Proyecto 2017-2019 Inv. Responsable
MECHANISMS INVOLVED IN THE CACHEXIA INDUCED BY CHRONIC LIVER DISEASES FONDECYT (1161646) Proyecto 2016-2020 Coinvestigador(a)
MECHANISMS INVOLVED IN THE CACHEXIA INDUCED BY CHRONIC LIVER DISEASES FONDECYT (1161646) Proyecto 2016-2020 Coinvestigador(a)
Evaluating somatotropic axis dysregulation and protective role of growth hormone and insulin like growth factor 1 supplementation in non-alcoholic fatty liver disease FONDECYT (1150311) Proyecto 2015-2019 Coinvestigador(a)
LIVER INJURY IN NON-ALCOHOLIC FATTY LIVER DISEASE=> EXPLORING NEW MODULATORS AND BIOMARKERS FONDECYT (1150327) Proyecto 2015-2019 Personal técnico y/o de apoyo
LIVER INJURY IN NON-ALCOHOLIC FATTY LIVER DISEASE=> EXPLORING NEW MODULATORS AND BIOMARKERS FONDECYT (1150327) Proyecto 2015-2019 Personal técnico y/o de apoyo
THE EFFECT OF OBESITY IN DEXMEDETOMIDINE METABOLIC CLEARANCE FONDECYT (1150197) Proyecto 2015-2018 Personal técnico y/o de apoyo
THE EFFECT OF OBESITY IN DEXMEDETOMIDINE METABOLIC CLEARANCE FONDECYT (1150197) Proyecto 2015-2018 Personal técnico y/o de apoyo
Centro de envejecimiento y regeneración Inestrosa, Nibaldo Proyecto (2014)
Angiotensina 1-7 modula la señalizacion dependiente del factor de crecimiento tipo insulinico 1 y el factor nuclear kappa b en un modelo de atrofia muscular esqueletica inducido por lipopolisacarido Morales, Maria Proyecto (2013)
Centro de Envejecimiento y Regeneración (CARE) FONDAP (CARE Chile) Proyecto 2013-2017 Postdoctorado
HEPATITIS C VIRUS EXPLOITS THE HEPATIC LIPID PATHWAYS=> ROLE OF NPC1L1 IN HCV INFECTION. FONDECYT (1130357) Proyecto 2013-2017 Personal técnico y/o de apoyo
HEPATITIS C VIRUS EXPLOITS THE HEPATIC LIPID PATHWAYS=> ROLE OF NPC1L1 IN HCV INFECTION. FONDECYT (1130357) Proyecto 2013-2017 Personal técnico y/o de apoyo
Hitting the brakes in the innate immune response=> synergic action of TGR5 and andrographolide in non-alcoholic steatohepatitis FONDECYT (3140396) Proyecto 2013-2016 Inv. Responsable
Anti-atrophic role of angiotensin 1-7 on skeletal muscle Cabello-Verrugio, Claudio Proyecto (2012)
DROGA BOTÁNICA PARA EL PARA EL TRATAMIENTO DE LA FIBROSIS CARDÍACA FONDEF (VIU 110070) Proyecto 2012-2012 Director(a)
EXPLORING NEW PATHOPHYSIOLOGICAL PATHWAYS IN NONALCOHOLIC FATTY LIVER DISEASE FONDECYT (FONDECYT R) Proyecto 2011-2014 Investigador(a)
Novel antifibrotic role of the ace2/angiotensin 1-7/mas axis in skeletal muscular dystrophies Brandan, Enrique Proyecto (2011)
Reduced reck levels improve the muscle cell therapy and diminish the fibrosis associated to the dystrophic muscle Gutierrez-Perez J. Proyecto (2011)
Centro de Envejecimiento y Regeneración (CARE) FONDAP (CARE Chile) Proyecto 2008-2012 Investigador(a)
CTGF the factor involved in fibrosis development in DMD Muscular Dystrophy Association (MDA). Estados Unidos. (MDA 2004/2007) Proyecto 2008-2011 Investigador(a)
ENFERMEDAD RENAL CRONICA E HIPERTENSION ARTERIAL: PARTICIPACION DE CICLOOXIGENASA-2 Y ANGIOTENSINA 1-7 Vio, Carlos Proyecto (2008)
Profibrotic effect of the renin-angiotensin system and connective tissue growth factor (ctgf) in dystrophic skeletal muscle Cabello-Verrugio, Claudio Proyecto (2008)
DROGA BOTANICA (BOTANICAL DRUG PARA LA FDA DE EEUU) PARA EL TRATAMIENTO EN ENFERMEDADES CRONICAS ASO CIADAS A FIBROSIS DE ALTA INCIDENCIA NACIONAL Y MUNDIAL FONDEF (FONDEF D07) Proyecto 2007-2010 Investigador(a)
Skeletal muscle formation, function and disease. FONDAP (FONDAP) Proyecto 2005-2009 Investigador(a)
DMD fibrosis=> Role of CTGF, LRP and proteoglycans Muscular Dystrophy Association (MDA) Estados Unidos. (MDA 2004/2007) Proyecto 2004-2007 Tesista
Expresion de moleculas de superficie celular en distrofinopatia: mdx versus duchenne Fadic R, Ricardo Proyecto (2002)
Function of proteoglycans during skeletal muscle differentiation Howard Hughes Medical Institute (HHMI). Estados Unidos). Investigador Internacional. (HHMI 2002/2006) Proyecto 2002-2006 Tesista


Central role of transforming growth factor type beta 1 in skeletal muscle dysfunctions: An update on therapeutic strategies Abrigo J.; Simon F.; Cabrera D.; CÃ³rdova G.; Trollet C.; Cabello-Verrugio C. Review ISI SCOPUS (2018)
Innate Immunity and Inflammation in NAFLD/NASH Arrese M.; cabrera, D; Kalergis, A.M.; Feldstein A.E. Review ISI SCOPUS (2016)
Renin-Angiotensin System: An Old Player with Novel Functions in Skeletal Muscle Cabello-Verrugio, C; Morales, MG; Rivera, JC; cabrera, D; Simon F. Review ISI SCOPUS Medicinal Research Reviews (2015)

Daniel Cabrera

Investigador Adjunto

Gastroenterología

Pontificia Universidad Catolica de Chile

santiago, Chile

Enrique Brandan

Profesor Titular

Biología Celular y Molecular

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Claudio Cabello

Full Professor

Ciencias Biologicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

MARCO ARRESE

FULL PROFESSOR

GASTROENTEROLOGY

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Felipe Simon

Profesor Titular

Department of Biological Sciences

UNIVERSIDAD ANDRES BELLO FAC DE CS BIOLOGICAS, DPTO DE CS BIOLOGICAS

Santiago, Chile

Johanna Ábrigo

Bioquímico

Centro de Bioinformática y Biología Integrativa

Santiago, Chile

Jaime Gutierrez

Associate Professor and Researcher

Tecnología Médica

Universidad San Sebastián

Santiago, Chile

Juan Arab

Assistant Professor

Gastroenterologia

Pontificia Universidad Católica de Chile

Santiago, Chile

Francisco Barrera

Profesor Asociado

Gastroenterología

Pontificia Universidad Católica de Chile

Santiago, Chile

Margarita Pizarro

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

María Acuña

Directora de Investigación, académico e investigador

Universidad Bernardo O´Higgins

Santiago, Chile

Carlos Vio

Profesor

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Aline Carvalho da Silva

Assistant Professor

Universidad de Santiago de Chile

Región metropolitana, Chile

Flavia Zacconi

Associate Professor

Organic Chemistry

Pontificia Universidad Católica de Chile

Santiago, Chile

Cristian Vilos

Académico Jornada Completa

Medicina

Universidad de Talca

Talca, Chile

Maria Vial

Associate Professor/Profesor Asociado

Instituto de Ciencias e Innovación de Medicina

UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

Hugo Olguin

Profesor Asociado

Biología Celular y Molecular

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Alexis Kalergis

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

Juan Rivera

Investigador

Instituto Milenio de Inmunología e Inmunoterapia

Santiago, Chile

Hugo Olguin

Profesor Asociado

Biología Celular y Molecular

Pontificia Universidad Católica de Chile

Santiago, Chile

ricardo fadic

Jefe de Division

Division de Neurociencias

DEPARTAMENTO DE NEUROLOGÍA, FACULTAD DE MEDICINA, P. UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Carlos Cespedes

Tecnologo Medico

Fisiologia

P. Universidad Católica de Chile

Santiago, Chile

Sandra Solari

Profesor Clinico Asociado

Laboratorios Clinicos

Facultad de Medicina - PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Fernando Ezquer

Full Professor

Center for Regenerative Medicine

Universidad del Desarrollo

Santiago, Chile

Fidel Allende

Quimico

Laboratorios Clinicos

Pontificia Universidad Católica de Chile

Santiago, Chile

Arnoldo Riquelme

Director UDA Ciencias de la Salud (Carreras de Nutrición y dietética, Fonoaudiología y Kinesiología)

Gastroenterología

Pontificia Universidad Católica de Chile

Santiago, Chile

Victor Contreras

Director y Gestor de Proyectos

Anestesiologia

Pontificia Universidad Catolica de Chile

Santiago, Chile

Mauricio Ibacache

Profesor Asociado

Pontificia Universidad Católica de Chile

santiago centro, Chile

Evelyn Jara

Docente/Investigador

Ciencias Básicas

Universidad Santo Tomás

Temuco, Chile

Daniela Rebolledo

Académico

Centro de Excelencia en Biomedicina de Magallanes

Punta Arenas, Chile

Arnoldo Riquelme

Profesor titular

Gastroenterología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE GASTROENTEROLOGÍA

Santiago, Chile

Rene Baudrand

Profesor Asociado

Endocrinología

Pontificia Universidad Católica de Chile

Santiago, Chile

Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

Oslando Padilla

Estadístico

Salud Pública

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Yaneisi Vazquez

Directora técnica de proyectos

Genética Molecular

Pontificia Universidad Católica de Chile

Santiago, Chile

Marcelo Andia

Associate Professor

Radiology

Pontificia Universidad Catolica de Chile

Santiago, Chile

Sergio Mezzano

Catedratico

Medicina

Universidad Austral de Chile

Valdivia, Chile

Alejandra Hernández

Investigadora postdoctoral

Depto. Bioquímica y Biología Molecular

ACCDiS-Universidad de Chile

Santiago, Chile

Luis Cortínez

DIVISIÓN DE ANESTESIOLOGÍA, ESCUELA DE MEDICINA, PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Carlos Sing-Long

Assistant Professor

Instituto de Ingeniería Matemática y Computacional

Pontificia Universidad Católica de Chile

Santiago, Chile

Sergio Uribe

Associated professor

Radiology

PONTIFICIA UNIVERSIDAD CATÓLICA

Santiago, Chile

Jose Ignacio Vargas

Assistant Professor

GASTROENTEROLOGY

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

Rolando Sepúlveda

Director Departamento Medicina Interna

Medicina Interna

Universidad de La Frontera

Temuco, Chile

Daniel Alejandro Cabrera Garcia

Líneas de Investigación

Educación

Magister en Ciencias Biológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2008

Doctor en Biología Celular y Molecular, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2012

Bioquímico, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007

Experiencia Académica

Profesor Asistente Part Time

Docente Part Time

Docente a cargo del curso "La guerra de los priones". Part Time

Docente a cargo del curso "Fuerza y movimiento: Biología celular y molecular del músculo esquelético". Part Time

Instructor curso Biologìa Celular Part Time

Ayudante del curso "Metabolismo". Part Time

Ayudante del curso "Genetica Molecular Avanzada". Part Time

Investigador adjunto Part Time

Experiencia Profesional

Postdoctorado Full Time

Profesor asistente Part Time

Docente a cargo del curso "La guerra de los priones". Part Time

Docente a cargo del curso "Fuerza y movimiento: Biología celular y molecular del músculo esquelético". Part Time

Instructor del curso "Biología Celular". Part Time

Ayudante del curso "Genética Molecular Avanzada". Part Time

Ayudante del curso "Metabolismo". P Part Time

Investigador adjunto Part Time

Formación de Capital Humano

Difusión y Transferencia

Premios y Distinciones

Premio Padre Hurtado

Premio Mejor Tesis

Premio COPEC-UC

1er seleccionado Pasantìa doctoral en el extranjero

Beca Presidente de la Republica

Beca Juan Gómez Millas

Beca CONICYT

Postdoctorado FONDECYT

Article (40)

Abstract (4)

BookWhole (1)

ConferencePaper (1)

ConferencePoster (6)

EditorialMaterial (1)

Proyecto (34)

Role of Angiotensin 1-7 on skeletal muscle wasting

SEARCHING FOR THE MISSING LINK BETWEEN HEPATOCYTE INJURY AND LIVER INFLAMMATION=> THE ROLE OF MINERALOCORTICOID RECEPTOR IN KUPFFER CELLS ACTIVATION

MECHANISMS INVOLVED IN THE CACHEXIA INDUCED BY CHRONIC LIVER DISEASES

MECHANISMS INVOLVED IN THE CACHEXIA INDUCED BY CHRONIC LIVER DISEASES

Evaluating somatotropic axis dysregulation and protective role of growth hormone and insulin like growth factor 1 supplementation in non-alcoholic fatty liver disease

LIVER INJURY IN NON-ALCOHOLIC FATTY LIVER DISEASE=> EXPLORING NEW MODULATORS AND BIOMARKERS

LIVER INJURY IN NON-ALCOHOLIC FATTY LIVER DISEASE=> EXPLORING NEW MODULATORS AND BIOMARKERS

THE EFFECT OF OBESITY IN DEXMEDETOMIDINE METABOLIC CLEARANCE

THE EFFECT OF OBESITY IN DEXMEDETOMIDINE METABOLIC CLEARANCE

Centro de Envejecimiento y Regeneración (CARE)

HEPATITIS C VIRUS EXPLOITS THE HEPATIC LIPID PATHWAYS=> ROLE OF NPC1L1 IN HCV INFECTION.

HEPATITIS C VIRUS EXPLOITS THE HEPATIC LIPID PATHWAYS=> ROLE OF NPC1L1 IN HCV INFECTION.

Hitting the brakes in the innate immune response=> synergic action of TGR5 and andrographolide in non-alcoholic steatohepatitis

DROGA BOTÁNICA PARA EL PARA EL TRATAMIENTO DE LA FIBROSIS CARDÍACA

EXPLORING NEW PATHOPHYSIOLOGICAL PATHWAYS IN NONALCOHOLIC FATTY LIVER DISEASE

Centro de Envejecimiento y Regeneración (CARE)

CTGF the factor involved in fibrosis development in DMD

DROGA BOTANICA (BOTANICAL DRUG PARA LA FDA DE EEUU) PARA EL TRATAMIENTO EN ENFERMEDADES CRONICAS ASO CIADAS A FIBROSIS DE ALTA INCIDENCIA NACIONAL Y MUNDIAL

Skeletal muscle formation, function and disease.

DMD fibrosis=> Role of CTGF, LRP and proteoglycans

Function of proteoglycans during skeletal muscle differentiation

Review (3)