Estudio de enfermedad celíaca en pacientes con psoriasis

Calderón H, Perla; Valdés A, Pilar; Zemelman D, Viviana; Poniachik T, Jaime; Hurtado H, Carmen; Garmendia M, María Luisa; Abumohor G, Patricia; Echavarri P, María Cristina

Abstract

Background: A possible relationship has been reported between psoriasis and celiac disease, with common pathogenic mechanisms that may need further investigation. Aim: To investigate the presence of clinical and serological markers for celiac disease in a group of Chilean psoriatic patients. Material and methods: We included 80 psoriatic patients (42 males) aged 16 to 79 years, whose serum was tested for antitransglutaminase antibodies (ATGA) and antiendomysial antibodies (AEMA). Patients with weakly positive AEMA tests were also tested for antigliadin antibodies (AGA). Results: In six patients (7.5%), AEMA and AGA were positive and one patient was positive for ATGA. An upper gastrointestinal endoscopy and duodenal biopsy was offered to these six patients and five accepted the procedure. Only one had a pathological diagnosis of celiac disease. Conclusions: Only one of 80 patients with psoriasis had celiac disease (1.2%). Other four patients with positive serologic markers had a normal duodenal biopsy. This group of patients may have latent celiac disease and they should be followed up

Más información

Título según SCIELO: Estudio de enfermedad celíaca en pacientes con psoriasis
Título de la Revista: REVISTA MEDICA DE CHILE
Volumen: 135
Número: 10
Editorial: SOC MEDICA SANTIAGO
Fecha de publicación: 2007
Página de inicio: 1296
Página final: 1303
Idioma: es
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001000010&lng=en&nrm=iso&tlng=en
DOI:

10.4067/S0034-98872007001000010

Notas: SCIELO